Search Results - (Author, Cooperation:C. Joseph)
-
1Staff View Availability
Person(s): Butts, Robert E.; Pitt, Joseph C.Type of Medium: UnknownPages: 262 S. -
2V. Kumar ; K. Kim ; C. Joseph ; S. Kourrich ; S. H. Yoo ; H. C. Huang ; M. H. Vitaterna ; F. P. de Villena ; G. Churchill ; A. Bonci ; J. S. Takahashi
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-12-21Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Substitution ; Animals ; Central Nervous System Stimulants/administration & dosage ; Cocaine/*administration & dosage ; Cocaine-Related Disorders/*genetics/*psychology ; *Drug-Seeking Behavior ; Methamphetamine/administration & dosage ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Motor Activity/drug effects ; Mutation ; Nerve Tissue Proteins/genetics/*physiology ; Phenylalanine/genetics ; Polymorphism, Single Nucleotide ; Psychomotor Performance/drug effects ; Quantitative Trait Loci ; Serine/geneticsPublished by: -
3Burns, Jacqueline K. ; Lewandowski, Dennis J. ; Nairn, C. Joseph ; Brown, G. E.
Copenhagen : Munksgaard International Publishers
Published 1998Staff ViewISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: The physiological and molecular events of ethylene-induced abscission in mature fruit calyx, laminar and floral abscission zones of cv. Valencia orange were examined. Continuous exposure of fruit explants to 5 µl 1−1 ethylene for 2 to 40 h resulted in marked increases in endo-1,4-β-glucanase (cellulase) and polygalacturonase (PG) activities in calyx abscission zones. Two abscission-related cellulases and one PG were found. The major peak of cellulase activity corresponded to a pI of 8.0 and molecular weight of 51 kDa, whereas the minor cellulase peak had a pI of 5.5. The abscission polygalacturonase had a pI of 5.5. Calyx abscission zone RNA was amplified with degenerate primers based on sequence of the purified Valencia orange calyx abscission cellulase, and cloned. The two partial cellulase cDNA clones were 59% identical at the nucleotide level. Genomic Southern analysis suggested that Valencia orange contained two groups of cellulase genes. A full-length cDNA clone from each group was isolated from a cDNA library prepared from ethylene-induced calyx abscission zone mRNA. Both genes were expressed in ethylene-induced calyx, laminar and floral abscission zones, but were not expressed in non-induced abscission zones or mature leaves treated with or without ethylene, young bark or young fruit of Valencia.Type of Medium: Electronic ResourceURL: -
4Ravichandran, C. ; Kennady, C. Joseph ; Chellammal, S. ; Thangavelu, S. ; Anantharaman, P. N.
Springer
Published 1991Staff ViewISSN: 1572-8838Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyElectrical Engineering, Measurement and Control TechnologyNotes: Abstract The heterogeneous catalytic redox behaviour of a titanium dioxide coated titanium electrode surface was investigated with and without o-nitrophenol using cyclic voltammetry. A comparison of the cyclic voltammograms recorded in the absence and in the presence of o-nitrophenol confirmed the catalytic reduction of o-nitrophenol by the surface Ti4+/Ti3+ redox system present on the electrode surface. Preparative scale experiments were also carried out using a Ti/TiO2 electrode of large surface area and the redox behaviour of the electrode was confirmed by the isolation of o-aminophenol with high current efficiency and yield.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0008-8080Topics: HistoryTheology and Religious StudiesNotes: BOOK REVIEWSURL: -
6Staff View
ISSN: 0008-8080Topics: HistoryTheology and Religious StudiesNotes: BOOK REVIEWSURL: -
7Staff View
ISSN: 0008-8080Topics: HistoryTheology and Religious StudiesURL: -
8Staff View
ISSN: 0008-8080Topics: HistoryTheology and Religious StudiesDescription / Table of Contents: AmericanNotes: BOOK REVIEWSURL: -
9Staff View
ISSN: 0022-2429Topics: EconomicsURL: -
10Staff View
ISSN: 0022-2429Topics: EconomicsURL: -
11Staff View
ISSN: 0003-5769Topics: English, American StudiesNotes: SPECIAL SECTIONURL: -
12Staff View
ISSN: 0007-6805Topics: HistoryEconomicsURL: -
13Staff View
ISSN: 0007-6805Topics: HistoryEconomicsNotes: BOOK REVIEWSURL: -
14Staff View
ISSN: 0007-6805Topics: HistoryEconomicsNotes: BOOK REVIEWSURL: -
15Staff View
ISSN: 0007-6805Topics: HistoryEconomicsNotes: "BOOK REVIEWS"URL: -
16Staff View
ISSN: 0007-6805Topics: HistoryEconomicsNotes: BOOK REVIEWSURL: -
17Staff View
ISSN: 0007-6805Topics: HistoryEconomicsNotes: BOOK REVIEWSURL: -
18Staff View
ISSN: 0034-4087Topics: Theology and Religious StudiesNotes: Symposium: Religious Education in the Secular CityURL: -
19Staff View
ISSN: 0037-7996Topics: HistoryURL: -
20DeGeorge, Joseph J. ; Ahn, Chang-Ho ; Andrews, Paul A. ; Brower, Margaret E. ; Giorgio, Diana W. ; Goheer, M. Anwar ; Lee-Ham, Doo Y. ; McGuinn, W. David ; Schmidt, Wendelyn ; Sun, C. Joseph ; Tripathi, Satish C.
Springer
Published 1997Staff ViewISSN: 1432-0843Keywords: Key words Antineoplastic agents ; Toxicity tests ; Toxicology ; Guidelines ; Phase I clinical trialsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The entry of new anticancer treatments into phase I clinical trials is ordinarily based on relatively modest preclinical data. This report defines the battery of preclinical tests important for assessing safety under an Investigational New Drug application (IND) and outlines a basis for extrapolating starting doses of investigational anticancer drugs in phase I clinical trials from animal toxicity studies. Types of preclinical studies for the support of marketing of a new anticancer drug are also discussed. This report addresses differences and similarities in the preclinical development of cytotoxic drugs (including photosensitizers and targeted delivery products), drugs used chronically (chemopreventive drugs, hormonal drugs, immunomodulators), and drugs intended to enhance the efficacy (MDR-reversing agents and radiation/chemotherapy sensitizers) or diminish the toxicity of currently used anticancer therapies. Factors to consider in the design of preclinical studies of combination therapies, alternative therapies, and adjuvant therapies in the treatment of cancer, and to support changes in clinical formulations or route of administration, are also discussed.Type of Medium: Electronic ResourceURL: