Search Results - (Author, Cooperation:C. Pons)
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1Ibarra-Castillo, C., Guisado-Clavero, M., Violan-Fors, C., Pons-Vigues, M., Lopez-Jimenez, T., Roso-Llorach, A., Collaborators, Pujol-ribera, Duarte-salles, Murray
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-02-13Publisher: BMJ Publishing GroupPrint ISSN: 0143-005XElectronic ISSN: 1470-2738Topics: MedicinePublished by: -
2A. L. Powell ; C. V. Nguyen ; T. Hill ; K. L. Cheng ; R. Figueroa-Balderas ; H. Aktas ; H. Ashrafi ; C. Pons ; R. Fernandez-Munoz ; A. Vicente ; J. Lopez-Baltazar ; C. S. Barry ; Y. Liu ; R. Chetelat ; A. Granell ; A. Van Deynze ; J. J. Giovannoni ; A. B. Bennett
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-06-30Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Chloroplasts/*genetics/physiology ; Chromosome Mapping ; Chromosomes, Plant ; Fruit/genetics/growth & development ; Lycopersicon esculentum/*genetics/*growth & development ; Phenotype ; Plant Proteins/*genetics/physiology ; Transcription Factors/*genetics/physiologyPublished by: -
3Kuzmin, E., Vander; Sluis, B., Wang, W., Tan, G., Deshpande, R., Chen, Y., Usaj, M., Balint, A., Mattiazzi Usaj, M., van Leeuwen, J., Koch, E. N., Pons, C., Dagilis, A. J., Pryszlak, M., Wang, J. Z. Y., Hanchard, J., Riggi, M., Xu, K., Heydari, H., San Luis, B.-J., Shuteriqi, E., Zhu, H., Van Dyk, N., Sharifpoor, S., Costanzo, M., Loewith, R., Caudy, A., Bolnick, D., Brown, G. W., Andrews, B. J., Boone, C., Myers, C. L.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Genetics, Online OnlyPublished by: -
4Staff View
ISSN: 0014-195XTopics: English, American StudiesURL: -
5Staff View
ISSN: 0029-554XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
6Kiffel, L. ; Pons, C. ; Sonnier, M. ; Lemoine, A. ; Hoellinger, H. ; Leroux, J.-P.
Amsterdam : ElsevierStaff ViewISSN: 0309-1651Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0014-195XTopics: English, American StudiesNotes: ÉTUDES CRITIQUESURL: -
8Long-term effects of a tryptophan-free diet on serotonin metabolism and sleep-waking balance in ratsStaff View
ISSN: 1432-1106Keywords: Rat ; Tryptophan deprivation ; Sleep circadian rhythm ; Serotonin metabolismSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary 1. A long-term (up to 16 weeks) tryp-tophan (TRP)-free diet was administered to chronically implanted adult rats in order to study the effects of a sustained reduction of endogenous brain serotonin (5-HT) levels on the sleep-waking cycle. Twentyfour hours polygraphic recordings were made either periodically on an EEG apparatus, or uninterruptedly over 50 days by a frequency analyser. Quantitative changes in wakefulness (W), slow wave sleep (SWS) and paradoxical sleep (PS), as well as the number and duration of these episodes, were studied over 24 h, with a dark period (DP) and a light period (LP). Biochemical changes in 5-HT metabolism were measured in both plasma and brain. 2. Under control conditions, the percentage of W was twice as great in DP as in LP, while the quantities of SWS and PS were twice as high in LP as in DP. Surprisingly, in spite of a decrease of about 50% in brain 5-HT under TRP-deprived conditions, no dramatic changes were observed in the qualitative or quantitative aspects of W, SWS or PS. The only electrocorticographic (ECoG) change was a disappearance of sleep spindles, which became total after 14 weeks. During the first month, there was a 7% increase in W accompanied by a 6% decrease in SWS and a 5–9% reduction in PS. Later, W and SWS returned to their control values, while the PS deficit persisted throughout the TRP-deprivation period. Despite the absence of severe quantitative disturbances over 24 h, an internal reorganization of the sleep cycle took place. This new balance, established after 2 months, was characterized by a tendency toward an equal distribution of the stages in DP and LP, resulting in the disappearance of the sleep circadian rhythm. 3. Our results are compared with those of other authors who lowered the endogenous 5-HT levels by various means, including ‘acute’ or partial TRP-deprivation. The present findings suggest that adaptive cerebral mechanisms are able to compensate for the disturbances in 5-HT metabolism, in structures responsible for W and SWS. They indicate that the neurohumoral processes underlying sleep circadian rhythm in the rat are serotoninergic and/or noradrenergic.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1432-1106Keywords: Cerebellar nuclei ; Motor synergies ; Simple movements ; Movement topographySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Movements elicited by the stimulation of the cerebellar nuclei were studied in alert baboons chronically prepared. The motor responses were filmed and recorded in eight muscles through chronically implanted electrodes. Two types of motor effects were observed: (1) Simple movements that concerned the unidirectional displacement of a limb segment. (2) Complex movements that involved distinct and frequently noncontiguous muscles were stereotyped and could not be dissociated. These movements are defined as motor synergies. Electromyographic study allowed us to investigate the motor response latencies and the modality of cerebellar control on musculature. Simple movements were due to the activation of muscles within the involved segment in addition to the co-contraction of muscles of a nearby segment. Thus they could be due to a cerebellar control over muscular synergies. Complex movements would correspond to the simultaneous activation of distinct muscular groups and could also be the outcome of a cerebellar control on motor synergies. Thus the effects of the interposed nucleus concern preferably flexor muscles whereas the effects of the dentate nucleus appear to be equally distributed among flexor and extensor muscles. Somatotopic motor localization were evidenced both in the interposed and dentate nuclei: there are somatotopic relations between every region of the interposed nucleus and musculature. As regards the dentate nucleus, two subdivisions were distinguished according to the complexity of elicited motor effects: (A) an antero-medial region from which motor synergies can be elicited. (B) a postero-lateral region giving rise to simple movements, mainly hand movements.Type of Medium: Electronic ResourceURL: