Search Results - (Author, Cooperation:C. Mahon)
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1Uslaner, J. M., Kuduk, S. D., Wittmann, M., Lange, H. S., Fox, S. V., Min, C., Pajkovic, N., Harris, D., Cilissen, C., Mahon, C., Mostoller, K., Warrington, S., Beshore, D. C.
The American Society for Pharmacology and Experimental Therapeutics
Published 2018Staff ViewPublication Date: 2018-05-05Publisher: The American Society for Pharmacology and Experimental TherapeuticsPrint ISSN: 0022-3565Electronic ISSN: 1521-0103Topics: MedicinePublished by: -
2Staff View
Publication Date: 2018-01-14Publisher: Wiley-BlackwellPrint ISSN: 0007-0963Electronic ISSN: 1365-2133Topics: MedicinePublished by: -
3S. Jager ; D. Y. Kim ; J. F. Hultquist ; K. Shindo ; R. S. LaRue ; E. Kwon ; M. Li ; B. D. Anderson ; L. Yen ; D. Stanley ; C. Mahon ; J. Kane ; K. Franks-Skiba ; P. Cimermancic ; A. Burlingame ; A. Sali ; C. S. Craik ; R. S. Harris ; J. D. Gross ; N. J. Krogan
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-12-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Affinity Labels ; Animals ; Core Binding Factor beta Subunit/*metabolism ; Cullin Proteins/metabolism ; Cytidine Deaminase/*metabolism ; Gene Knockdown Techniques ; Gene Products, vif/*metabolism ; Genetic Complementation Test ; HEK293 Cells ; HIV Infections/*metabolism/*virology ; HIV-1/*physiology ; Host-Pathogen Interactions ; Humans ; Jurkat Cells ; Macaca mulatta/metabolism/virology ; Mass Spectrometry ; Models, Biological ; Protein Binding ; Proteolysis ; Simian Immunodeficiency Virus/metabolism ; Ubiquitin-Protein Ligases/chemistry/metabolism ; Ubiquitination ; Virus Replication ; vif Gene Products, Human Immunodeficiency Virus/*metabolismPublished by: -
4S. Jager ; P. Cimermancic ; N. Gulbahce ; J. R. Johnson ; K. E. McGovern ; S. C. Clarke ; M. Shales ; G. Mercenne ; L. Pache ; K. Li ; H. Hernandez ; G. M. Jang ; S. L. Roth ; E. Akiva ; J. Marlett ; M. Stephens ; I. D'Orso ; J. Fernandes ; M. Fahey ; C. Mahon ; A. J. O'Donoghue ; A. Todorovic ; J. H. Morris ; D. A. Maltby ; T. Alber ; G. Cagney ; F. D. Bushman ; J. A. Young ; S. K. Chanda ; W. I. Sundquist ; T. Kortemme ; R. D. Hernandez ; C. S. Craik ; A. Burlingame ; A. Sali ; A. D. Frankel ; N. J. Krogan
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-12-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Affinity Labels ; Amino Acid Sequence ; Conserved Sequence ; Eukaryotic Initiation Factor-3/chemistry/metabolism ; HEK293 Cells ; HIV Infections/metabolism/virology ; HIV Protease/metabolism ; HIV-1/*chemistry/*metabolism/physiology ; *Host-Pathogen Interactions ; Human Immunodeficiency Virus Proteins/analysis/chemistry/isolation & ; purification/*metabolism ; Humans ; Immunoprecipitation ; Jurkat Cells ; Mass Spectrometry ; Protein Binding ; Protein Interaction Mapping/*methods ; Protein Interaction Maps/*physiology ; Reproducibility of Results ; Virus ReplicationPublished by: -
5Scott, J. W. ; Thibeault, B. J. ; Mahon, C. J. ; Coldren, L. A. ; Peters, F. H.
Woodbury, NY : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: A very high current modulation efficiency of 5.7 GHz/(square root of)(mA) has been demonstrated in a low threshold (0.85 mA) InGaAs vertical-cavity surface-emitting laser. These top surface emission devices have been fabricated with intracavity contacts on semi-insulating substrates to realize their high speed potential. Data is presented for various laser diameters. Modulation bandwidths up to 9.3 GHz at a bias of only 4.5 mA have been measured for 7 μm diameter lasers. Derived parameters indicate that considerably higher bandwidths should be possible with better heat dissipation and modified cavity designs.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1572-817XSource: Springer Online Journal Archives 1860-2000Topics: Electrical Engineering, Measurement and Control TechnologyPhysicsNotes: Abstract Free-space ‘smart-pixel’ optical interconnect architectures promise to relieve the interconnect ‘bottleneck’ in high-speed parallel computers and switching systems. One of the most promising output devices that has been advanced for use in these systems is the asymmetric Fabry-Perot modulator, or AFPM, which offers high on-off contrast, low insertion loss, and low operating voltage swing, among other advantages. In this paper we summarize our work on optimizing the AFPM for high-speed operation, including analysis of the material structure design considerations, fabrication of small (16×20 μm) devices, and high-speed electrical and optical characterization of the finished modulators. We conclude that at relatively high incident optical intensities the modulators' speed appears to be limited by transit effects to about 18 GHz, but that at lower optical intensities their frequency response outstrips that of our 20 GHz measurement apparatus — that is, these AFPMs are still capable of large signal modulation (20 dB contrast, 1.5 dB insertion loss) at low AC voltage swings (±3 V) for operating frequencies up to 20 GHz. We presume that further investigation will prove them to be RC-limited in this low-intensity regime to speeds of about 35 GHz.Type of Medium: Electronic ResourceURL: