Search Results - (Author, Cooperation:C. Joseph)

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  1. 1
    Butts, Robert E. ; Pitt, Joseph C.
    Dordrecht : D. Reidel
    Published 1978
    Staff View Availability
    Person(s):
    Butts, Robert E.; Pitt, Joseph C.
    Type of Medium:
    Unknown
    Pages:
    262 S.
    Printed Books
  2. 2
    V. Kumar ; K. Kim ; C. Joseph ; S. Kourrich ; S. H. Yoo ; H. C. Huang ; M. H. Vitaterna ; F. P. de Villena ; G. Churchill ; A. Bonci ; J. S. Takahashi
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-12-21
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Substitution ; Animals ; Central Nervous System Stimulants/administration & dosage ; Cocaine/*administration & dosage ; Cocaine-Related Disorders/*genetics/*psychology ; *Drug-Seeking Behavior ; Methamphetamine/administration & dosage ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Motor Activity/drug effects ; Mutation ; Nerve Tissue Proteins/genetics/*physiology ; Phenylalanine/genetics ; Polymorphism, Single Nucleotide ; Psychomotor Performance/drug effects ; Quantitative Trait Loci ; Serine/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Burns, Jacqueline K. ; Lewandowski, Dennis J. ; Nairn, C. Joseph ; Brown, G. E.

    Copenhagen : Munksgaard International Publishers
    Published 1998
    Staff View
    ISSN:
    1399-3054
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    The physiological and molecular events of ethylene-induced abscission in mature fruit calyx, laminar and floral abscission zones of cv. Valencia orange were examined. Continuous exposure of fruit explants to 5 µl 1−1 ethylene for 2 to 40 h resulted in marked increases in endo-1,4-β-glucanase (cellulase) and polygalacturonase (PG) activities in calyx abscission zones. Two abscission-related cellulases and one PG were found. The major peak of cellulase activity corresponded to a pI of 8.0 and molecular weight of 51 kDa, whereas the minor cellulase peak had a pI of 5.5. The abscission polygalacturonase had a pI of 5.5. Calyx abscission zone RNA was amplified with degenerate primers based on sequence of the purified Valencia orange calyx abscission cellulase, and cloned. The two partial cellulase cDNA clones were 59% identical at the nucleotide level. Genomic Southern analysis suggested that Valencia orange contained two groups of cellulase genes. A full-length cDNA clone from each group was isolated from a cDNA library prepared from ethylene-induced calyx abscission zone mRNA. Both genes were expressed in ethylene-induced calyx, laminar and floral abscission zones, but were not expressed in non-induced abscission zones or mature leaves treated with or without ethylene, young bark or young fruit of Valencia.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1572-8838
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Electrical Engineering, Measurement and Control Technology
    Notes:
    Abstract The heterogeneous catalytic redox behaviour of a titanium dioxide coated titanium electrode surface was investigated with and without o-nitrophenol using cyclic voltammetry. A comparison of the cyclic voltammograms recorded in the absence and in the presence of o-nitrophenol confirmed the catalytic reduction of o-nitrophenol by the surface Ti4+/Ti3+ redox system present on the electrode surface. Preparative scale experiments were also carried out using a Ti/TiO2 electrode of large surface area and the redox behaviour of the electrode was confirmed by the isolation of o-aminophenol with high current efficiency and yield.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
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    Nuesse, C. Joseph

    Washington : Periodicals Archive Online (PAO)
    Published 1991
    Staff View
    ISSN:
    0008-8080
    Topics:
    History
    Theology and Religious Studies
    Description / Table of Contents:
    American
    Notes:
    BOOK REVIEWS
    URL:
    Articles: DFG German National Licenses
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    PALAMOUNTAIN, C. JOSEPH

    Yellow Springs, Ohio : Periodicals Archive Online (PAO)
    Published 1966
    Articles: DFG German National Licenses
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    Nuesse, C. Joseph

    New Haven, Conn., etc. : Periodicals Archive Online (PAO)
    Published 1966
    Staff View
    ISSN:
    0034-4087
    Topics:
    Theology and Religious Studies
    Notes:
    Symposium: Religious Education in the Secular City
    URL:
    Articles: DFG German National Licenses
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    Staff View
    ISSN:
    1432-0843
    Keywords:
    Key words Antineoplastic agents ; Toxicity tests ; Toxicology ; Guidelines ; Phase I clinical trials
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract The entry of new anticancer treatments into phase I clinical trials is ordinarily based on relatively modest preclinical data. This report defines the battery of preclinical tests important for assessing safety under an Investigational New Drug application (IND) and outlines a basis for extrapolating starting doses of investigational anticancer drugs in phase I clinical trials from animal toxicity studies. Types of preclinical studies for the support of marketing of a new anticancer drug are also discussed. This report addresses differences and similarities in the preclinical development of cytotoxic drugs (including photosensitizers and targeted delivery products), drugs used chronically (chemopreventive drugs, hormonal drugs, immunomodulators), and drugs intended to enhance the efficacy (MDR-reversing agents and radiation/chemotherapy sensitizers) or diminish the toxicity of currently used anticancer therapies. Factors to consider in the design of preclinical studies of combination therapies, alternative therapies, and adjuvant therapies in the treatment of cancer, and to support changes in clinical formulations or route of administration, are also discussed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses