Search Results - (Author, Cooperation:B. Schmid)

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  1. 1
    K. Mori ; S. M. Weng ; T. Arzberger ; S. May ; K. Rentzsch ; E. Kremmer ; B. Schmid ; H. A. Kretzschmar ; M. Cruts ; C. Van Broeckhoven ; C. Haass ; D. Edbauer
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-02-09
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adaptor Proteins, Signal Transducing/metabolism ; Amyotrophic Lateral Sclerosis/genetics/*metabolism/pathology ; Cerebellum/metabolism/pathology ; DNA Repeat Expansion ; DNA-Binding Proteins/metabolism ; Frontotemporal Lobar Degeneration/genetics/*metabolism/pathology ; Heterozygote ; Hippocampus/metabolism/pathology ; Humans ; Open Reading Frames ; *Protein Biosynthesis ; Proteins/genetics/*metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-05-09
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Arctic Regions ; *Biodiversity ; Carbon/metabolism ; *Carbon Cycle ; *Ecosystem ; Nitrogen/metabolism ; Nitrogen Cycle ; Plants/metabolism ; Tropical Climate
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    D. Zuppinger-Dingley ; B. Schmid ; J. S. Petermann ; V. Yadav ; G. B. De Deyn ; D. F. Flynn
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-10-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Adaptation, Biological ; Asteraceae/physiology ; *Biodiversity ; Biological Evolution ; Biomass ; Fabaceae/physiology ; *Plant Physiological Phenomena ; Poaceae/physiology ; Selection, Genetic ; Time Factors
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2015-10-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Biodiversity ; *Climate ; Climate Change/statistics & numerical data ; Conservation of Natural Resources ; Disasters/statistics & numerical data ; Droughts ; *Ecosystem ; Grassland ; Human Activities ; *Plant Physiological Phenomena
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2011-08-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Biodiversity ; Ecology/methods ; *Ecosystem ; Extinction, Biological ; Models, Biological ; Plant Development ; *Plant Physiological Phenomena ; *Plants/classification ; Poaceae ; Species Specificity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Type of Medium:
    article
    Publication Date:
    1980
    Keywords:
    Empirische Untersuchung ; Förderung ; Arbeitswelt ; Berufswahl ; Handwerk ; Gehirnschädigung ; Rehabilitation ; Grafische Darstellung ; Theoretische Schrift ; Geistig behinderter Mensch
    In:
    Die Rehabilitation, Bd. 19 (1980) H. 2, S. 73-83, 0034-3536
    Language:
    German
    FIS Bildung Literaturdatenbank
  7. 7
    Schmid, B. [Verfasser]

    Published 1995
    Staff View
    Type of Medium:
    article
    Publication Date:
    1995
    Keywords:
    Lehrplan ; Berufsausbildung ; Diätassistent
    In:
    Die Ernährung, Bd. 19 (1995) H. 12, 2 S., 0250-1554
    Language:
    German
    FIS Bildung Literaturdatenbank
  8. 8
  9. 9
    Schmid, B. ; Hälg, B. ; Furrer, A. ; Urland, W. ; Kremer, R.

    [S.l.] : American Institute of Physics (AIP)
    Published 1987
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The crystal structures of PrX3 (X=Br, Cl) and particularly the detailed coordination of the halides X have been studied by neutron diffraction on polycrystalline samples in the temperature range between 4.2 and 293 K. Furthermore, the crystalline electric fields (CEF) in the two compounds have been investigated by inelastic neutron scattering experiments on single-crystal samples. The observed CEF transitions have been identified according to the transition matrix elements and the polarization factor in the neutron cross section, which allowed an unambiguous determination of the four CEF parameters for hexagonal symmetry. The energetic ordering of the CEF levels in PrBr3 and PrCl3 are considerably different which can be understood in terms of the different geometric coordination of the halides determined from the diffraction results.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Jensen-Jarolim, E. ; Schmid, B. ; Bernier, F. ; Berna, A. ; Kinaciyan, T. ; Focke, M. ; Ebner, C. ; Scheiner, O. ; Boltz-Nitulescu, G.

    Oxford, UK : Munksgaard International Publishers
    Published 2002
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background:  Germins and the related germin-like proteins (GLPs) are glycoproteins expressed in many plants in response to biotic and abiotic stress. To test the potential impact of germins and GLPs, recombinant germin from Triticum aestivum (tGermin) and GLPs from Arabidopsis thaliana (tGLP), both produced in transformed tobacco plants, were used.Methods:  Sera from 82 patients with type I allergy to birch, grass or mugwort pollen and/or wheat were tested in immunoblot for IgE binding to tGermin and tGLP, and the IgE reactivity after chemical and enzymatic deglycosylation was analysed. The biological activity of tGermin and tGLP was determined in a histamine release assay and in skin prick testing (SPT).Results:  In an immunoblotting assay, 24 out of 82 tested sera (29.26%) from allergic patients showed IgE-binding to tGermin, and 18 of these sera (21.95%) displayed also IgE-binding to tGLP. The deglycosylation experiments indicated that glycan moieties contribute significantly to the IgE-binding of tGermin and tGLP. Both tGermins and tGLP induced specifically histamine release in an invitro assay as well as in SPT.Conclusion:  Our in vitro and in vivo findings demonstrate that germin and GLPs are capable to bind IgE most likely via carbohydrate determinants, and represent allergenic molecules.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Stocker, R. ; Körner, CH. ; Schmid, B. ; Niklaus, P. A. ; Leadley, P. W.

    Oxford, UK : Blackwell Science, Ltd
    Published 1999
    Staff View
    ISSN:
    1365-2486
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Energy, Environment Protection, Nuclear Power Engineering
    Geography
    Notes:
    The relationship between plant species diversity and ecosystem CO2 and water vapour fluxes was investigated for planted calcareous grassland communities composed of 5, 12, or 32 species assembled from the native plant species pool. These diversity manipulations were done in factorial combination with a CO2 enrichment experiment in order to investigate the degree to which ecosystem responses to elevated CO2 are altered by a loss of plant diversity. Ecosystem CO2 and H2O fluxes were measured over several 24-h periods during the 1994 and 1995 growing seasons. Ecosystem CO2 assimilation on a ground area basis decreased with decreasing plant diversity in the first year and this was related to a decline in above-ground plant biomass. In the second year, however, CO2 assimilation was not affected by diversity, and this corresponded to the disappearance of a diversity effect on above-ground biomass. Irrespective of diversity treatment, CO2 assimilation on a ground area basis was linearly related to peak above-ground biomass in both years. Elevated CO2 significantly increased ecosystem CO2 assimilation in both years with no interaction between diversity and CO2 treatment, and no corresponding increase in above-ground biomass. There were no significant effects of diversity on water vapour flux, which was measured only in the second year. There were indications of a small CO2 effect on water vapour flux (3–9% lower at elevated CO2 depending on the light level). Our findings suggest that decreasing plant species diversity may substantially decrease ecosystem CO2 assimilation during the establishment of such planted calcareous grassland communities, but also suggest that this effect may not persist. In addition, we find no evidence that plant species diversity alters the response of ecosystem CO2 assimilation to elevated CO2.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Bohle, B. ; Radakovics, A. ; Lüttkopf, D. ; Jahn-Schmid, B. ; Vieths, S. ; Ebner, C.

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background IgE antibodies specific for the major birch-pollen allergen, Bet v 1, cross-react with homologous allergens in particular foods, e.g. apples, carrots and hazelnuts. In a high number of tree pollen-allergic individuals, this cross-reactivity causes clinical symptoms, commonly known as the ‘birch-fruit-syndrome’.Objective To characterize the T cell response to the Bet v 1-related major allergen in hazelnuts, Cor a 1.04, and its cellular cross-reactivity with Bet v 1 and the homologous hazel pollen allergen, Cor a 1.Methods Using recombinant Cor a 1.04, T cell lines (TCL) and T cell clones (TCC) were established from peripheral blood mononuclear cells of tree pollen-allergic patients with associated food allergy. T cell epitopes were determined using overlapping synthetic peptides in Cor a 1.04-reactive TCL and TCC. In parallel, reactivity to Bet v 1 and Cor a 1 was tested.Results In total, 20 distinct T cell epitopes on the hazelnut allergen were identified. Several Cor a 1.04-specific TCL and TCC reacted with pollen allergens albeit less pronounced than with the hazelnut allergen. Several Cor a 1.04-specific TCC did not react with pollen allergens. Interestingly, these clones were found to react with the Bet v 1-related major allergen in carrots, Dau c 1. The cellular cross-reactivity between both food allergens could be associated with the most frequently recognized T cell epitope of Cor a 1.04, Cor a 1.04142–153.Conclusions The major hazelnut allergen cross-reacts with the major allergens of birch and hazel pollen but apparently contains a relevant T cell epitope not shared with pollen allergens. Our finding may have important implications for the specific immunotherapy of tree pollen-allergic patients suffering from concomitant hazelnut allergy.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Jahn-Schmid, B. ; Harwanegg, C. ; Hiller, R. ; Bohle, B. ; Ebner, C. ; Scheiner, O. ; Mueller, M. W.

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background The availability of recombinant allergens and recent advances in biochip technology led to the development of a novel test system for the detection of allergen-specific IgE.Objective To test the performance of this allergen microarray in a serological analytical study.Methods Standard allergens contained in grass pollen (Phl p 1, Phl p 2, Phl p 5 and Phl p 6) and tree pollen (Bet v 1 and Bet v 2) were used as a model system. The detection of allergen-specific serum IgE using microarrays was compared with standard test systems: CAP/RAST and an in-house ELISA. In order to test the analytical sensitivity of the assays, geometric dilutions of a serum pool containing high levels of pollen-specific IgE from allergic individuals were tested in each system. To assess the analytical specificity, the sera of 51 patients with presumptive allergic symptoms were collected before diagnosis. Thereafter, the results for grass/tree-pollen-specific IgE were compared.Results The microarray has a good dynamic range similar to the CAP/RAST system. Microarray and ELISA showed comparable analytical sensitivity exceeding the CAP/RAST system. With respect to the analytical specificity, no significant cross-reactivity of the allergens was observed. For two of the allergens tested, weak positive signals were detected in the microarray test system, whereas they were not detectable by CAP/RAST.Conclusion A good correlation of presently used methods to detect serum IgE and the novel microarray test system was observed. As a next step, a careful validation of this method for a multitude of allergens and a thorough clinical evaluation has to be provided.Microarray testing of allergen-specific IgE can be presumed to be the method of choice for a prospective component-resolved diagnosis of Type I allergy, and the basis for the design and monitoring of a patient-tailored specific immunotherapy in the future.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Schmid, B. ; Ostermann, G. ; Kertscher, H.-P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-3084
    Keywords:
    chemical synthesis ; human platelet aggregation ; platelet-activating factor (PAF) species
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Schmid, B. ; Anke, T. ; Wolf, H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-5793
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
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