Search Results - (Author, Cooperation:B. Walker)
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1Latest Papers from Table of Contents or Articles in PressS. Kulkarni ; R. Savan ; Y. Qi ; X. Gao ; Y. Yuki ; S. E. Bass ; M. P. Martin ; P. Hunt ; S. G. Deeks ; A. Telenti ; F. Pereyra ; D. Goldstein ; S. Wolinsky ; B. Walker ; H. A. Young ; M. Carrington
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-04-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 3' Untranslated Regions/genetics ; Alleles ; Base Sequence ; Cell Line ; *Gene Expression Regulation/genetics/immunology ; Genes, Reporter/genetics ; HIV/*immunology ; HIV Infections/*genetics/*immunology/therapy ; HLA-C Antigens/*genetics ; Humans ; MicroRNAs/*genetics ; Polymorphism, Single Nucleotide/genetics ; Viral LoadPublished by: -
2Latest Papers from Table of Contents or Articles in PressR. Apps ; Y. Qi ; J. M. Carlson ; H. Chen ; X. Gao ; R. Thomas ; Y. Yuki ; G. Q. Del Prete ; P. Goulder ; Z. L. Brumme ; C. J. Brumme ; M. John ; S. Mallal ; G. Nelson ; R. Bosch ; D. Heckerman ; J. L. Stein ; K. A. Soderberg ; M. A. Moody ; T. N. Denny ; X. Zeng ; J. Fang ; A. Moffett ; J. D. Lifson ; J. J. Goedert ; S. Buchbinder ; G. D. Kirk ; J. Fellay ; P. McLaren ; S. G. Deeks ; F. Pereyra ; B. Walker ; N. L. Michael ; A. Weintrob ; S. Wolinsky ; W. Liao ; M. Carrington
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-04-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: African Americans/genetics ; Alleles ; Amino Acid Sequence ; Anti-Retroviral Agents/therapeutic use ; Crohn Disease/genetics/immunology ; *Gene Expression Regulation ; HIV/genetics/*immunology ; HIV Infections/drug therapy/*genetics/*immunology ; HLA-C Antigens/*genetics ; Humans ; Immunodominant Epitopes/genetics ; Molecular Sequence Data ; Mutation ; Peptide Fragments/immunology ; Polymorphism, Single Nucleotide ; T-Lymphocytes, Cytotoxic/*immunology ; Viral Load/geneticsPublished by: -
3Latest Papers from Table of Contents or Articles in PressG. J. Xu ; T. Kula ; Q. Xu ; M. Z. Li ; S. D. Vernon ; T. Ndung'u ; K. Ruxrungtham ; J. Sanchez ; C. Brander ; R. T. Chung ; K. C. O'Connor ; B. Walker ; H. B. Larman ; S. J. Elledge
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-06-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Antibodies, Viral/*blood ; Epitopes, B-Lymphocyte/genetics/*immunology ; High-Throughput Nucleotide Sequencing/methods ; Host-Pathogen Interactions/*immunology ; Humans ; Immune System/*virology ; Immunoprecipitation/methods ; Peptide Library ; Serologic Tests ; Virus Diseases/blood/*diagnosis/immunology ; Viruses/*immunologyPublished by: -
4Latest Papers from Table of Contents or Articles in PressM. Scheffer ; S. Barrett ; S. R. Carpenter ; C. Folke ; A. J. Green ; M. Holmgren ; T. P. Hughes ; S. Kosten ; I. A. van de Leemput ; D. C. Nepstad ; E. H. van Nes ; E. T. Peeters ; B. Walker
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-03-21Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Conservation of Natural Resources ; *Coral Reefs ; *Forests ; *Greenhouse Effect ; *WetlandsPublished by: -
5Latest Papers from Table of Contents or Articles in PressRasche, L., Angtuaco, E. J., Alpe, T. L., Gershner, G. H., McDonald, J. E., Samant, R. S., Kumar, M., Van Hemert, R., Epstein, J., Deshpande, S., Tytarenko, R., Yaccoby, S., Hillengass, J., Thanendrarajan, S., Schinke, C., van Rhee, F., Zangari, M., Walker, B. A., Barlogie, B., Morgan, G. J., Davies, F. E., Weinhold, N.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-07-06Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Multiple Myeloma, Lymphoid Neoplasia, Clinical Trials and ObservationsPublished by: -
6Latest Papers from Table of Contents or Articles in PressRamsuran, V., Naranbhai, V., Horowitz, A., Qi, Y., Martin, M. P., Yuki, Y., Gao, X., Walker-Sperling, V., Del Prete, G. Q., Schneider, D. K., Lifson, J. D., Fellay, J., Deeks, S. G., Martin, J. N., Goedert, J. J., Wolinsky, S. M., Michael, N. L., Kirk, G. D., Buchbinder, S., Haas, D., Ndungu, T., Goulder, P., Parham, P., Walker, B. D., Carlson, J. M., Carrington, M.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-01-05Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Genetics, ImmunologyPublished by: -
7Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-08-10Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Lymphoid NeoplasiaPublished by: -
8Latest Papers from Table of Contents or Articles in PressBaiyegunhi, O., Ndlovu, B., Ogunshola, F., Ismail, N., Walker, B. D., Ndung'u, T., Ndhlovu, Z. M.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-07-18Publisher: The American Society for Microbiology (ASM)Print ISSN: 0022-538XElectronic ISSN: 1098-5514Topics: MedicinePublished by: -
9Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-01-31Publisher: The American Society for Microbiology (ASM)Print ISSN: 0022-538XElectronic ISSN: 1098-5514Topics: MedicinePublished by: -
10Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-11-16Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Free Research ArticlesPublished by: -
11Articles: DFG German National LicensesWALKER, A. R. P. ; WALKER, B. F. ; NCONGWANE, J. ; TSHABALALA, E. N.
Oxford, UK : Blackwell Publishing Ltd
Published 1984Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. Among South African black women in rural areas, breast cancer is rare and remains very uncommon among urban dwellers in Soweto, Johannesburg. Since time of menopause is an influencing factor in breast cancer in white women, mean times were determined in series of 1850 and 1255 black women in rural and urban areas, respectively. Using probit analysis, respective means were 49.5 (SD 4.7) years, and 48.9 (SD 4.2) years. Values thus differ little from those reported for white women. Obviously case control studies are needed to learn of the bearing of menopausal age on breast cancer proneness in this very-low-risk population.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesWALKER, A. R. P. ; WALKER, B. F. ; JONES, J. ; VERARDI, M. ; WALKER, C.
Oxford, UK : Blackwell Publishing Ltd
Published 1985Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. Frequency and severity of nausea and of vomiting during pregnancy, and of pronounced dietary cravings and aversions, were determined in a series of South African rural and urban black, Indian, coloured (European-African-Malay) and white women. Frequency of severe nausea ranged from 3.8% in rural blacks to 19.8% in white women, and of severe vomiting from 3.1% in rural blacks to 17.8% in white and Indian women. Proportions in the other groups were intermediate. Pronounced cravings, claimed by 67–84% in the various groups, included sour, savoury and sweet foods, also fruit and milk. Aversions were claimed by 45–81% of the women in the different groups with meat, fish, coffee and fatty foods, the foods most often avoided. Pica, the consumption of such substances as earth, clay, varied ethnically and regionally; frequency was high in rural and urban black women (44.0% and 38.3%), but much lower (5%) in Indian, coloured and white women.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesWALKER, A. R. P. ; WALKER, B. F. ; SIWEDI, D. ; TSAACSON, C. ; GELDEREN, C. J. ; ANDRONIKOU, A. ; SEGAL, I.
Oxford, UK : Blackwell Publishing Ltd
Published 1985Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. In Soweto, Johannesburg, the incidence of cervical cancer, the most common cancer in black women, is higher than in most white populations but lower than in many other populations. In a series of 210 patients who were diagnosed in 1981 and 1982, 50% had died within 1.6 years of diagnosis, a third of the reported survival time in white patients. The pattern of stage at presentation was similar to, although sometimes later than, those reported for various white communities. Data on patients' age at birth of first child, parity, smoking practice, and socioeconomic status, differed little from those in a control group. Neither these factors, nor availability of medical services, could be correlated with the distressingly short period of survival, which also occurs among urban black patients with breast and ocsophageal cancers. Presumably, unidentified factors linked with low socioeconomic status affect survival time.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesWalker, Alexander R. P. ; Dison, Edna ; Duvenhage, Annette ; Walker, B. Faith ; Friedlander, Ivan ; Aucamp, Vorster
Oxford, UK : Blackwell Publishing Ltd
Published 1981Staff ViewISSN: 1600-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract DMFT scores, total sugar intakes and snack habits were determined in 1918 South African Black pupils (923 rural, 995 urban) and 724 White pupils (English and Afrikaans speaking) aged 16–18 years inclusive. Mean DMFT scores of school groups of Black pupils (both sexes) ranged from 0.9 and 2.0 in rural areas, to 4.2–6.7 in urban areas (where data were far higher than such obtained 7 years ago), and were 9.2 and 10.2 for White pupils. Corresponding mean daily sugar intakes were - rural Blacks, 69 g and 97 g, urban Blacks 118–141 g, respectively (all slightly higher than previously); and Whites 102 g and 123 g. Mean DMFT scores of girls were higher than those of boys; yet while mean sugar intakes of Black girls and boys were somewhat similar, White girls' intakes were much lower than those of White boys. In the ethnic-sex groups studied, mean DMFT scores for pupils in upper, compared with lower, third of sugar intake, were higher in nine of the 14 sub-groups. Mean DMFT scores in upper, compared with lower, third of exposure to snack practices were higher in 11 of the 14 groups. However, most of the differences were slight. In further research, more intensive enquiries should be pursued on roles of ethnic and familial factors, as well as on roles of inter-acting dietary components additional to sugar and sugar-containing foods.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesWalker, Alexander R. P. ; Dison, Edna ; Walker, B. Faith ; Segal, Arlene F.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1600-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract Investigations on caries profile and state of teeth treatment were made on 3752 high school pupils of 16–18 years, namely, rural and urban Black, Indian, Colored (Eur-African-Malay) and White pupils. Rural Blacks had a low mean DMFT of about 2, and a caries-free prevalence of 52%. Of the few with affected teeth, 10% were extracted, none filled, and 90% decayed; i.e. restorative dental attention was virtually nil. Among English and Afrikaans pupils attending Government Schools, mean DMFT was about 10, and caries-free prevalence negligible. Of affected teeth, 13% were extracted, 59% filled and 28% decayed. The situations regarding the urban Black, Indian and Colored groups were intermediate. The Jewish pupils, well-circumstanced and attending private schools, had a mean DMFT of 6.5, moreover 6% were caries-free. Of affected teeth, 1% had been extracted; 93% were filled, and only 6% remained decayed. Since it transpired that the diets of the three White subgroups, cariogenically, were much the same, the advantageous position of the Jewish pupils was judged to be due primarily to their excellent oral hygiene motivation, particularly their demonstrably regular visits to dentists.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesWalker, A. R. P. ; Dison, E. ; Walker, B. F. ; Hart, S. ; Jenkins, T.
Oxford, UK : Blackwell Publishing Ltd
Published 1985Staff ViewISSN: 1600-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract DMFT scores were determined in series of 1) urban Black adolescents (132 boys, 143 girls) aged 16–18 yr, and 2) rural Black mothers (480) aged 20–35 yr. Each series was divided into upper and lower thirds, with respect to DMFT. No relationship was apparent between segments with good versus inferior teeth, and blood groups.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesLosowsky, M. S. ; Kelleher, J. ; Walker, B. E. ; Davies, T. ; Smith, C. L.
Oxford, UK : Blackwell Publishing Ltd
Published 1972Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesSander, P. ; Rezwan, M. ; Walker, B. ; Rampini, S. K. ; Kroppenstedt, R. M. ; Ehlers, S. ; Keller, C. ; Keeble, J. R. ; Hagemeier, M. ; Colston, M. J. ; Springer, B. ; Böttger, E. C.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: Lipoproteins are a subgroup of secreted bacterial proteins characterized by a lipidated N-terminus, processing of which is mediated by the consecutive activity of prolipoprotein diacylglyceryl transferase (Lgt) and lipoprotein signal peptidase (LspA). The study of LspA function has been limited mainly to non-pathogenic microorganisms. To study a potential role for LspA in the pathogenesis of bacterial infections, we have disrupted lspA by allelic replacement in Mycobacterium tuberculosis, one of the world's most devastating pathogens. Despite the presence of an impermeable lipid outer layer, it was found that LspA was dispensable for growth under in vitro culture conditions. In contrast, the mutant was markedly attenuated in virulence models of tuberculosis. Our findings establish lipoprotein metabolism as a major virulence determinant of tuberculosis and define a role for lipoprotein processing in bacterial pathogenesis. In addition, these results hint at a promising new target for therapeutic intervention, as a highly specific inhibitor of bacterial lipoprotein signal peptidases is available.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 0301-0104Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: