Search Results - (Author, Cooperation:C. L. Smith)
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1H. C. Aoudjehane ; G. Avice ; J. A. Barrat ; O. Boudouma ; G. Chen ; M. J. Duke ; I. A. Franchi ; J. Gattacceca ; M. M. Grady ; R. C. Greenwood ; C. D. Herd ; R. Hewins ; A. Jambon ; B. Marty ; P. Rochette ; C. L. Smith ; V. Sautter ; A. Verchovsky ; P. Weber ; B. Zanda
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-10-16Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Carbon Isotopes/analysis ; Iron Compounds/analysis ; Magnesium Compounds/analysis ; *Mars ; *Meteoroids ; Nitrogen Isotopes/analysis ; Oxygen Isotopes/analysis ; Silicates/analysisPublished by: -
2Y. Li ; N. T. Klena ; G. C. Gabriel ; X. Liu ; A. J. Kim ; K. Lemke ; Y. Chen ; B. Chatterjee ; W. Devine ; R. R. Damerla ; C. Chang ; H. Yagi ; J. T. San Agustin ; M. Thahir ; S. Anderton ; C. Lawhead ; A. Vescovi ; H. Pratt ; J. Morgan ; L. Haynes ; C. L. Smith ; J. T. Eppig ; L. Reinholdt ; R. Francis ; L. Leatherbury ; M. K. Ganapathiraju ; K. Tobita ; G. J. Pazour ; C. W. Lo
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-03-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cilia/genetics/*pathology/physiology/ultrasonography ; DNA Mutational Analysis ; Electrocardiography ; Exome/genetics ; Genes, Recessive ; Genetic Testing ; Heart Defects, Congenital/*genetics/*pathology/ultrasonography ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mutation/genetics ; Signal TransductionPublished by: -
3A. Valouev ; S. M. Johnson ; S. D. Boyd ; C. L. Smith ; A. Z. Fire ; A. Sidow
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-05-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Cells, Cultured ; Chromatin Assembly and Disassembly/*physiology ; *Gene Expression Regulation ; Genome, Human/genetics ; Granulocytes/metabolism ; High-Throughput Nucleotide Sequencing ; Humans ; Micrococcal Nuclease/metabolism ; Nucleosomes/chemistry/genetics/*metabolism ; Organ Specificity ; Transcription, GeneticPublished by: -
4K. Song ; Y. J. Nam ; X. Luo ; X. Qi ; W. Tan ; G. N. Huang ; A. Acharya ; C. L. Smith ; M. D. Tallquist ; E. G. Neilson ; J. A. Hill ; R. Bassel-Duby ; E. N. Olson
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics/metabolism ; Cell Lineage ; *Cell Transdifferentiation ; *Cellular Reprogramming ; Fibroblasts/*cytology/physiology ; Heart/*physiology/physiopathology ; Mice ; Myocardial Infarction/pathology/physiopathology/*therapy ; Myocardium/cytology/pathology ; Myocytes, Cardiac/*cytology/physiology ; Phenotype ; Regenerative Medicine/methods ; S100 Proteins/genetics/metabolism ; Tail/cytology ; Transcription Factors/genetics/*metabolismPublished by: -
5Staff View
Publication Date: 2018-06-06Publisher: BMJ Publishing GroupTopics: MedicinePublished by: -
6Staff View
Type of Medium: articlePublication Date: 2003Keywords: Spende ; Hochschulfinanzierung ; USAIn: Economics of education review, Bd. 22 (2003) H. 3, S. 223-235, 0272-7757Language: English -
7Cassata, W. S., Cohen, B. E., Mark, D. F., Trappitsch, R., Crow, C. A., Wimpenny, J., Lee, M. R., Smith, C. L.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-05-24Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
8Staff View
Publication Date: 2018-06-08Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Geochemistry, Geophysics, Planetary SciencePublished by: -
9Staff View
ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The case is described of a patient who underwent artificial ventilation in an intensive therapy unit and received an infusion of alcuronium 10 mg/hour for more than 4 days, in the presence of significant renal (and later, some degree of hepatic) impairment. Prolonged and profound neuromuscular block persisted despite haemodialysis (5 hours on each of 3 days) followed by 72 hours of continuous haemofiltration; it appeared to resolve only after plasma exchange (4 litres). The total period of persistent block, for 9 days after the infusion had been stopped, is thought to be the longest period ever reported after administration of alcuronium. Neuromuscular block was monitored throughout this period using the train-of-four twitch technique. The potentiating effects of concurrent aminoglycoside therapy and hepatic dysfunction on the degree of paralysis are discussed.Type of Medium: Electronic ResourceURL: -
11RUSSELL, G. N. ; SMITH, C. L. ; SNOWDON, S. L. ; BRYSON, T. H. L.
Oxford, UK : Blackwell Publishing Ltd
Published 1987Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The effects of pre-oxygenation were studied by continuous expired oxygen analysis in twenty pregnant patients and ten nonpregnant controls. The Magill system and a demand valve breathing system were both studied with tidal and vital capacity breathing. Rapid pre-oxygenation was possible with the demand valve system but the technique was associated with air leaks around the mask. Vital capacity breathing with the Magill system was inefficient in practice because of rebreathing and air leaks, and the recently proposed four vital capacity breath technique provided suboptimal alveolar oxygenation in pregnant subjects. Oxygenation in pregnant subjects was significantly faster than in nonpregnant controls and was achieved after just 2 minutes of tidal breathing from a standard Magill system with a prefilled reservoir. Care was necessary to ensure a gas-tight seal around the facemask.Type of Medium: Electronic ResourceURL: -
12ARALA-CHAVHS, M. P. ; KORN, J. H. ; GALBRAITH, G. M. P. ; PORTO, M. T. ; SMITH, C. L. ; FUDENBFRG, H. H.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We have studied two patients with common variable immunodeficiency (CVID) impaired cell-mediated immunity. and high percentages of monocytes in their peripheral blood. Removal of monocytes from cultures of peripheral blood mononuclear cells from both patients increased the in vilro responses to phytohaemagglutinin (PHA) and concanavalin A (Con A) but not to purified protein derivative (PPD), as measured by [3H]thymidine uptake. Similarly, supernatants of monocyte cultures from both patients. unlike supernatants of normal monocytes, suppressed the in vitro responses to PHA and Con A but enhanced the response to PPD by cultured mononuclear cells from the patients and from normal donors. Addition of unfractionaicd mononuclear cells from both patients 10 normal mononuclear cells suppressed both pokeweed mitogen (PWM) stimulation and IgG production: this effect was abrogated by removal of monocytes from the patients’ mono-nuclear cell populations. The effect of thymosin on both patients’ mononuclear cells was assayed in vitro. Thymosin was ineffective in vitro with cells from the first patient: for the other patient. [3H]thymidine uptake by mononuclear cells stimulated with PPD increased. whereas uptake by Con A-stimulated cells decreased, as did the percentage of E rosette-forming cells, providing further evidence of heterogeneity of the CVID syndrome. The effects of thymosin were also dependent on monocytes.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Anaesthetic management of a patient with glucose-6-phosphate dehydrogenase deficiency is described. The pathogenesis and various complications relating to this common hereditary blood disorder are reviewed. Problems related to anaesthesia in the presence of glucose-6-phosphate dehydrogenase deficiency are discussed.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The use of an infusion of vecuronium is described in seven patients with renal and respiratory failure in an intensive therapy unit. Neuromuscular function was monitored throughout using the train-of-four twitch technique. A bolus dose of vecuronium (0.1 mg/kg) was given, followed immediately by a continuous infusion (0.05 mg/kg/hour). The infusion rate was adjusted until the first twitch of the train was helow 20% of control and then run at a constant rate.There was a marked variation in the dose of vecuronium administered (0.01—0.65 mg/kg/hour). Two patients, who appeared to be most sensitive to the drug, were both receiving metronidazole. Recovery of neuromuscular function was extremely prolongea and widely variable (6–37 hours) on stopping the infusion. No adverse cardiovascular effects or evidence of histamine release were seen as a result of administration of the drug. Vecuronium is probably more suitable for administration in bolus doses rather than by infusion in patients with renal and respiratory failure.Type of Medium: Electronic ResourceURL: -
15Losowsky, M. S. ; Kelleher, J. ; Walker, B. E. ; Davies, T. ; Smith, C. L.
Oxford, UK : Blackwell Publishing Ltd
Published 1972Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Sometimes relatively low values were found in November and unexpectedly high concentrations in October. Some of these samples had been kept for three to five days in a tank-room at approximately atmospheric temperature, while others were actually killed in the field and the livers frozen in solid ...Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] There was no change in the mean blood-sugar level in the first 1 £ hr. after insulin (23 ± 1-81 mgm./100 ml.), but after 5 hr. it had fallen to a very low value (3 ± 0-69 mgm./100 ml.), which was maintained to the end of the experiments when the frogs had shown typical insulin ...Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] BECAUSE of their phylogenetic position and varying degrees of adaptation to life in two media the Amphibia are a group with which comparative physiologists are rightly very much concerned. In this, the presumably final, volume of Physiology of the Amphibia, the somewhat scattered literature in ...Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Nalidixic acid, novobiocin and coumermycin specifically inhibit phage promoter-dependent transcription of the trp operon in Φ80ptrp but not transcription from the authentic trp promoter. The nalidixic acid inhibition is not observed in an E. coli strain containing a nalAr ...Type of Medium: Electronic ResourceURL: -
20NEWTON, ALISON ; DENDY, P. P. ; SMITH, C. L. ; WILDY, P.
[s.l.] : Nature Publishing Group
Published 1962Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] In a set of experiments designed to investigate variations in the amount of deoxyribonucleic acid (DNA) per HeLa cell during the course of infection with herpes virus, which have been described in detail elsewhere2, we have obtained similar results which can be attributed to a marked variation in ...Type of Medium: Electronic ResourceURL: