Search Results - (Author, Cooperation:C. H. Ho)

2014-05-17

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Computer Science

Medicine

Natural Sciences in General

Physics

Arabidopsis/genetics/*metabolism ; Arabidopsis Proteins/genetics/*metabolism ; Cell Membrane/*metabolism ; Membrane Proteins/genetics/*metabolism ; *Protein Interaction Maps ; Signal Transduction ; Two-Hybrid System Techniques

2018-05-23

Nature Publishing Group (NPG)

2041-1723

Biology

Chemistry and Pharmacology

Natural Sciences in General

Physics

2014-05-13

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Amino Acid Sequence ; Catalytic Domain ; Conserved Sequence ; Eukaryota/classification/*enzymology ; Humans ; *Models, Molecular ; Oxygenases/*chemistry/metabolism ; Phylogeny ; Prokaryotic Cells/classification/*enzymology ; Protein Folding ; Protein Structure, Tertiary ; Ribosomes/*enzymology ; Sequence Alignment

2018-03-06

BMJ Publishing

2044-6055

Medicine

Open access, Epidemiology, Epidemiology

1089-7550

AIP Digital Archive

Physics

Spin-dependent tunnel junctions, Co/Al2O3/Co (CoFe)/NiFe, were fabricated to investigate the effect of the additional Co (CoFe) interlayer on tunneling magnetoresistance. The quality of the junction was examined with a cross-sectional image generated by high-resolution transmission electron microscopy, and an electron energy loss spectra map. For junctions with a Co (CoFe) interlayer in the top electrode thinner than 0.8 nm (1.0 nm), the tunneling magnetoresistance ratio increases with interlayer thickness. For junctions with a 0.8–2.0 nm Co (1.0–2.0 nm CoFe) interlayer in the top electrode, the tunneling magnetoresistance ratio reaches the maximum value of 2.16 (4.45) times that without any Co (CoFe) interlayer in the top electrode. The increase in the tunneling magnetoresistance ratio may be attributed to the increased effective ferromagnetic electrode polarization and the various spin-flip scattering factors. © 2001 American Institute of Physics.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

The trilayers 10 nm NiO(AF)/X Cu/10 nm NiFe(FM) were prepared for the study on the temperature effect in interlayer exchange bias coupling. The characteristic behavior of the interlayer exchange bias coupling as a function the spacer thickness was shown to strongly depend on the temperature. A monotonic decrease of the exchange bias field with increasing Cu spacer layer was observed at low temperature around 20 K. At higher temperatures (about 145 K), a clear oscillatory evolution of the exchange bias field with the Cu thickness was found even without background subtraction. The temperature-dependent feature of the interlayer exchange bias coupling was also found to vary significantly with different Cu thickness. © 2001 American Institute of Physics.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

The optical absorption of synthetic ReS2 and ReSe2 single crystals is reported over a temperature range from 25 to 300 K. Analysis reveals that the absorption edges of ReS2 and ReSe2 are indirect allowed transitions. The indirect band gaps at various temperatures are determined and their temperature dependence is analyzed by the Varshni equation [Physica 34, 149 (1967)] and an empirical expression proposed by O'Donnel and Chen [Appl. Phys. Lett. 58, 2924 (1991)]. The parameters that describe the temperature dependence of energy gaps of these two materials are evaluated and discussed. © 1997 American Institute of Physics.

Electronic Resource

0003-2697

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Electronic Resource

0014-4827

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Medicine

Electronic Resource

0021-9673

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Electronic Resource

0020-7462

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Physics

Electronic Resource

0027-5107

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Medicine

Electronic Resource

0027-5107

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Medicine

Electronic Resource

0022-4073

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Physics

Electronic Resource

0006-291X

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Physics

Electronic Resource

0003-2670

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Electronic Resource

1432-0584

Temperature ; Platelet aggregation test ; Packed cell ; Platelet number ; Platelet size

Springer Online Journal Archives 1860-2000

Medicine

Abstract The influences of time of storage of plateletrich plasma (PRP), temperature of storage of PRP, platelet number in PRP, mean platelet volume in whole blood, sex, age, hemoglobin concentration, and different forms of PRP storage on platelet aggregation (PAG) tests, performed with epinephrine, collagen, arachidonate, and ristocetin by a four-channel aggregation profiler (Platelet Aggregation Profiler, Model PAP-4, Bio/Data Corporation, Hatboro, PA 19040, U.S.A.), were evaluated in four groups of subjects (52 men, 22 women, age range 20–85 years, hemoglobin concentration range 8.4–16.8 g/dl). The PRP was stored with or without packed cells, at room temperature or at 4° C, for 0–6 h. The ideal platelet number of PRP for performing the PAG test fell between 150 and 500 × 109/l. If the number was less than 150 × 109/l, the result of PAG should be meaningless. No significant change was noted for up to 6 h when the PRP was stored either at room temperature or at 4° C. Hemoglobin concentration and mean platelet volume did not affect the PAG. However, there was significant but weak correlation (p = 0.0125,r = 0.3696) between age and PAG when using arachidonic acid as the agonist. Men had significantly increased PAG when collagen and ristocetin were used as the agonists. The PRP was stored best at room temperature, without packed cells. In conclusion, to obtain the best result from a PAG test, the PRP should be kept without packed cells at room temperature for no longer than 6 h, and the platelet number should fall between 150 and 500 × 109/l.

Electronic Resource

0165-1161

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Medicine

Electronic Resource

1432-0584

Key words Temperature ; Platelet aggregation test ; Packed cell ; Platelet number ; Platelet size

Springer Online Journal Archives 1860-2000

Medicine

Abstract  The influences of time of storage of platelet-rich plasma (PRP), temperature of storage of PRP, platelet number in PRP, mean platelet volume in whole blood, sex, age, hemoglobin concentration, and different forms of PRP storage on platelet aggregation (PAG) tests, performed with epinephrine, collagen, arachidonate, and ristocetin by a four-channel aggregation profiler (Platelet Aggregation Profiler, Model PAP-4, Bio/Data Corporation, Hatboro, PA 19040, U.S.A.), were evaluated in four groups of subjects (52 men, 22 women, age range 20–85 years, hemoglobin concentration range 8.4–16.8 g/dl). The PRP was stored with or without packed cells, at room temperature or at 4°  C, for 0–6 h. The ideal platelet number of PRP for performing the PAG test fell between 150 and 500×109/l. If the number was less than 150×109/l, the result of PAG should be meaningless. No significant change was noted for up to 6 h when the PRP was stored either at room temperature or at 4°  C. Hemoglobin concentration and mean platelet volume did not affect the PAG. However, there was significant but weak correlation (p = 0.0125, r = 0.3696) between age and PAG when using arachidonic acid as the agonist. Men had significantly increased PAG when collagen and ristocetin were used as the agonists. The PRP was stored best at room temperature, without packed cells. In conclusion, to obtain the best result from a PAG test, the PRP should be kept without packed cells at room temperature for no longer than 6 h, and the platelet number should fall between 150 and 500×109/l.

Electronic Resource

1432-0584

Aplastic anemia ; MIP-1α ; TNF-α ; TGF-β2 ; IFN-γ

Springer Online Journal Archives 1860-2000

Medicine

Abstract The aim of this study was to measure the level of cytokines produced by peripheral blood mononuclear cells (PBMNC) in patients with aplastic anemia (AA) and to determine their effect on the clonal growth of normal bone marrow (BM) cells. Twenty-one patients with AA and 11 normal controls were enrolled in this study. Medium conditioned by PBMNC of AA patients in the presence of lipopolysaccharide (LPS) was found to be suppressive to the colony growth of normal BM cells. Thus, we further determined the presence in the PBMNC-conditioned medium (CM) of both inhibitory cytokines: macrophage inflammatory protein-1α (MIP-1α), tumor necrosis factor-α (TNF-α), transforming growth factor-β2 (TGF-β2), and interferon-γ (IFN-γ), and stimulatory cytokines: interleukin-3 (IL-3) and stem cell factor (SCF). Spontaneous production of MlP-1α was higher in the AA patients than the normal controls (1887±174 pg/ml vs 1643±93 pg/ml), but the difference was not significant. After LPS stimulation, the production of MIP-1α was markedly increased in the AA patients, and its level was significantly higher than that of the normal controls (2360±149 pg/ml vs 1517±92 pg/ml, p=0.0022). The level of TNFα was also higher in the AA patients. However, IFN-γ, TGF-β2, SCF, and IL-3 were not detectable in the PBMNC-CM of either AA patients or normals. The myelopoietic suppressing effect of AA-PBMNC-CM from each AA patient was significantly blocked by pretreatment with anti-TNF-α, resulting in a colony-forming enhancement of 174%±12%. A similar effect was noted in six of 11 AA patients by pretreatment with anti-MIP-1α. We conclude that TNFα and MIP-1α can be overproduced by the PBMNC of some AA patients, which may play a role in the progression of AA.

Electronic Resource