Search Results - (Author, Cooperation:C. Nourse)

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  1. 1
    A. M. Patch ; E. L. Christie ; D. Etemadmoghadam ; D. W. Garsed ; J. George ; S. Fereday ; K. Nones ; P. Cowin ; K. Alsop ; P. J. Bailey ; K. S. Kassahn ; F. Newell ; M. C. Quinn ; S. Kazakoff ; K. Quek ; C. Wilhelm-Benartzi ; E. Curry ; H. S. Leong ; A. Hamilton ; L. Mileshkin ; G. Au-Yeung ; C. Kennedy ; J. Hung ; Y. E. Chiew ; P. Harnett ; M. Friedlander ; M. Quinn ; J. Pyman ; S. Cordner ; P. O'Brien ; J. Leditschke ; G. Young ; K. Strachan ; P. Waring ; W. Azar ; C. Mitchell ; N. Traficante ; J. Hendley ; H. Thorne ; M. Shackleton ; D. K. Miller ; G. M. Arnau ; R. W. Tothill ; T. P. Holloway ; T. Semple ; I. Harliwong ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Idrisoglu ; T. J. Bruxner ; A. N. Christ ; B. Poudel ; O. Holmes ; M. Anderson ; C. Leonard ; A. Lonie ; N. Hall ; S. Wood ; D. F. Taylor ; Q. Xu ; J. L. Fink ; N. Waddell ; R. Drapkin ; E. Stronach ; H. Gabra ; R. Brown ; A. Jewell ; S. H. Nagaraj ; E. Markham ; P. J. Wilson ; J. Ellul ; O. McNally ; M. A. Doyle ; R. Vedururu ; C. Stewart ; E. Lengyel ; J. V. Pearson ; A. deFazio ; S. M. Grimmond ; D. D. Bowtell
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-10-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    N. Waddell ; M. Pajic ; A. M. Patch ; D. K. Chang ; K. S. Kassahn ; P. Bailey ; A. L. Johns ; D. Miller ; K. Nones ; K. Quek ; M. C. Quinn ; A. J. Robertson ; M. Z. Fadlullah ; T. J. Bruxner ; A. N. Christ ; I. Harliwong ; S. Idrisoglu ; S. Manning ; C. Nourse ; E. Nourbakhsh ; S. Wani ; P. J. Wilson ; E. Markham ; N. Cloonan ; M. J. Anderson ; J. L. Fink ; O. Holmes ; S. H. Kazakoff ; C. Leonard ; F. Newell ; B. Poudel ; S. Song ; D. Taylor ; S. Wood ; Q. Xu ; J. Wu ; M. Pinese ; M. J. Cowley ; H. C. Lee ; M. D. Jones ; A. M. Nagrial ; J. Humphris ; L. A. Chantrill ; V. Chin ; A. M. Steinmann ; A. Mawson ; E. S. Humphrey ; E. K. Colvin ; A. Chou ; C. J. Scarlett ; A. V. Pinho ; M. Giry-Laterriere ; I. Rooman ; J. S. Samra ; J. G. Kench ; J. A. Pettitt ; N. D. Merrett ; C. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; N. B. Jamieson ; J. S. Graham ; S. P. Niclou ; R. Bjerkvig ; R. Grutzmann ; D. Aust ; R. H. Hruban ; A. Maitra ; C. A. Iacobuzio-Donahue ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; V. Corbo ; C. Bassi ; M. Falconi ; G. Zamboni ; G. Tortora ; M. A. Tempero ; A. J. Gill ; J. R. Eshleman ; C. Pilarsky ; A. Scarpa ; E. A. Musgrove ; J. V. Pearson ; A. V. Biankin ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-02-27
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenocarcinoma/drug therapy/genetics ; Animals ; Carcinoma, Pancreatic Ductal/drug therapy/genetics ; *DNA Mutational Analysis ; DNA Repair/genetics ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genetic Markers/genetics ; Genome, Human/*genetics ; Genomic Instability/genetics ; *Genomics ; Genotype ; Humans ; Mice ; Mutation/*genetics ; Pancreatic Neoplasms/classification/drug therapy/*genetics ; Platinum/pharmacology ; Point Mutation/genetics ; Poly(ADP-ribose) Polymerase Inhibitors ; Xenograft Model Antitumor Assays
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    P. Bailey ; D. K. Chang ; K. Nones ; A. L. Johns ; A. M. Patch ; M. C. Gingras ; D. K. Miller ; A. N. Christ ; T. J. Bruxner ; M. C. Quinn ; C. Nourse ; L. C. Murtaugh ; I. Harliwong ; S. Idrisoglu ; S. Manning ; E. Nourbakhsh ; S. Wani ; L. Fink ; O. Holmes ; V. Chin ; M. J. Anderson ; S. Kazakoff ; C. Leonard ; F. Newell ; N. Waddell ; S. Wood ; Q. Xu ; P. J. Wilson ; N. Cloonan ; K. S. Kassahn ; D. Taylor ; K. Quek ; A. Robertson ; L. Pantano ; L. Mincarelli ; L. N. Sanchez ; L. Evers ; J. Wu ; M. Pinese ; M. J. Cowley ; M. D. Jones ; E. K. Colvin ; A. M. Nagrial ; E. S. Humphrey ; L. A. Chantrill ; A. Mawson ; J. Humphris ; A. Chou ; M. Pajic ; C. J. Scarlett ; A. V. Pinho ; M. Giry-Laterriere ; I. Rooman ; J. S. Samra ; J. G. Kench ; J. A. Lovell ; N. D. Merrett ; C. W. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; K. Moran-Jones ; N. B. Jamieson ; J. S. Graham ; F. Duthie ; K. Oien ; J. Hair ; R. Grutzmann ; A. Maitra ; C. A. Iacobuzio-Donahue ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; V. Corbo ; C. Bassi ; B. Rusev ; P. Capelli ; R. Salvia ; G. Tortora ; D. Mukhopadhyay ; G. M. Petersen ; D. M. Munzy ; W. E. Fisher ; S. A. Karim ; J. R. Eshleman ; R. H. Hruban ; C. Pilarsky ; J. P. Morton ; O. J. Sansom ; A. Scarpa ; E. A. Musgrove ; U. M. Bailey ; O. Hofmann ; R. L. Sutherland ; D. A. Wheeler ; A. J. Gill ; R. A. Gibbs ; J. V. Pearson ; A. V. Biankin ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2016
    Staff View
    Publication Date:
    2016-02-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Carcinoma, Pancreatic ; Ductal/classification/genetics/immunology/metabolism/pathology ; Cell Line, Tumor ; DNA Methylation ; DNA-Binding Proteins/genetics ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Genes, Neoplasm/*genetics ; Genome, Human/*genetics ; *Genomics ; Hepatocyte Nuclear Factor 3-beta/genetics ; Hepatocyte Nuclear Factor 3-gamma/genetics ; Histone Demethylases/genetics ; Homeodomain Proteins/genetics ; Humans ; Mice ; Mutation/*genetics ; Nuclear Proteins/genetics ; Pancreatic Neoplasms/*classification/*genetics/immunology/metabolism/pathology ; Prognosis ; Receptors, Cytoplasmic and Nuclear/genetics ; Survival Analysis ; Trans-Activators/genetics ; Transcription Factors/genetics ; Transcription, Genetic ; Transcriptome ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Proteins/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    A. V. Biankin ; N. Waddell ; K. S. Kassahn ; M. C. Gingras ; L. B. Muthuswamy ; A. L. Johns ; D. K. Miller ; P. J. Wilson ; A. M. Patch ; J. Wu ; D. K. Chang ; M. J. Cowley ; B. B. Gardiner ; S. Song ; I. Harliwong ; S. Idrisoglu ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Wani ; M. Gongora ; M. Pajic ; C. J. Scarlett ; A. J. Gill ; A. V. Pinho ; I. Rooman ; M. Anderson ; O. Holmes ; C. Leonard ; D. Taylor ; S. Wood ; Q. Xu ; K. Nones ; J. L. Fink ; A. Christ ; T. Bruxner ; N. Cloonan ; G. Kolle ; F. Newell ; M. Pinese ; R. S. Mead ; J. L. Humphris ; W. Kaplan ; M. D. Jones ; E. K. Colvin ; A. M. Nagrial ; E. S. Humphrey ; A. Chou ; V. T. Chin ; L. A. Chantrill ; A. Mawson ; J. S. Samra ; J. G. Kench ; J. A. Lovell ; R. J. Daly ; N. D. Merrett ; C. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; N. Kakkar ; F. Zhao ; Y. Q. Wu ; M. Wang ; D. M. Muzny ; W. E. Fisher ; F. C. Brunicardi ; S. E. Hodges ; J. G. Reid ; J. Drummond ; K. Chang ; Y. Han ; L. R. Lewis ; H. Dinh ; C. J. Buhay ; T. Beck ; L. Timms ; M. Sam ; K. Begley ; A. Brown ; D. Pai ; A. Panchal ; N. Buchner ; R. De Borja ; R. E. Denroche ; C. K. Yung ; S. Serra ; N. Onetto ; D. Mukhopadhyay ; M. S. Tsao ; P. A. Shaw ; G. M. Petersen ; S. Gallinger ; R. H. Hruban ; A. Maitra ; C. A. Iacobuzio-Donahue ; R. D. Schulick ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; P. Capelli ; V. Corbo ; M. Scardoni ; G. Tortora ; M. A. Tempero ; K. M. Mann ; N. A. Jenkins ; P. A. Perez-Mancera ; D. J. Adams ; D. A. Largaespada ; L. F. Wessels ; A. G. Rust ; L. D. Stein ; D. A. Tuveson ; N. G. Copeland ; E. A. Musgrove ; A. Scarpa ; J. R. Eshleman ; T. J. Hudson ; R. L. Sutherland ; D. A. Wheeler ; J. V. Pearson ; J. D. McPherson ; R. A. Gibbs ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-10-30
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Axons/*metabolism ; Carcinoma, Pancreatic Ductal/*genetics/*pathology ; Gene Dosage ; Gene Expression Regulation, Neoplastic ; Genome/*genetics ; Humans ; Kaplan-Meier Estimate ; Mice ; Mutation ; Pancreatic Neoplasms/*genetics/*pathology ; Proteins/genetics ; Signal Transduction
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    A. M. Patch ; E. L. Christie ; D. Etemadmoghadam ; D. W. Garsed ; J. George ; S. Fereday ; K. Nones ; P. Cowin ; K. Alsop ; P. J. Bailey ; K. S. Kassahn ; F. Newell ; M. C. Quinn ; S. Kazakoff ; K. Quek ; C. Wilhelm-Benartzi ; E. Curry ; H. S. Leong ; A. Hamilton ; L. Mileshkin ; G. Au-Yeung ; C. Kennedy ; J. Hung ; Y. E. Chiew ; P. Harnett ; M. Friedlander ; M. Quinn ; J. Pyman ; S. Cordner ; P. O'Brien ; J. Leditschke ; G. Young ; K. Strachan ; P. Waring ; W. Azar ; C. Mitchell ; N. Traficante ; J. Hendley ; H. Thorne ; M. Shackleton ; D. K. Miller ; G. M. Arnau ; R. W. Tothill ; T. P. Holloway ; T. Semple ; I. Harliwong ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Idrisoglu ; T. J. Bruxner ; A. N. Christ ; B. Poudel ; O. Holmes ; M. Anderson ; C. Leonard ; A. Lonie ; N. Hall ; S. Wood ; D. F. Taylor ; Q. Xu ; J. L. Fink ; N. Waddell ; R. Drapkin ; E. Stronach ; H. Gabra ; R. Brown ; A. Jewell ; S. H. Nagaraj ; E. Markham ; P. J. Wilson ; J. Ellul ; O. McNally ; M. A. Doyle ; R. Vedururu ; C. Stewart ; E. Lengyel ; J. V. Pearson ; A. deFazio ; S. M. Grimmond ; D. D. Bowtell
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-05-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Cohort Studies ; Cyclin E/genetics ; Cystadenocarcinoma, Serous/drug therapy/genetics ; DNA Methylation ; DNA Mutational Analysis ; DNA-Binding Proteins/genetics ; Drug Resistance, Neoplasm/*drug effects/*genetics ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genes, Neurofibromatosis 1 ; Genome, Human/*genetics ; Germ-Line Mutation/genetics ; Humans ; Mutagenesis/genetics ; Oncogene Proteins/genetics ; Ovarian Neoplasms/drug therapy/*genetics ; P-Glycoprotein/genetics ; PTEN Phosphohydrolase/genetics ; Promoter Regions, Genetic/genetics ; Retinoblastoma Protein/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    ISSN:
    0006-3002
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0006-3002(56)90283-9

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0304-4165
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0304-4165(56)90283-5

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    1432-1076
    Keywords:
    Key wordsEnterococcus faecium ; Vancomycin resistance ; Colonisation ; Infection control
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract In order to determine the extent of vancomycin resistant enterococcus (VRE) colonisation within a paediatric oncology unit, the risk factors for the acquisition of the organism, the molecular epidemiology of the isolates and the impact of infection control measures, extensive patient and environmental surveillance was undertaken with identification, antibiotic susceptibility testing and pulsed-field gel electrophoresis (PFGE) of all VRE isolates. A matched case control study was carried out. Fourteen patients (19% of screened patients) with VRE colonisation were identified (12 with Enterococcus faecium). All isolates manifested the Van A phenotype. Extensive environmental contamination with VRE was present. PFGE of E. faecium isolates from 10 patients and from five of six environmental cultures revealed patterns suggesting genetic relatedness. Following comparison of the 14 cases with 41 controls matched for age (±4 years) and cohabitation on the oncology unit, risk factors for colonisation with VRE included duration of neutropenia, (OR, 3.72; 95% CI, 1.0–13.1), and antibiotic therapy, (OR, 4.07; 95% CI, 1.08–15.3), the number of antibiotic agents received, (OR, 8.4; 95% CI, 1.34–34.3) and the duration of therapy with amikacin, (OR, 10.7; 95% CI, 1.4–81.5), ceftazidime, (OR, 11.5; 95% CI, 2.2–59.9) or teicoplanin, (OR, 12.3; 95% CI, 2.25–67.4). Implementation of stringent infection control measures reduced environmental contamination from 25% of samples in week 1 to none in week 11. Two additional colonised patients were identified during the subsequent 6 months. Conclusion Risk factors for VRE colonization in paediatric oncology patients included duration of neutropenia, duration of any antibiotic therapy, exposure to ceftazidime, amikacin or teicoplanin and the number of antibiotics used. The study suggests that environmental contamination played an important role in patient-to-patient transmission of VRE and interventions including implementation of infection control measures were associated with a decreased incidence of gastro-intestinal colonisation.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004310050760

    Articles: DFG German National Licenses