Search Results - (Author, Cooperation:B. R. Brooks)
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1H. X. Deng ; W. Chen ; S. T. Hong ; K. M. Boycott ; G. H. Gorrie ; N. Siddique ; Y. Yang ; F. Fecto ; Y. Shi ; H. Zhai ; H. Jiang ; M. Hirano ; E. Rampersaud ; G. H. Jansen ; S. Donkervoort ; E. H. Bigio ; B. R. Brooks ; K. Ajroud ; R. L. Sufit ; J. L. Haines ; E. Mugnaini ; M. A. Pericak-Vance ; T. Siddique
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-08-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Age of Onset ; Aging ; Amino Acid Sequence ; Amyotrophic Lateral Sclerosis/complications/*genetics/pathology ; Base Sequence ; Cell Cycle Proteins/analysis/*genetics ; Cell Line ; Child ; DNA-Binding Proteins/metabolism ; Dementia/*complications/*genetics/pathology ; Female ; Genes, Dominant/*genetics ; Genes, X-Linked/*genetics ; Hippocampus/metabolism ; Humans ; Male ; Molecular Sequence Data ; Mutation/*genetics ; Pedigree ; Proteasome Endopeptidase Complex/metabolism ; Spinal Cord/metabolism ; Ubiquitin/metabolism ; Ubiquitins/analysis/*geneticsPublished by: -
2Zegler, M. G. ; Lake, C. R. ; Wood, J. H. ; Brooks, B. R. ; Ebert, M. H.
Oxford, UK : Blackwell Publishing Ltd
Published 1977Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
3Hemley, R. J. ; Brooks, B. R. ; Karplus, M.
College Park, Md. : American Institute of Physics (AIP)
Published 1986Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Vibrational force fields for the ground states of 1,3-butadiene, 1,3,5-hexatriene, and 1,3,5,7-octatetraene are calculated from extended Pariser–Parr–Pople CI theory. For the ground state of butadiene, the principal π-system force constants are compared to those determined by empirical, other semiempirical, and ab initio methods. The calculated vibrational frequency shifts for a series of deuterium substituted butadienes are found to be in good agreement with experiment. Trends in the principal π-system force constants of the polyenes for the ground states of ethylene through octatetraene are described, including the effects of introducing cis linkages in the polyene chain and of using single- vs single-plus-double-excitation CI. Correlations between the force constants and the calculated vibrational frequencies are discussed, and current assignments of the vibrational spectra of the polyenes are examined in view of the theoretical results.Type of Medium: Electronic ResourceURL: -
4Raghunathan, G. ; Seetharamulu, P. ; Brooks, B. R. ; Guy, H. R.
New York, NY : Wiley-Blackwell
Published 1990Staff ViewISSN: 0887-3585Keywords: molecular modeling ; energy calculations ; δ-hemolysin ; melittin ; crystal packing ; raft ; bilayer ; membrane insertion ; channel formation ; Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: MedicineNotes: Molecular modeling and energy calculations have been used to study how δ-hemolysin and melittin helices may aggregate on membrane surfaces and insert through membranes to form channels. In these models adjacent antiparallel amphipathic helices form planar “raft” structures, in which one surface is hydrophobic and the other hydrophilic. Models of δ-hemolysin crystal structure were developed using these “rafts.” These models are based on the unit cell constants and the crystal symmetry obtained from the preliminary crystal data. Energy calculations favor channel models of δ-hemolysin with six or eight monomers per channel.Additional Material: 7 Ill.Type of Medium: Electronic ResourceURL: -
5Raghunathan, G. ; Seetharamula, P. ; Brooks, B. R. ; Gua, H. R.
New York, NY : Wiley-Blackwell
Published 1991Staff ViewISSN: 0887-3585Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: MedicineType of Medium: Electronic ResourceURL: