Search Results - (Author, Cooperation:C. E. Nelson)
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1C. E. Nelson ; C. H. Hakim ; D. G. Ousterout ; P. I. Thakore ; E. A. Moreb ; R. M. Castellanos Rivera ; S. Madhavan ; X. Pan ; F. A. Ran ; W. X. Yan ; A. Asokan ; F. Zhang ; D. Duan ; C. A. Gersbach
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-01-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *CRISPR-Cas Systems ; Clustered Regularly Interspaced Short Palindromic Repeats ; Dependovirus ; Disease Models, Animal ; Dystrophin/*genetics ; Exons/*genetics ; Genetic Therapy/*methods ; Male ; Mice ; Mice, Inbred mdx ; Muscle, Skeletal/*metabolism ; Muscular Dystrophy, Duchenne/genetics/*therapy ; Sequence DeletionPublished by: -
2GOESCHL, J. D. ; MAGNUSON, C. E. ; FARES, Y. ; JAEGER, C. H. ; NELSON, C. E. ; STRAIN, B. R.
Oxford, UK : Blackwell Publishing Ltd
Published 1984Staff ViewISSN: 1365-3040Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Abstract Steady-state labelling with 11CO2 was used to observe the blocking of phloem transport, induced by chilling short regions of stems or petioles of velvetleaf (Abutilon theophrasti Medic.) or cotton (Gossipium hirsutum L.). The abruptness of these blockages was evidenced by sharp decreases in 11C activity below, and increases above a 2 to 3 cm region cooled from 28°C to 18 or 13°C for periods as short as 2 min. Abrupt unblocking of transport in velvetleaf occurred a few minutes after rewarming, as evidenced by a sharp rise and and overshoot in 11C activity. Recovery of transport in cotton was more prolonged and was marked by occasional spontaneous blocking and unblocking of transport at various points along the petiole or stem, not necessarily in the cooled region. Similar spontaneous events were often observed in undisturbed cotton plants, but only rarely in velvetleaf.Type of Medium: Electronic ResourceURL: -
3Staff View
ISSN: 0196-3570Topics: Linguistics and Literary StudiesNotes: Not in the ReviewsURL: -
4Staff View
ISSN: 0196-3570Topics: Linguistics and Literary StudiesNotes: Not in the ReviewsURL: -
5Staff View
ISSN: 0196-3570Topics: Linguistics and Literary StudiesNotes: Not in the ReviewsURL: -
6Staff View
ISSN: 0196-3570Topics: Linguistics and Literary StudiesNotes: Not in the ReviewsURL: -
7Staff View
ISSN: 1434-0879Keywords: Male sterility ; Vas deferens ; reanastomosis ; experimental model ; dogsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary The conditions for healing of the vas deferens have been studied in the dog. A length of twisted steel wire or nylon 4/0 inserted into the lumen of the duct gave rise to considerable histological changes after ten days. Obstruction developed in four out of ten anastomoses in which such suture material was used as a splint. A method of nonsplinted anastomosis is described. Nine out of ten anastomoses using this technique exhibited patency with a very limited histological reaction after the procedure.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0026-7937Topics: Linguistics and Literary StudiesNotes: NOTESURL: -
9Staff View
ISSN: 1420-8903Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1420-8903Keywords: 10E25 ; 10E05 ; 10E20Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
11Magnuson, C. E. ; Fares, Y. ; Goeschl, J. D. ; Nelson, C. E. ; Strain, B. R. ; Jaeger, C. H. ; Bilpuch, E. G.
Springer
Published 1982Staff ViewISSN: 1432-2099Source: Springer Online Journal Archives 1860-2000Topics: BiologyPhysicsNotes: Summary An integrated approach to study the effects of environmental factors on plants is described. The central theme of the system is the use of CO2 labelled with11C supplied continuously to the plant and following the emitted radiation in vivo in the leaf, the phloem and the various sinks. The system consists of six components and with minor changes can be used for other tracers such as13N for nitrogen fixation studies. Because of the short half life of the isotope, several experiments can be carried out on the same plant under the same environmental conditions without disturbing the plant. A host of ecologically, agriculturally and genetically important questions can be answered using this technique.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1432-1866Source: Springer Online Journal Archives 1860-2000Topics: GeosciencesNotes: Abstract Gold mineralization in the Pueblo Viejo district, Dominican Republic, is spatially and temporally related to a series of Early Cretaceous volcanic domes. Separate but overlapping hydrothermal cells, centered on the domes, together deposited more than 40 million oz. of gold, 240 million oz. of silver, 3 million tonnes of zinc, and 0.4 million tonnes of copper. Two principal deposits (Moore and Monte Negro) and a number of smaller deposits (Cumba, Mejita, Upper Mejita, Banco V, Arroyo Hondo I and II) have contributed ore since mining commenced in 1975. New geologic mapping has identified a series of previously unrecognized volcanic domes that vary from andesite to dacite in composition. A dacite porphyry dome intrudes epiclastic sediments in the Moore deposit and is surrounded by a baked contact metamorphic aureole. Crumble breccias of mixed epiclastic and pyroclastic origin mantle andesite domes in the Monte Negro, Cumba, and Mejita deposits. Epiclastic volcanic sediments surrounding each of the domes reflect the composition of the local source rock. Andesite domes of the Monte Negro deposit are surrounded by andesitic volcaniclastic sediments. Epiclastic sediments surrounding a dacite porphyry dome in the Moore deposit contain detrital quartz eyes and debris flows of dacite porphyry. A series of at least seven volcanic centers interfinger, overlap, and are interbedded with locally derived epiclastic sediments. Field relations indicate that volcanic dome emplacement, epiclastic sediment accumulation, hydrothermal alteration, and gold mineralization were coeval events. Domes were emplaced in a shallow subaqueous environment on the flanks of an emergent volcanic edifice. Hydrothermal cells responsible for gold mineralization are controlled by high-angle faults. These same faults influenced the emplacement of volcanic domes, an essential step in the development of gold ore in the Pueblo Viejo district.Type of Medium: Electronic ResourceURL: