Search Results - (Author, Cooperation:C. A. Sullivan)
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1I. Iossifov ; B. J. O'Roak ; S. J. Sanders ; M. Ronemus ; N. Krumm ; D. Levy ; H. A. Stessman ; K. T. Witherspoon ; L. Vives ; K. E. Patterson ; J. D. Smith ; B. Paeper ; D. A. Nickerson ; J. Dea ; S. Dong ; L. E. Gonzalez ; J. D. Mandell ; S. M. Mane ; M. T. Murtha ; C. A. Sullivan ; M. F. Walker ; Z. Waqar ; L. Wei ; A. J. Willsey ; B. Yamrom ; Y. H. Lee ; E. Grabowska ; E. Dalkic ; Z. Wang ; S. Marks ; P. Andrews ; A. Leotta ; J. Kendall ; I. Hakker ; J. Rosenbaum ; B. Ma ; L. Rodgers ; J. Troge ; G. Narzisi ; S. Yoon ; M. C. Schatz ; K. Ye ; W. R. McCombie ; J. Shendure ; E. E. Eichler ; M. W. State ; M. Wigler
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-11-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Child ; Child Development Disorders, Pervasive/*genetics ; Cluster Analysis ; Exome/genetics ; Female ; Genes ; Genetic Predisposition to Disease/*genetics ; Humans ; Intelligence Tests ; Male ; Mutation/*genetics ; Open Reading Frames/*genetics ; Reproducibility of ResultsPublished by: -
2Pawley, C. J. ; Bodner, S. E. ; Dahlburg, J. P. ; Obenschain, S. P. ; Schmitt, A. J. ; Sethian, J. D. ; Sullivan, C. A.
[S.l.] : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: The uniform and smooth focal profile of the Nike KrF laser [S. Obenschain et al., Phys. Plasmas 3, 2098 (1996)] was used to ablatively accelerate 40 μm thick polystyrene planar targets with pulse shaping to minimize shock heating of the compressed material. The foils had imposed small-amplitude sinusoidal wave perturbations of 60, 30, 20, and 12.5 μm wavelength. The shortest wavelength is near the ablative stabilization cutoff for Rayleigh–Taylor growth. Modification of the saturated wave structure due to random laser imprint was observed. Excellent agreement was found between the two-dimensional simulations and experimental data for most cases where the laser imprint was not dominant. © 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
3Pawley, C. J. ; Gerber, K. ; Lehmberg, R. H. ; McLean, E. A. ; Mostovych, A. N. ; Obenschain, S. P. ; Sethian, J. D. ; Serlin, V. ; Stamper, J. A. ; Sullivan, C. A. ; Bodner, S. E. ; Colombant, D. ; Dahlburg, J. P. ; Schmitt, A. J.
[S.l.] : American Institute of Physics (AIP)
Published 1997Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Nike is a 56 beam Krypton Fluoride (KrF) laser system using Induced Spatial Incoherence (ISI) beam smoothing with a measured focal nonuniformity 〈ΔI/I〉 of 1% rms in a single beam [S. Obenschain et al., Phys. Plasmas 3, 1996 (2098)]. When 37 of these beams are overlapped on the target, we estimate that the beam nonuniformity is reduced by 37, to (ΔI/I)≅0.15% (excluding short-wavelength beam-to-beam interference). The extraordinary uniformity of the laser drive, along with a newly developed x-ray framing diagnostic, has provided a unique facility for the accurate measurements of Rayleigh–Taylor amplified laser-imprinted mass perturbations under conditions relevant to direct-drive laser fusion. Data from targets with smooth surfaces as well as those with impressed sine wave perturbations agree with our two-dimensional (2-D) radiation hydrodynamics code that includes the time-dependent ISI beam modulations. A 2-D simulation of a target with a 100 Å rms randomly rough surface finish driven by a completely uniform beam gives final perturbation amplitudes similar to the experimental data for the smoothest laser profile. These results are promising for direct-drive laser fusion.Type of Medium: Electronic ResourceURL: -
4Obenschain, S. P. ; Bodner, S. E. ; Colombant, D. ; Gerber, K. ; Lehmberg, R. H. ; McLean, E. A. ; Mostovych, A. N. ; Pronko, M. S. ; Pawley, C. J. ; Schmitt, A. J. ; Sethian, J. D. ; Serlin, V. ; Stamper, J. A. ; Sullivan, C. A. ; Dahlburg, J. P. ; Gardner, J. H. ; Chan, Y. ; Deniz, A. V. ; Hardgrove, J. ; Lehecka, T. ; Klapisch, M.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Krypton-fluoride (KrF) lasers are of interest to laser fusion because they have both the large bandwidth capability ((approximately-greater-than)THz) desired for rapid beam smoothing and the short laser wavelength (1/4 μm) needed for good laser–target coupling. Nike is a recently completed 56-beam KrF laser and target facility at the Naval Research Laboratory. Because of its bandwidth of 1 THz FWHM (full width at half-maximum), Nike produces more uniform focal distributions than any other high-energy ultraviolet laser. Nike was designed to study the hydrodynamic instability of ablatively accelerated planar targets. First results show that Nike has spatially uniform ablation pressures (Δp/p〈2%). Targets have been accelerated for distances sufficient to study hydrodynamic instability while maintaining good planarity. In this review we present the performance of the Nike laser in producing uniform illumination, and its performance in correspondingly uniform acceleration of targets. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
5Sethian, J. D. ; Obenschain, S. P. ; Gerber, K. A. ; Pawley, C. J. ; Serlin, V. ; Sullivan, C. A.
[S.l.] : American Institute of Physics (AIP)
Published 1997Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: Nike is a recently completed multi-kilojoule krypton fluoride (KrF) laser that has been built to study the physics of direct drive inertial confinement fusion. This paper describes in detail both the pulsed power and optical performance of the largest amplifier in the Nike laser, the 60 cm amplifier. This is a double pass, double sided, electron beam-pumped system that amplifies the laser beam from an input of 50 J to an output of up to 5 kJ. It has an optical aperture of 60 cm × 60 cm and a gain length of 200 cm. The two electron beams are 60 cm high × 200 cm wide, have a voltage of 640 kV, a current of 540 kA, and a flat top power pulse duration of 250 ns. A 2 kG magnetic field is used to guide the beams and prevent self-pinching. Each electron beam is produced by its own Marx/pulse forming line system. The amplifier has been fully integrated into the Nike system and is used on a daily basis for laser-target experiments. © 1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Sullivan, C. A. ; Destler, W. W. ; Rodgers, J. ; Segalov, Z.
[S.l.] : American Institute of Physics (AIP)
Published 1988Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The propagation of high-power (10–200 kW/cm2 ) short-burst (3–30 ns) microwave pulses in the atmosphere has been studied experimentally. Microwave power from a large orbit gyrotron operating at 9.6 GHz is focused by a large-diameter parabolic reflector into a test cell. The ambient pressure in the test cell was varied over a wide range and the microwave power density necessary for atmospheric breakdown has been determined as a function of ambient pressure and pulse duration. Measurements of the microwave pulse duration before and after breakdown have been obtained to determine the extent to which microwave energy is absorbed or reflected by the breakdown plasma. Results are compared with available theory and previously reported experiments.Type of Medium: Electronic ResourceURL: -
7Mulbrandon, M. J. ; Chen, J. ; Palmadesso, P. J. ; Sullivan, C. A. ; Ali, A. W.
New York, NY : American Institute of Physics (AIP)
Published 1989Staff ViewISSN: 1089-7666Source: AIP Digital ArchiveTopics: PhysicsNotes: A theoretical formulation that provides a basis for generating approximate solutions of the Boltzmann equation for the study of high-powered microwave pulses interacting with a background atmosphere is given. A numerical scheme is implemented using realistic cross sections for electron–nitrogen collisions, including excitation and ionization. It is found that the numerical results agree well with previous experimental and theoretical values when α is less than about 0.1 kV/cm Torr, where α is the effective electric field divided by the pressure (α=Ee/P). Results are presented providing a simple fit for the time averaged momentum transfer rate and the ionization rate as a function of the microwave electric field E, wavelength λ, and gas pressure P, for 0.1≤α≤1.0 kV/cm Torr. This fit is compared with recent experimental data for breakdown times.Type of Medium: Electronic ResourceURL: