Search Results - (Author, Cooperation:C. Borel)
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1A. Letourneau ; F. A. Santoni ; X. Bonilla ; M. R. Sailani ; D. Gonzalez ; J. Kind ; C. Chevalier ; R. Thurman ; R. S. Sandstrom ; Y. Hibaoui ; M. Garieri ; K. Popadin ; E. Falconnet ; M. Gagnebin ; C. Gehrig ; A. Vannier ; M. Guipponi ; L. Farinelli ; D. Robyr ; E. Migliavacca ; C. Borel ; S. Deutsch ; A. Feki ; J. A. Stamatoyannopoulos ; Y. Herault ; B. van Steensel ; R. Guigo ; S. E. Antonarakis
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-04-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cells, Cultured ; Chromatin/chemistry/metabolism ; Chromosomes, Human, Pair 21/genetics ; Chromosomes, Mammalian/genetics ; DNA Replication Timing ; Down Syndrome/*genetics/pathology ; Female ; Fetus/cytology ; Fibroblasts ; Gene Expression Regulation/*genetics ; Genome/*genetics ; Histones/chemistry/metabolism ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Lysine/metabolism ; Male ; Methylation ; Mice ; Transcriptome/*genetics ; Twins, Monozygotic/geneticsPublished by: -
2A. Letourneau ; F. A. Santoni ; X. Bonilla ; M. R. Sailani ; D. Gonzalez ; J. Kind ; C. Chevalier ; R. Thurman ; R. S. Sandstrom ; Y. Hibaoui ; M. Garieri ; K. Popadin ; E. Falconnet ; M. Gagnebin ; C. Gehrig ; A. Vannier ; M. Guipponi ; L. Farinelli ; D. Robyr ; E. Migliavacca ; C. Borel ; S. Deutsch ; A. Feki ; J. A. Stamatoyannopoulos ; Y. Herault ; B. van Steensel ; R. Guigo ; S. E. Antonarakis
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-12-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Shepherd, D. P. ; Hanna, D. C. ; Large, A. C. ; Tropper, A. C. ; Warburton, T. J. ; Borel, C. ; Ferrand, B. ; Pelenc, D. ; Rameix, A. ; Thony, P. ; Auzel, F. ; Meichenin, D.
[S.l.] : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Room temperature 1.64 μm laser operation of Yb:Er:Y3Al5O12 has been achieved using a planar waveguide grown by liquid phase epitaxy. A comparatively low threshold of 17 mW was achieved for this transition indicating low waveguide propagation loss for this material and suggesting good prospects for low threshold 3 μm and upconversion visible lasers based on this system. © 1994 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Souriau, J. C. ; Romero, R. ; Borel, C. ; Wyon, C. ; Li, C. ; Moncorgé, R.
Woodbury, NY : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Continuous-wave (cw) laser operation at room temperature of an Yb3+, Er3+ doped oxyapatite single crystal SrY4(SiO4)3O pumped at 980 nm by an InGaAs diode laser has been achieved around the eye-safe laser wavelength of 1554 nm.Type of Medium: Electronic ResourceURL: -
5Foulon, F. ; Bergonzo, P. ; Borel, C. ; Marshall, R. D. ; Jany, C. ; Besombes, L. ; Brambilla, A.
[S.l.] : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: A major difficulty in characterizing vacuum ultraviolet (VUV) radiation produced by harmonic generation or four-wave sum frequency mixing arises in differentiating between the desired VUV signal and the remaining fundamental pump laser beam. To overcome this problem, visible and near UV blind VUV detectors, made from natural and synthetic diamond, have been developed. Such detectors have been used to characterize coherent VUV pulses (λ=125 nm, pulse duration at full width half maximum (FWHM) τFWHM∼7 ns) generated by resonance-enhanced four-wave sum mixing in mercury vapor. They allow full characterization of the intensity profile of the VUV pulses, without any significant parasitic signal from simultaneous stray light irradiation at λ=313 nm. Detectors were fabricated exhibiting response times of less than 70 ps at FWHM, corresponding to the lowest response time obtainable with a 7 GHz bandwidth single-shot oscilloscope. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Borel, C. ; Frey, A. ; Marion-Poll, A. ; Tardieu, F. ; Simonneau, T.
Oxford, UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-3040Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: The consequences of manipulating abscisic acid (ABA) biosynthesis rates on stomatal response to drought were analysed in wild-type, a full-deficient mutant and four under-producing transgenic lines of N. plumbaginifolia. The roles of ABA, xylem sap pH and leaf water potential were investigated under four experimental conditions: feeding detached leaves with varying ABA concentration; injecting exogenous ABA into well-watered plants; and withholding irrigation on pot-grown plants, either intact or grafted onto tobacco. Changes in ABA synthesis abilities among lines did not affect stomatal sensitivity to ABA concentration in the leaf xylem sap ([ABA]xyl), as evidenced with exogenous ABA supplies and natural increases of [ABA]xyl in grafted plants subjected to drought. The ABA-deficient mutant, which is uncultivable under normal evaporative demand, was grafted onto tobacco stock and then presented the same stomatal response to [ABA]xyl as wild-type and other lines. This reinforces the dominant role of ABA in controlling stomatal response to drought in N. plumbaginifolia whereas roles of leaf water potential and xylem sap pH were excluded under all studied conditions. However, when plants were submitted to soil drying onto their own roots, stomatal response to [ABA]xyl slightly differed among lines. It is suggested, consistently with all the results, that an additional root signal of soil drying modulates stomatal response to [ABA]xyl.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0925-3467Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0031-9422Keywords: Leguminosae ; Swartzia simplex ; molluscicidal activity. ; schistosomiasis ; triterpene saponinsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1569-8041Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
15Kurtz, J. E. ; Deplanque, G. ; Borel, C. ; Mathelin, C. ; Prévost, G. ; Poulin, G. ; Barats, J. C. ; Bergerat, J. P. ; Chapelle-Marcillac, I. ; Bardonnet, M. ; Dufour, P.
Springer
Published 2000Staff ViewISSN: 1569-8041Keywords: breast cancer ; cyclophosphamide ; elderly ; idarubicin ; oral chemotherapySource: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1432-0649Keywords: PACS: 42.55 R; 42.70; 78Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract. Nd-doped CaWO4 (CWO) and NaGd(WO4)2 (NGWO) single crystals with good optical quality have been grown by the Czochralski technique. The neodymium distribution coefficient in these matrices is about 0.4 for CWO and close to unity for NGWO. Polarized absorption and emission spectra have been recorded at room temperature and used to calculate the absorption and stimulated emission cross-sections. 1 and 2% Nd : CWO and 1% Nd:NGWO laser rods have been tested in a cavity longitudinaly pumped by an 1 W AIGaAs laser diode and compared to Nd : YAG and Nd : YVO4 rods in the same conditions. The 2% Nd : CWO rod exhibits the best performance with slope efficiencies of 64%, higher than in the case of YAG and equal to the YVO4 samples. The dependence of the laser output power versus the diode temperature has been measured for all these materials. The laser output of Nd : CWO was found to be nearly as stable as for Nd : YVO4 and much more stable than in the case of Nd : YAG. A CWO microchip has also been tested for the first time to our knowledge.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1432-0649Keywords: 42.55 R ; 42.70 ; 78Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract Nd-doped CaWO4 (CWO) and NaGd(WO4)2 (NGWO) single crystals with good optical quality have been grown by the Czochralski technique. The neodymium distribution coefficient in these matrices is about 0.4 for CWO and close to unity for NGWO. Polarized absorption and emission spectra have been recorded at room temperature and used to calculate the absorption and stimulated emission cross-sections. 1 and 2% Nd : CWO and 1 % Nd:NGWO laser rods have been tested in a cavity longitudinaly pumped by an 1 W AIGaAs laser diode and compared to Nd : YAG and Nd:YVO4 rods in the same conditions. The 2% Nd: CWO rod exhibits the best performance with slope efficiencies of 64%, higher than in the case of YAG and equal to the YVO4 samples. The dependence of the laser output power versus the diode temperature has been measured for all these materials. The laser output of Nd: CWO was found to be nearly as stable as for Nd : YVO4 and much more stable than in the case of Nd : YAG. A CWO microchip has also been tested for the first time to our knowledge.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0030-4018Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Khayat, D. ; Borel, C. ; Azab, M. ; Paraisot, D. ; Malaurie, E. ; Bouloux, C. ; Weil, M.
Springer
Published 1992Staff ViewISSN: 1432-0843Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Datelliptium chloride, hydrochloride (SR 95 156B, NSC 626718X, DHE) was studied in a phase I trial of escalating doses given on a single 24-h continuous intravenous infusion schedule. Doses were escalated from 40 to 500 mg/m2 in 19 patients who received a total of 24 courses. Courses were repeated after a minimal interval of 3 weeks. Local venous toxicity occurred at low doses (≤100 mg/m2) and was circumvented by the use of a central venous access for higher doses. Other clinical adverse events occurred (≥330 mg/m2), including moderate nausea and vomiting, mild diarrhea, dry mouth, neuropsychiatric manifestations, and fatigue. All of these side effects were reversible and none was dose-limiting. The dose-limiting toxicity was related to hepatic laboratory-test abnormalities in the form of reversible elevations of levels of serum bilirubin and liver enzymes at doses of ≥330 mg/m2. The maximum tolerated dose for this schedule is 500 mg/m2. Hematologic toxicity was minimal and non-dose-limiting. Neither drug-related deaths nor objective complete or partial responses were observed. However, a minor response and a long-term disease stabilization were obtained.Type of Medium: Electronic ResourceURL: