Search Results - (Author, Cooperation:C. Fabbri)

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  1. 1
    M. Roffet-Salque ; M. Regert ; R. P. Evershed ; A. K. Outram ; L. J. Cramp ; O. Decavallas ; J. Dunne ; P. Gerbault ; S. Mileto ; S. Mirabaud ; M. Paakkonen ; J. Smyth ; L. Soberl ; H. L. Whelton ; A. Alday-Ruiz ; H. Asplund ; M. Bartkowiak ; E. Bayer-Niemeier ; L. Belhouchet ; F. Bernardini ; M. Budja ; G. Cooney ; M. Cubas ; E. M. Danaher ; M. Diniz ; L. Domboroczki ; C. Fabbri ; J. E. Gonzalez-Urquijo ; J. Guilaine ; S. Hachi ; B. N. Hartwell ; D. Hofmann ; I. Hohle ; J. J. Ibanez ; N. Karul ; F. Kherbouche ; J. Kiely ; K. Kotsakis ; F. Lueth ; J. P. Mallory ; C. Manen ; A. Marciniak ; B. Maurice-Chabard ; M. A. Mc Gonigle ; S. Mulazzani ; M. Ozdogan ; O. S. Peric ; S. R. Peric ; J. Petrasch ; A. M. Petrequin ; P. Petrequin ; U. Poensgen ; C. J. Pollard ; F. Poplin ; G. Radi ; P. Stadler ; H. Stauble ; N. Tasic ; D. Urem-Kotsou ; J. B. Vukovic ; F. Walsh ; A. Whittle ; S. Wolfram ; L. Zapata-Pena ; J. Zoughlami
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-11-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Africa, Northern ; Animals ; Archaeology ; Beekeeping/*history ; *Bees ; Ceramics/chemistry/history ; Europe ; Farmers/history ; Geographic Mapping ; History, Ancient ; Lipids/analysis/chemistry ; Middle East ; Spatio-Temporal Analysis ; Waxes/*analysis/chemistry/*history
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-06-09
    Publisher:
    The American Society for Pharmacology and Experimental Therapeutics (ASPET)
    Print ISSN:
    0031-6997
    Electronic ISSN:
    1521-0081
    Topics:
    Chemistry and Pharmacology
    Medicine
    Published by:
    http://www.aspet.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Miadonna, A. ; Tedeschi, A. ; Leggieri, E. ; Fabbri, C. ; Lorini, M. ; Froldi, M. ; Zanussi, C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1987
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The effect of the new calcium antagonist nitrendipine on in vitro basophil activation was evaluated in 10 subjects. The histamine release induced by calcium ionophore A23187, f-met peptide and anti-IgE was inhibited, in a dose-dependent fashion, by nitrendipine in the concentration range of 1–100 μM. The activity of this calcium antagonist seems complex and related to an interference with calcium at multiple sites. At concentrations higher than 200 μM, nitrendipine causes histamine release from basophil leukocytes. This histamine secretion is likely to be due to a cytotoxic effect, since it is associated with an increase in LDH levels in the cell supernatant.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1398-9995.1987.tb02213.x

    Articles: DFG German National Licenses
  4. 4
    Fiorucci, S. ; Santucci, L. ; Gerli, R. ; Brunori, P. M. ; Federici, B. ; Ugolini, B. ; Fabbri, C. ; Morelli, A.

    Oxford UK : Blackwell Science Ltd.
    Published 1997
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Margination of circulating neutrophils (PMN) into the gastric microcirculation is an early and critical event in the pathogenesis of non-steroidal antinflammatory drug (NSAID)-induced gastropathy. This effect is mediated through the upregulation of β2 integrins on the PMN surface.〈section xml:id="abs1-2"〉〈title type="main"〉Aims:To investigate whether indomethacin modulates: (1) Mac-1 expression; (2) Ca2+ mobilization ([Ca2+]i), protein kinase C and nitric oxide accumulation; and (3) mitogen-associated protein kinase phosphorylation in human PMN.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:Human PMN were isolated by centrifugation through a double Ficoll gradient. [Ca2+]i was measured in PMN loaded with fura-2 and Mac-1 expression by flow cytometry.〈section xml:id="abs1-4"〉〈title type="main"〉Results:Indomethacin caused a concentration- and time-dependent upregulation of CD11b and CD18 expression and PMN adhesion to endothelial cells. Maximal upregulation of Mac-1 expression (40–50%) occurred after a 30-min incubation with 0.1 mM indomethacin. The effect was prevented by removing the Ca2+. Ionomycin and thapsigargin caused a 7–10-fold increase in [Ca2+]i and a 2–4-fold increase in Mac-1 expression. Indomethacin induced a concentration-dependent phosphorylation of a 41-kDa mitogen-associated protein kinase. Tyrosine kinase inhibitors prevented the effect of indomethacin on Mac-1 expression and Ca2+ mobilization. Indomethacin and ionomycin increased superoxide generation, myeloperoxidase secretion and PMN adherence to endothelial cells and stimulated nitric oxide production. Indomethacin-induced Mac-1 upregulation was prevented by a nitric oxide synthase inhibitor.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:Indomethacin-induced upregulation of Mac-1 is mediated by changes in [Ca2+]i and nitric oxide. Phosphorylation of the 41-kDa mitogen-associated protein isoform is a previously unreported target of NSAID action. These effects might help to explain the ability of indomethacin to cause gastric neutrophil margination.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2036.1997.00190.x

    Articles: DFG German National Licenses
  5. 5
    Antonelli, A. ; Fabbri, C. ; Lercker, G.
    Springer
    Published 1996
    Staff View
    ISSN:
    1612-1112
    Keywords:
    Gas Chromatography ; Resveratrol ; Silylation ; Bis (trimethylsilyl) trifluoroacetamide
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    Summary Resveratrol, a wine stilbene phytoalexin with some pharmacological properties, was extracted from red wines by MeOH elution of a Sephadex LH-20 column, used for its purification. The column extract was dried and silylated by different methods to optimize resveratrol derivatization. The resveratrol analysis was by gas chromatography and gas cromatography-mass spectrometry allowing determination of its two isomers.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02272141

    Articles: DFG German National Licenses