Search Results - (Author, Cooperation:B. T. Nixon)
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1P. Li ; S. Banjade ; H. C. Cheng ; S. Kim ; B. Chen ; L. Guo ; M. Llaguno ; J. V. Hollingsworth ; D. S. King ; S. F. Banani ; P. S. Russo ; Q. X. Jiang ; B. T. Nixon ; M. K. Rosen
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-09Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Actin-Related Protein 2-3 Complex/metabolism ; Adaptor Proteins, Signal Transducing/chemistry/metabolism ; Binding Sites ; Biopolymers/chemistry/metabolism ; Fluorescence Recovery After Photobleaching ; HeLa Cells ; Humans ; Ligands ; Membrane Proteins/chemistry/metabolism ; Multiprotein Complexes/*chemistry/*metabolism ; Oncogene Proteins/chemistry/metabolism ; *Phase Transition ; Phosphorylation ; Proline-Rich Protein Domains ; Protein Structure, Quaternary ; Proteins/*chemistry/*metabolism ; *Signal Transduction ; Wiskott-Aldrich Syndrome Protein, Neuronal/chemistry/metabolism ; src Homology DomainsPublished by: -
2A. Chakraborty ; D. Wang ; Y. W. Ebright ; Y. Korlann ; E. Kortkhonjia ; T. Kim ; S. Chowdhury ; S. Wigneshweraraj ; H. Irschik ; R. Jansen ; B. T. Nixon ; J. Knight ; S. Weiss ; R. H. Ebright
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-08-04Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: DNA Polymerase III/*chemistry/drug effects ; Fluorescence Resonance Energy Transfer/methods ; *Gene Expression Regulation, Bacterial ; Protein Conformation ; *Transcription, GeneticPublished by: -
3Staff View
ISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: The Rhizobium melilot genes dctB and dctD positively regulate the expression of dctA, which encodes a C4-dicarboxylate transport protein. Here we characterize an element (UAS) located upstream of dctA that has tandem binding sites for the dctD gene product (DctD). At relatively low concentrations of active DctD, the element activated dctA transcription, but at relatively high concentrations of DctD it was inhibitory. The UAS failed to function when placed further upstream of dctA. Both DctD-binding sites were required for optimal UAS function, despite a 50- to 100-fold difference in binding affinities. Moving the promoter distal binding site 5 bp further upstream was functionally equivalent to its deletion. Based on these data, we hypothesize that the α54 -dependent activator DctD binds co-operatively to the R. meliloti dctA UAS, and that occupancy of both sites is required for maximal activation of dctA.Type of Medium: Electronic ResourceURL: