Search Results - (Author, Cooperation:C. D. Allis)
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1B. W. Carey ; L. W. Finley ; J. R. Cross ; C. D. Allis ; C. B. Thompson
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-12-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Differentiation/drug effects ; Cell Line ; Cell Membrane Permeability ; Cell Proliferation ; Chromatin/drug effects ; DNA Methylation/drug effects ; Embryonic Stem Cells/*cytology/drug effects/metabolism ; Epigenesis, Genetic/drug effects/genetics ; Glucose/metabolism ; Glutamic Acid/metabolism ; Histones/metabolism ; Intracellular Space/*metabolism ; Ketoglutaric Acids/*metabolism/pharmacology ; Methylation ; Mice ; Pluripotent Stem Cells/*cytology/drug effects/metabolism ; Succinic Acid/metabolism/pharmacology ; Transcription, Genetic/drug effectsPublished by: -
2S. J. Elsasser ; C. D. Allis ; P. W. Lewis
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-03-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/*genetics/metabolism ; Chromatin/metabolism ; Chromatin Assembly and Disassembly/genetics ; DNA Helicases/*genetics/metabolism ; *Epigenesis, Genetic ; *Genes, Tumor Suppressor ; Histones/metabolism ; Humans ; Mutation ; Neuroendocrine Tumors/*genetics/metabolism ; Nuclear Proteins/*genetics/metabolism ; Nucleosomes/metabolism ; Pancreatic Neoplasms/*genetics/metabolism ; Proto-Oncogene Proteins/*genetics/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolismPublished by: -
3K. Funato ; T. Major ; P. W. Lewis ; C. D. Allis ; V. Tabar
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-12-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antineoplastic Agents/pharmacology ; Brain Stem Neoplasms/*genetics/pathology ; Cell Transformation, Neoplastic/*genetics/pathology ; Child ; Drug Screening Assays, Antitumor ; Embryonic Stem Cells/*metabolism/pathology ; Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic ; Genome-Wide Association Study ; Glioma/*genetics/pathology ; Histones/*genetics ; Humans ; Mice ; *Models, Genetic ; Neural Stem Cells/*metabolism/pathology ; Proto-Oncogene Proteins/antagonists & inhibitors ; Tumor Suppressor Protein p53/geneticsPublished by: -
4P. W. Lewis ; M. M. Muller ; M. S. Koletsky ; F. Cordero ; S. Lin ; L. A. Banaszynski ; B. A. Garcia ; T. W. Muir ; O. J. Becher ; C. D. Allis
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-03-30Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Substitution ; Animals ; Brain Neoplasms/*enzymology/*genetics ; Child ; *Epigenesis, Genetic ; Glioblastoma/*enzymology/*genetics ; HEK293 Cells ; Histones/*genetics/metabolism ; Humans ; Lysine/genetics ; Methionine/genetics ; Methylation ; Mice ; Mutation, Missense ; Polycomb Repressive Complex 2/*antagonists & inhibitors/metabolism ; TransgenesPublished by: -
5C. Lu ; S. U. Jain ; D. Hoelper ; D. Bechet ; R. C. Molden ; L. Ran ; D. Murphy ; S. Venneti ; M. Hameed ; B. R. Pawel ; J. S. Wunder ; B. C. Dickson ; S. M. Lundgren ; K. S. Jani ; N. De Jay ; S. Papillon-Cavanagh ; I. L. Andrulis ; S. L. Sawyer ; D. Grynspan ; R. E. Turcotte ; J. Nadaf ; S. Fahiminiyah ; T. W. Muir ; J. Majewski ; C. B. Thompson ; P. Chi ; B. A. Garcia ; C. D. Allis ; N. Jabado ; P. W. Lewis
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-05-14Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
6S. J. Elsasser ; K. M. Noh ; N. Diaz ; C. D. Allis ; L. A. Banaszynski
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-05-06Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Carrier Proteins/metabolism ; Cell Line ; DNA Helicases/metabolism ; Embryonic Stem Cells/*virology ; Endogenous Retroviruses/*genetics ; *Gene Silencing ; Genomic Instability ; Heterochromatin/genetics/metabolism ; Histones/chemistry/*metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Methylation ; Mice ; Nuclear Proteins/metabolismPublished by: -
7S. J. Elsasser ; H. Huang ; P. W. Lewis ; J. W. Chin ; C. D. Allis ; D. J. Patel
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-10-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/chemistry/metabolism ; Amino Acid Sequence ; Binding, Competitive ; Cell Cycle Proteins/genetics/metabolism ; Crystallography, X-Ray ; DNA/chemistry/*metabolism ; Histone Chaperones/chemistry/metabolism ; Histones/*chemistry/*metabolism ; Humans ; Models, Molecular ; Molecular Sequence Data ; Nuclear Proteins/chemistry/metabolism ; Nucleosomes/chemistry/metabolism ; Protein Conformation ; Protein Multimerization ; Substrate Specificity ; Water/chemistry/metabolismPublished by: -
8Staff View
ISSN: 1420-9071Keywords: Key words. Transcription; chromatin; nucleosomes; histones; acetylation; acetyltransferases.Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract. In eukaryotes, DNA is assembled with histones to form nucleosomes, the basic subunit of chromatin structure. The wrapping of DNA around histone octamers to form nucleosomal filaments and further folding of these filaments are necessary to contain eukaryotic genomes within nuclei. However, the dense packing of chromatin in nuclei and the association of DNA with histones restrict the access of proteins involved in gene transcription to DNA. Abundant biochemical data supports a long-standing correlation between histone acetylation and gene activation, suggesting that histone acetylation acts to enhance the access of transcription-associated proteins to DNA. However, despite this correlation, nuclear enzymes responsible for transcription-associated histone acetylation have been identified only recently. Here we review evidence suggesting that histone acetylation represents a major pathway for transcriptional regulation, and discuss possible roles for transcription-associated histone acetyltransferases in this regulation.Type of Medium: Electronic ResourceURL: