Search Results - (Author, Cooperation:B. Pichler)

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  1. 1
    H. Ko ; S. B. Hofer ; B. Pichler ; K. A. Buchanan ; P. J. Sjostrom ; T. D. Mrsic-Flogel
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-04-12
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Calcium/chemistry ; Calcium Signaling/physiology ; Computer Simulation ; Electrical Synapses/*physiology ; Mice ; Mice, Inbred C57BL ; Nerve Net/*physiology ; Patch-Clamp Techniques ; Photic Stimulation ; Pyramidal Cells/physiology ; Visual Cortex/*physiology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    K. Angelo ; E. A. Rancz ; D. Pimentel ; C. Hundahl ; J. Hannibal ; A. Fleischmann ; B. Pichler ; T. W. Margrie
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-07-24
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Female ; Gene Expression Profiling ; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels ; Ion Channels/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Models, Neurological ; Nerve Net/*physiology ; Olfactory Bulb/*cytology/*physiology ; Potassium Channels ; Receptors, Odorant/metabolism ; Smell/*physiology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-01-03
    Publisher:
    The Society of Nuclear Medicine (SNM)
    Print ISSN:
    0022-3123
    Topics:
    Medicine
    Published by:
    http://www.snm.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-07-03
    Publisher:
    The Society of Nuclear Medicine (SNM)
    Print ISSN:
    0022-3123
    Topics:
    Medicine
    Published by:
    http://www.snm.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    ISSN:
    1432-1238
    Keywords:
    Key words Noninvasive mechanical ventilation ; Pressure support ventilation ; Continuous positive airways pressure ; Weaning criteria ; Respiratory failure
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Objective: To investigate the effects of noninvasive positive pressure ventilation (NPPV) on pulmonary gas exchange, breathing pattern, intrapulmonary shunt fraction, oxygen consumption, and resting energy expenditure in patients with persistent acute respiratory failure but without chronic obstructive pulmonary disease (COPD) after early extubation. Design: Prospective study. Setting: Multidisciplinary intensive care unit of a university hospital. Patients: 15 patients after prolonged mechanical ventilation (〉 72 h) with acute respiratory insufficiency after early extubation. Interventions: Criteria for early extubation were arterial oxygen tension (PaO2) L 40 mm Hg (fractional inspired oxygen 0.21), arterial carbon dioxide tension (PaCO2) K 55 mm Hg, pH 〉 7.32, respiratory rate K 40 breaths per min, tidal volume (VT) L 3 ml/kg, rapid shallow breathing index K 190 and negative inspiratory force L 20 cmH2O. After extubation, two modes of NPPV were applied [continuous positive airway pressure (CPAP) of 5 cmH2O and pressure support ventilation (PSV) with 15 cmH2O pressure support]. Measurements and main results: Oxygenation and ventilatory parameters improved during both modes of NPPV (p 〈 0.05): increase in PaO2 of 11 mm Hg during CPAP and 21 mm Hg during PSV; decrease in intrapulmonary shunt fraction of 7 % during CPAP and 12 % during PSV; increase in tidal volume of 1 ml/kg during CPAP and 4 ml/kg during PSV; decrease in respiratory rate 6 breaths/min during CPAP and 9 breaths/min during PSV. Oxygen consumption (15 % during CPAP, 22 % during PSV) and resting energy expenditure (12 % during CPAP, 20 % during PSV) were reduced (p 〈 0.05). PaCO2 decreased, whereas minute ventilation and pH increased during PSV (p 〈 0.05). The median duration of NPPV was 2 days. Two patients had to be reintubated. Conclusions: In non-COPD patients with persistent acute respiratory failure after early extubation, NPPV improved pulmonary gas exchange and breathing pattern, decreased intrapulmonary shunt fraction, and reduced the work of breathing.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s001340051084

    Articles: DFG German National Licenses