Search Results - (Author, Cooperation:C. J. Lin)
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1Lai, H.-C., Chang, C.-J., Lin, C.-S., Wu, T.-R., Hsu, Y.-J., Wu, T.-S., Lu, J.-J., Martel, J., Ojcius, D. M., Ku, C.-L., Young, J. D., Lu, C.-C.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-08-21Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
2J. L. Van Nostrand ; C. A. Brady ; H. Jung ; D. R. Fuentes ; M. M. Kozak ; T. M. Johnson ; C. Y. Lin ; C. J. Lin ; D. L. Swiderski ; H. Vogel ; J. A. Bernstein ; T. Attie-Bitach ; C. P. Chang ; J. Wysocka ; D. M. Martin ; L. D. Attardi
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Abnormalities, Multiple/genetics/*metabolism ; Alleles ; Animals ; Apoptosis/genetics ; CHARGE Syndrome/*genetics/*metabolism ; Cell Cycle Checkpoints/genetics ; Craniofacial Abnormalities/genetics/metabolism ; DNA-Binding Proteins/deficiency/genetics/metabolism ; Ear/abnormalities ; Embryo, Mammalian/abnormalities/metabolism ; Female ; Fibroblasts ; Gene Deletion ; Heterozygote ; Humans ; Male ; Mice ; Mutant Proteins/metabolism ; *Phenotype ; Promoter Regions, Genetic/genetics ; Tumor Suppressor Protein p53/*genetics/*metabolismPublished by: -
3P. Han ; W. Li ; C. H. Lin ; J. Yang ; C. Shang ; S. T. Nurnberg ; K. K. Jin ; W. Xu ; C. Y. Lin ; C. J. Lin ; Y. Xiong ; H. C. Chien ; B. Zhou ; E. Ashley ; D. Bernstein ; P. S. Chen ; H. S. Chen ; T. Quertermous ; C. P. Chang
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cardiac Myosins/genetics ; Cardiomegaly/*genetics/*pathology/prevention & control ; Cardiomyopathies/genetics/pathology/prevention & control ; Chromatin/genetics/metabolism ; Chromatin Assembly and Disassembly ; DNA Helicases/antagonists & inhibitors/chemistry/genetics/metabolism ; Feedback, Physiological ; Heart Failure/genetics/pathology/prevention & control ; Histone Deacetylases/metabolism ; Humans ; Mice ; Myocardium/metabolism/pathology ; Myosin Heavy Chains/*genetics ; Nuclear Proteins/antagonists & inhibitors/chemistry/genetics/metabolism ; Organ Specificity ; Poly(ADP-ribose) Polymerases/metabolism ; Protein Binding ; Protein Structure, Tertiary ; RNA, Long Noncoding/antagonists & inhibitors/*genetics/metabolism ; Transcription Factors/antagonists & inhibitors/chemistry/genetics/metabolismPublished by: -
4Staff View
Publication Date: 2018-02-03Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
5D. W. Parsons ; M. Li ; X. Zhang ; S. Jones ; R. J. Leary ; J. C. Lin ; S. M. Boca ; H. Carter ; J. Samayoa ; C. Bettegowda ; G. L. Gallia ; G. I. Jallo ; Z. A. Binder ; Y. Nikolsky ; J. Hartigan ; D. R. Smith ; D. S. Gerhard ; D. W. Fults ; S. VandenBerg ; M. S. Berger ; S. K. Marie ; S. M. Shinjo ; C. Clara ; P. C. Phillips ; J. E. Minturn ; J. A. Biegel ; A. R. Judkins ; A. C. Resnick ; P. B. Storm ; T. Curran ; Y. He ; B. A. Rasheed ; H. S. Friedman ; S. T. Keir ; R. McLendon ; P. A. Northcott ; M. D. Taylor ; P. C. Burger ; G. J. Riggins ; R. Karchin ; G. Parmigiani ; D. D. Bigner ; H. Yan ; N. Papadopoulos ; B. Vogelstein ; K. W. Kinzler ; V. E. Velculescu
American Association for the Advancement of Science (AAAS)
Published 2010Staff ViewPublication Date: 2010-12-18Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Cerebellar Neoplasms/*genetics/metabolism ; Child ; DNA Copy Number Variations ; DNA-Binding Proteins/genetics/metabolism ; *Genes, Neoplasm ; Genes, Tumor Suppressor ; Histone-Lysine N-Methyltransferase/genetics/metabolism ; Histones/metabolism ; Humans ; Medulloblastoma/*genetics/metabolism ; Methylation ; MicroRNAs/genetics ; *Mutation ; Neoplasm Proteins/genetics/metabolism ; Oligonucleotide Array Sequence Analysis ; Point Mutation ; Sequence Analysis, DNA ; Signal TransductionPublished by: -
6Staff View
Publication Date: 2018-02-03Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
7J. Vadas, Varinderjit Singh, B. B. Wiggins, J. Huston, S. Hudan, R. T. de; Souza, Z. Lin, C. J. Horowitz, A. Chbihi, D. Ackermann, M. Famiano, and K. W. Brown
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-03-28Publisher: American Physical Society (APS)Print ISSN: 0556-2813Electronic ISSN: 1089-490XTopics: PhysicsKeywords: Nuclear ReactionsPublished by: -
8Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Co/Pt multilayers with large Kerr rotations at short wavelengths and the magnetic and material properties desired for magneto-optical (MO) recording have been studied extensively as potential future MO materials. Very good recording performance has been demonstrated.1 However, the typical constituent layers in Co/Pt multilayers are very thin, 0.2–0.4 nm Co layers and about 1 nm/Pt layers. To manufacture Co/Pt multilayers consisting of 10–30 periods of such thin Co and Pt layers is certainly quite a challenge. One would prefer to deal with CoPt alloys if the alloys can be made to have large perpendicular magnetic anisotropy and coercivity. Previously no one was able to directly deposit CoPt alloy films with large perpendicular magnetic anisotropy and saturated remanence. Here we will demonstrate for the first time that CoPt alloy films with large perpendicular magnetic anisotropy and coercivity, and saturated remanence can be directly deposited by e-beam evaporation onto heated substrates, at 200 °C or above. Furthermore, we will demonstrate that the perpendicular magnetic anisotropy of CoPt alloy films can be dramatically enhanced by well (111)-textured Pt underlayers. The key to this success appears to be in controlling the crystallographic orientation of these alloy films such that the CoPt(111) lattice plane is parallel to the film surface. CoPt alloys with wide composition range, e.g., 25–57 at. % Co, have been obtained with saturated perpendicular magnetic remanence, indicating that the perpendicular magnetic anisotropy obtained in these alloy films is not related to the ordered tetragonal Co50Pt50 phase. Further work, however, is needed to clarify the anisotropy mechanism in these CoPt alloy films.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The basic requirements for achieving direct overwrite in magneto-optic recording are discussed from the basic physics of localized magnetization reversal during thermomagnetic recording. The operating principles and the key issues are reviewed and critically assessed for several major direct overwrite approaches including beam modulation using single-layer media, beam modulation using exchange-coupled multilayers, and magnetic field modulation.Type of Medium: Electronic ResourceURL: -
10Yao, Y. D. ; Chen, Y. Y. ; Chuang, T. H. ; Kung, C. ; Lin, C. J.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The variations of the electrical resistivity, the magnetization, and the grain-boundary precipitates of a Ni-rich Ni-In alloy system with In concentration up to 7.5 at. % have been investigated as functions of annealing time at 773 K. For samples homogenized at 1225 K, clear grain boundaries are observed. However, for these aged samples, we observed both grain-boundary precipitates and variations of the electrical resistivity and the magnetization; and the binary alloy with higher In concentration has the higher variation rate in the decrease of the electrical resistivity, the increase of the magnetization, and the growth of the grain-boundary precipitates.Type of Medium: Electronic ResourceURL: -
11Hermsmeier, B. D. ; Farrow, R. F. C. ; Lee, C. H. ; Marinero, E. E. ; Lin, C. J. ; Marks, R. F. ; Chien, C. J.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: In this paper we report the molecular-beam epitaxial growth of Co/Pt superlattices on epitaxial Ag films on GaAs substrates. The growth axis of the superlattice was selected by seeded epitaxy to be along either the [001], [110], or [111] axis of Pt. The magnetic properties of the superlattices depend on the orientation of the growth axis. In situ x-ray photoelectron diffraction studies of the Co-Pt interfaces during their formation reveals that they are not atomically abrupt for any of the orientations. We conclude that models for magnetic anisotropy of Co/Pt superlattices should be based on a combination of magnetocrystalline anisotropy and strain in compositionally mixed interfaces.Type of Medium: Electronic ResourceURL: -
12Grütter, P. ; Rugar, D. ; Mamin, H. J. ; Castillo, G. ; Lin, C.-J. ; McFadyen, I. R. ; Valletta, R. M. ; Wolter, O. ; Bayer, T. ; Greschner, J.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: In this paper the properties of force sensors suitable for magnetic force microscopy (MFM) made by coating silicon microcantilevers with various thin magnetic films are analyzed. These MFM force sensors are batch fabricated and their magnetic properties controlled by choosing appropriate coatings. Theoretical calculations show that thin-film MFM tips have a significantly reduced stray field, a good signal-to-noise ratio, and yield improved resolution when compared to etched wire tips. The sample perturbation due to the tip stray field is small, allowing the imaging of low-coercivity samples such as Permalloy.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: We have characterized an InGaP/InGaAsN/GaAs NpN double-heterojunction bipolar transistor structure using polarized photoreflectance (PR) spectroscopy. The ordering parameter of the InGaP is deduced from the polarization {[110] and [11¯0]} dependence of the PR signals from the emitter region. The ordering related piezoelectric field is also found to influence the electric field, as evaluated from observed Franz–Keldysh oscillations, in the InGaP emitter region. The field in the emitter region is found to be about 25 kV/cm smaller than the theoretical value that does not take into account the possible ordering induced screening effect, while the field in the collector region agrees well with the theoretical value. In addition, the InGaAsN band gap is also determined by analyzing the PR spectrum of the base region. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
14Rugar, D. ; Suits, J. C. ; Lin, C.-J.
Woodbury, NY : American Institute of Physics (AIP)
Published 1988Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: A method is described for thermomagnetic direct overwrite in amorphous Tb23 Fe77 . Using long (500 ns) laser pulses, micron-size domains can be written with diameters significantly smaller than the diameter of the Curie temperature isotherm. The relatively small domain size is due to the collapsing effect of the thermally generated domain wall energy gradient. Without switching the magnetic bias field, the domains can be collapsed to submicron size using short (50 ns) laser pulses. Domains can be completely erased by firing short pulses in succession as the recording medium is moved slowly with respect to the optical beam.Type of Medium: Electronic ResourceURL: -
15Grütter, P. ; Rugar, D. ; Mamin, H. J. ; Castillo, G. ; Lambert, S. E. ; Lin, C.-J. ; Valletta, R. M. ; Wolter, O. ; Bayer, T. ; Greschner, J.
Woodbury, NY : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: In this letter we describe force sensors suitable for magnetic force microscopy (MFM) made by coating silicon microcantilevers with various thin magnetic films. These MFM force sensors can be batch fabricated and their magnetic properties tailored by choosing appropriate coatings. This is demonstrated by analyzing the MFM response for magnetization patterns written on a longitudinal recording test sample. Selectable components of the sample stray field can be measured by coating the tips with high coercivity films. Tips coated with low coercivity films such as Permalloy respond to the total stray field. Sample perturbations due to the tip stray field are small for thin-film tips, allowing the imaging of low coercivity samples such as Permalloy.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Computer model calculations and experimental comparison are presented for thermomagnetic writing in TbFe media. Two models are discussed which are appropriate for two observed types of writing behavior. A "bubble'' type writing model is found to give good experimental agreement when wall motion processes dominate and the laser-written marks exhibit single-domain behavior. This model accurately accounts for the writing behavior of Tb0.23Fe0.77. The gradient of the domain-wall energy is found to be an important factor in the writing process and can cause nucleation to be delayed until some cooling has occurred. This results in written domain sizes which are a strong function of the applied bias field. For compositions which exhibit multiple domain writing behavior, a "nucleation field'' model is found to be appropriate. This model predicts the observed weak dependence of mark size on applied bias field. In addition, the nucleation field model is used to calculate the bias fields which correspond to the onset of writing (onset field) and single-domain mark formation (saturation field).Type of Medium: Electronic ResourceURL: -
17Suits, J. C. ; Geiss, R. H. ; Lin, C. J. ; Rugar, D. ; Bell, A. E.
[S.l.] : American Institute of Physics (AIP)
Published 1987Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: A review is given of Lorentz microscopy and its application to the study of laser-written domains in amorphous rare-earth/transition-metal–type materials. Domains, or regions of reverse magnetization, were written under various conditions of laser power and applied magnetic field in TbxFe1−x films where x varies in the range 0.14–0.32. Upon examination by Lorentz microscopy, and under certain conditions, these written regions show highly detailed magnetic structures. One condition for obtaining good images is the avoidance of oxidized surface layers showing in-plane magnetization. Another condition is tilting of the film plane in the transmission electron microscope to enhance image contrast. A variety of domain structures have been observed ranging from fully saturated regions with both highly regular and irregular boundaries, to fully demagnetized regions. An example of correlation between the field dependence of the microstructure and measurements of magneto-optical signal is given for the x=0.32 composition. Results are presented of carrier signal and noise measurements made on a film on a rotating disk.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Lorentz electron microscopy has been used to investigate the micromagnetic mechanism of M-H hysteresis loop behavior of thin amorphous TbFe films with perpendicular easy-axis magnetic anisotropy. Detailed nucleation and growth behavior of reverse domains was observed while an applied field provided by the microscope objective lens along the film normal was slowly changed. Very different results between Tb19Fe81 and Tb32Fe68 films have been observed. The reverse domain grew more or less radially in the former case, while a dendritelike domain pattern was observed for the latter case.Type of Medium: Electronic ResourceURL: -
19Weller, D. ; Brändle, H. ; Gorman, G. ; Lin, C.-J. ; Notarys, H.
Woodbury, NY : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Co1−xPtx alloys with Pt contents in the range 0.45≤x≤0.9 show sizable perpendicular magnetic anisotropy, 100% perpendicular remanence and coercivities in the range 160 kA/m. Thin films of this material are grown by electron beam evaporation onto fused silica or Si, at substrate temperatures between 150 and 350 °C. Spectroscopic investigations of the polar Kerr rotation show a significant enhancement of the Pt related UV peak. A comparison of the static signal levels R×(θk2+εk2)1/2 of Co/Pt multilayers and alloys shows an overall 50% enhancement in the case of alloys. Curie temperatures around 200 °C are observed for Co∼22Pt∼78 compositions. These properties, together with the potentially high chemical stability and ease of manufacturing make Co1−xPtx alloys very attractive materials for short wavelength magneto-optic recording.Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Very high carrier-to-noise ratios of 67 dB (30 kHz bandwidth) were achieved on magneto-optic recording disks that utilize two thin magneto-optic layers. This improvement came primarily from the reduction in the disk writing noise. We explain this noise reduction through the statistical averaging of the written magnetic transition positions in these two active layers. In principle the disk writing noise can be further reduced when more active layers are utilized in the disk structure.Type of Medium: Electronic ResourceURL: