Search Results - (Author, Cooperation:B. Nilsson)
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1Latest Papers from Table of Contents or Articles in PressA. Campeau, K. Bishop, M. B. Nilsson, L. Klemedtsson, H. Laudon, F. I. Leith, M. Öquist, M. B. Wallin
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-01-06Publisher: Wiley-BlackwellPrint ISSN: 0148-0227Topics: BiologyGeosciencesPublished by: -
2Latest Papers from Table of Contents or Articles in PressH. N. Chapman ; P. Fromme ; A. Barty ; T. A. White ; R. A. Kirian ; A. Aquila ; M. S. Hunter ; J. Schulz ; D. P. DePonte ; U. Weierstall ; R. B. Doak ; F. R. Maia ; A. V. Martin ; I. Schlichting ; L. Lomb ; N. Coppola ; R. L. Shoeman ; S. W. Epp ; R. Hartmann ; D. Rolles ; A. Rudenko ; L. Foucar ; N. Kimmel ; G. Weidenspointner ; P. Holl ; M. Liang ; M. Barthelmess ; C. Caleman ; S. Boutet ; M. J. Bogan ; J. Krzywinski ; C. Bostedt ; S. Bajt ; L. Gumprecht ; B. Rudek ; B. Erk ; C. Schmidt ; A. Homke ; C. Reich ; D. Pietschner ; L. Struder ; G. Hauser ; H. Gorke ; J. Ullrich ; S. Herrmann ; G. Schaller ; F. Schopper ; H. Soltau ; K. U. Kuhnel ; M. Messerschmidt ; J. D. Bozek ; S. P. Hau-Riege ; M. Frank ; C. Y. Hampton ; R. G. Sierra ; D. Starodub ; G. J. Williams ; J. Hajdu ; N. Timneanu ; M. M. Seibert ; J. Andreasson ; A. Rocker ; O. Jonsson ; M. Svenda ; S. Stern ; K. Nass ; R. Andritschke ; C. D. Schroter ; F. Krasniqi ; M. Bott ; K. E. Schmidt ; X. Wang ; I. Grotjohann ; J. M. Holton ; T. R. Barends ; R. Neutze ; S. Marchesini ; R. Fromme ; S. Schorb ; D. Rupp ; M. Adolph ; T. Gorkhover ; I. Andersson ; H. Hirsemann ; G. Potdevin ; H. Graafsma ; B. Nilsson ; J. C. Spence
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Crystallography, X-Ray/instrumentation/*methods ; Lasers ; Models, Molecular ; Nanoparticles/*chemistry ; Nanotechnology/instrumentation/*methods ; Photosystem I Protein Complex/*chemistry ; Protein Conformation ; Time Factors ; X-RaysPublished by: -
3Latest Papers from Table of Contents or Articles in PressM. M. Seibert ; T. Ekeberg ; F. R. Maia ; M. Svenda ; J. Andreasson ; O. Jonsson ; D. Odic ; B. Iwan ; A. Rocker ; D. Westphal ; M. Hantke ; D. P. DePonte ; A. Barty ; J. Schulz ; L. Gumprecht ; N. Coppola ; A. Aquila ; M. Liang ; T. A. White ; A. Martin ; C. Caleman ; S. Stern ; C. Abergel ; V. Seltzer ; J. M. Claverie ; C. Bostedt ; J. D. Bozek ; S. Boutet ; A. A. Miahnahri ; M. Messerschmidt ; J. Krzywinski ; G. Williams ; K. O. Hodgson ; M. J. Bogan ; C. Y. Hampton ; R. G. Sierra ; D. Starodub ; I. Andersson ; S. Bajt ; M. Barthelmess ; J. C. Spence ; P. Fromme ; U. Weierstall ; R. Kirian ; M. Hunter ; R. B. Doak ; S. Marchesini ; S. P. Hau-Riege ; M. Frank ; R. L. Shoeman ; L. Lomb ; S. W. Epp ; R. Hartmann ; D. Rolles ; A. Rudenko ; C. Schmidt ; L. Foucar ; N. Kimmel ; P. Holl ; B. Rudek ; B. Erk ; A. Homke ; C. Reich ; D. Pietschner ; G. Weidenspointner ; L. Struder ; G. Hauser ; H. Gorke ; J. Ullrich ; I. Schlichting ; S. Herrmann ; G. Schaller ; F. Schopper ; H. Soltau ; K. U. Kuhnel ; R. Andritschke ; C. D. Schroter ; F. Krasniqi ; M. Bott ; S. Schorb ; D. Rupp ; M. Adolph ; T. Gorkhover ; H. Hirsemann ; G. Potdevin ; H. Graafsma ; B. Nilsson ; H. N. Chapman ; J. Hajdu
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Electrons ; Hot Temperature ; Lasers ; Mimiviridae/*chemistry ; Photons ; Time Factors ; X-Ray Diffraction/*instrumentation/*methods ; X-RaysPublished by: -
4Articles: DFG German National LicensesScharen, M. J. ; Skoglund, D. L. ; Forse, R. J. ; Nilsson, B. J. L. ; Hammond, R. B. ; Olson, W. L.
[S.l.] : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: We present two processes for the fabrication of bondable, low-loss ohmic contacts to high-temperature superconductor thin-film devices. Contact resistances at both high and low frequencies are comparable—between 5.0×10−7 and 2.0×10−5 Ω cm2 at 77 K. We demonstrate that losses at low frequency correlate with losses up to 10 GHz. Destructive bond pull strengths for 25-μm-diam, thermosonically attached gold wire average between 5.0 and 8.0 g force, exceeding the industry standard of 3.0 g force. Preliminary results also show that contact resistance as low as 1.7×10−8 Ω cm2 are attainable with annealing. These processes satisfy a pressing need for fabrication of reliable, low-loss ohmic contacts required for the development and production of high-performance passive microwave devices based on high-Tc superconducting thin-film materials.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesSjövall, K. ; Nilsson, B. ; Einhorn, N.
238 Main Street, Cambridge, MA 02142, USA : Blackwell Scientific Publications
Published 1994Staff ViewISSN: 1525-1438Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The significance of tumor spill in the early stages of ovarian carcinoma has been the subject of controversy. Since rupture of the capsule of the tumor may occur in several different ways, we analyzed all cases of early ovarian cancer treated at Radiumhemmet, Stockholm, Sweden, during the period 1974–1986, in which possible spill of tumor cells was catalogued in different groups. In 247 out of 394 patients (62%) the risk of spill had to be considered. There was no difference in survival between patients whose tumors had intact capsules and patients in whom rupture occurred during surgery—78% and 85%, respectively. On the other hand, a significant difference in survival was found between patients in whom rupture occurred before surgery and those with intraoperative rupture—59% and 85%, respectively. The conclusion can be drawn that manipulation during surgery which results in puncture or rupture does not have a negative influence on the outcome for the patients.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesHellström, A.-C. ; Frankendal, B. ; Nilsson, B. ; Pettersson, F. ; Silfverswärd, C. ; Auer, G.
Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Science Inc.
Published 1996Staff ViewISSN: 1525-1438Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Short- and long-time survivors among patients with primary fallopian tube carcinoma (PFTC) were studied with respect to prognosis predicting factors. Within the Radiumhemmets series 35 patients died within 2 years and they were compared with 27 patients surviving 8 years or more. All tumours were aneuploid. The two groups had different p53 immunoreactivity (P = 0.05). The prognostic influence of FIGO stage, proliferative activity (MIB-I), tumor angiogenesis (F8) and p53 immunoreactivity was studied in all stages. MIB-1, F8, and p53 immunoreactivity showed no significant correlation to survival. FIGO stage was significantly correlated to survival (P = 0.001). Increasing proliferative activity correlated to poor survival in a multivariate analysis of stage I (P = 0.015). Nine out of 19 stage I patients are still alive with a median survival of 22 years (11–32). Six of the survivors (66%) did not receive chemotherapy and underwent incomplete surgery. Two patients in stage IV are still alive after 12 and 13 years respectively. The only difference in biological parameters in the two survival groups was the absence of p53 mutations in the long-time survivors.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesEinhorn, N. ; Nilsson, B. ; Holmberg, K. ; Lambert, B. ; Einhorn, S.
Suite 500, 5th Floor, 238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Science Inc.
Published 1996Staff ViewISSN: 1525-1438Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Patients with ovarian carcinoma show an increased incidence of second tumors. The reason for this increase in incidence is not known. One hundred and ten ovarian cancer patients, in which half received an alkylating agent (Melphalan) and the rest received no chemotherapy, were studied to evaluate the role of chemotherapy in the development of second malignancies. In 55 chemotherapy treated patients 17 second tumors developed which can be compared with five second tumors developing in 55 patients not receiving chemotherapy (P = 0.017). Cytogenetic analysis of peripheral blood cells performed on the 55 chemotherapy treated patients showed an increased frequency of chromosome aberrations compared with healthy controls, but no difference was observed between patients developing second tumors and those who did not. No statistically significant difference in the incidence of close relatives with cancer was observed in patients with second tumors as compared to cases remaining free of new malignancies. In conclusion the given chemotherapy seems to be the major cause for second tumors in this cohort of patients with ovarian cancer.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesHellström, A.-C. ; Silfverswärd, C. ; Nilsson, B. ; Pettersson, F.
238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Scientific Publications
Published 1994Staff ViewISSN: 1525-1438Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A histopathologic and clinical review of the Radiumhemmet series of primary fallopian tube carcinoma (PFTC) treated from 1923 to 1991 revealed that 128 cases fulfilled the diagnostic criteria for PFTC. These cases were staged according to the new FIGO staging rules for PFTC. Survival was studied with respect to prognostic factors such as age, stage, histologic subgroups, degree of differentiation and mode of treatment. The mean age at diagnosis was 56 years. Seventy-four per cent were found to be in stage Ia–IIa and 26 % in stage III–IV. Forty-five per cent were nulliparous and 22 % had evidence of previous pelvic inflammatory disease. Treatment modalities changed during the studied period. Thirty-three per cent of patients underwent surgery with total abdominal hysterectomy and bilateral salpingo-oophorectomy while 67 % were incompletely operated. A trend towards improvement in results was noticed—however, it was not statistically significant. Among the 14 prognostic variables tested in the multivariate analysis the first in rank were stage (P = 0.001) and degree of differentiation of the tumors (P = 0.070). Patients receiving chemotherapy had superior survival rates compared with those without chemotherapy (P = 0.0006) and patients with cisplatinum-containing chemotherapy did better than those without cisplatin.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. The metabolic effects of oestrogen therapy are influenced by the route of administration. Compared with oral treatment, percutaneous administration may have theoretical advantages with respect to liver metabolism, but there are also potential disadvantages related to the specific kinetics of this route. The increase of SHBG binding capacity is much less pronounced, which might result in excess amounts of unbound, biologically-active steroid during therapy. The serum concentrations of unbound 17β-oestradiol were calculated in two groups of postmenopausal women during replacement therapy with equivalent amounts of oral and percutaneous oestrogen. A highly significant and quite similar increase of the free fraction as well as in total 17β-oestradiol was found in both groups of women, in spite of the fact that SHBG binding capacity was unchanged during percutaneous therapy. Albumin binding and the total serum concentration of 17β-oestradiol were found to be more important for the regulation of unbound steroid concentration than variations in SHBG binding capacity. In conclusion, there was no evidence that percutaneous administration per se would carry an increased risk of over-treatment.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Amniotic fluid cells provide important information about the fetus. Studies of the surface ultrastructure of such cells identified four cell populations in midgestational fluids. A parallel study of tissue surfaces in contact with or communicating with the amniotic fluid showed that some tissues made no contribution to the cell populations, while others contributed extensively. Two principal cell shedding mechanisms were found in mid-trimester—exfoliation of whole cells and detachment of cellular fragments. The latter mechanism was observed from skin and umbilical cords during a limited period in mid-pregnancy. The majority of cells were derived from exfoliation of squamous epithelia.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesMichaëlsson, G. ; Gerdén, B. ; Hagforsen, E. ; Nilsson, B. ; Pihl-Lundin, I. ; Kraaz, W. ; Hjelmquist, G. ; Lööf, L.
Oxford, UK : Blackwell Science Ltd
Published 2000Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: In a previous screening study, 16% of patients with psoriasis had IgA and/or IgG antibodies to gliadin (AGA). The aim of the present study was to evaluate the effect of a gluten-free diet (GFD) in 33 AGA-positive and six AGA-negative psoriasis patients. Of the 33 AGA-positive patients, two had IgA antibodies to endomysium (EmA) and 15 an increased number of lymphocytes in the duodenal epithelium, but in some this increase was slight. Two patients had villous atrophy. A 3-month period on a GFD was followed by 3 months on the patient’s ordinary diet. The severity of psoriasis was evaluated with the psoriasis area and severity index (PASI). The examining dermatologists were unaware of the EmA and duodenal biopsy results throughout the study. Thirty of the 33 patients with AGA completed the GFD period, after which they showed a highly significant decrease in mean PASI. This included a significant decrease in the 16 AGA-positive patients with normal routine histology in duodenal biopsy specimens. The AGA-negative patients were not improved. After GFD, the AGA values were lower in 82% of those who improved. There was a highly significant decrease in serum eosinophil cationic protein in patients with elevated AGA. When the ordinary diet was resumed, the psoriasis deteriorated in 18 of the 30 patients with AGA who had completed the GFD period. In conclusion, psoriasis patients with raised AGA might improve on a GFD even if they have no EmA or if the increase in duodenal intraepithelial lymphocytes is slight or seemingly absent.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesFolbergrova, J. ; Nilsson, B. ; Nordström, C.-H. ; Siesjö, B. K.
Oxford, UK : Blackwell Publishing Ltd
Published 1978Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Neurochemical studies of induced seizures have provided much information on metabolic capacity in the brain. However, there is no general agreement on the magnitude of changes in cerebral metabolic rate. Presumably, differences in results depend both on the models of epilepsy used and on methodological factors.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A methodological study of the influence of local stasis and mechanical pressure on the continuous transcutaneous oxygen tension electrode (tcPO2 electrode) during intrapartum monitoring is presented. No effect of mechanical pressure up to 7.3 kPa (55 mm Hg) on the electrode membrane was found. Reduced blood flow in the capillaries of the tissue beneath the electrode caused by stasis or pressure effect resulted, below a certain threshold value, in tcPO2 decrease. The results emphasize that an attempt to differentiate between a methodologically caused decrease and a decrease due to impaired oxygenation must be made when evaluating the absolute fetal arterial oxygen tension from fetal tcPO2. The consistently observed decrease in relative local perfusion (‘flow’) may be a help in this respect.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesSalto-Tellez, M. ; Zhang, D. ; Chiu, L. L. ; Wang, S. C. ; Nilsson, B. ; Koay, E. S. C.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1365-2303Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Examination of cytological samples of cancer to suggest a possible primary site of origin is one of the commonest and most difficult tasks of diagnostic cytopathologists. Currently, both cytomorphology and immunocytochemistry are the main approaches to this diagnostic dilemma. We report the application of microsatellite analysis in cytological samples in a patient with a primary colonic tumour and two subsequent lung nodules, which were suspected on CT scans of the chest, and compared the findings with those obtained with conventional immunocytochemistry. The molecular results were in agreement with the radiological impression and conflicted with the immunocytochemistry. We conclude that immunocytochemical and molecular biology approaches to the diagnosis of tumours may give rise to contradictory results.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesNILSSON, U. R. ; LARM, O. ; NILSSON, B. ; STORM, K.-E. ; ELWING, H. ; EKDAHL, K. NILSSON
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: In recent years, conjugation of heparin to biomaterials has been shown to improve its biocompatibility. The purpose of the present work was to compare complement activation and binding of C3 to unmodified and heparin-treated polystyrene surfaces of microtitre plates. When polystyrene was incubated with human serum, C3 was deposited on the surface by both adsorption and binding dependent on activation of the classical (CPW) and alternative (APW) pathways After end-point attachment of heparin, significant C3 deposition, although at reduced levels, occurred only by CPW-mediated mechanisms. while adsorption and APW -mediated binding were strongly reduced. Generally, the modified surface bound lower amounts of protein, e.g. serum albumin and IgG, than the unmodified. By contrast, it had increased affinity for Clq which leads to binding of Cl and activation of complement via the CPW. Nevertheless, the net effect of the surface modification on the complement reaction was an overall reduction of C3 binding due to obliteration of APW. This can be related to an enhanced factor H/I-dependent down-regulation of C3b and to the lowered protein-adsorbing property of the surface, both of which have inhibitory effects on APW and on the C3 shunt-dependent activation of the complement system.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Various polyclonal activating substances have been shown to stimulate human chronic lymphatic leukaemia (CLL) cells lo undergo blast transformation, to divide and to secrete monoclonal immunoglobulin. CLL cells from different patients show distinct response patterns to these ligands. We have statistically analysed these response patterns and found that responses to certain ligands demonstrate covariance; that is, a high response to one ligand is statistically associated with a high response to another ligand. A factor analysis of these data on the basis of responses of CLL cells from twenty-one patients and from the use of five different ligands in three different concentrations has shown that as few as two factors can account for as much as 63% of the total variance of these responses. On the assumption that these two factors were T-cell dependency of CLL responses and stage of maturity of the responding CLL cell, we have formulated a theory that explains the basis for this functional marker system for CLL cells. Its possible application to the characterization of individual CLL clones has been discussed.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesFolbergrová, J. ; Nilsson, B. ; Sakabe, T. ; Siesjö, B. K.
Oxford, UK : Blackwell Publishing Ltd
Published 1981Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: In order to study the influence of hypoxia on cyclic nucleotides in the brain, we reduced arterial Po, for 15–30 min in lightly anaesthetised and artificially ventilated rats to obtain values ranging from about 45 to about 10 mm Hg. In an additional group (arterial Po2 18–22 mm Hg), the tissue hypoxia was aggravated by moderate arterial hypotension (mean arterial blood pressure about 80 mm Hg). In all animals, electrocortical activity was recorded. Cyclic GMP concentrations in cerebral cortex were unchanged in all groups but one. In that group, in which tissue hypoxia was severe enough to induce a suppression-burst EEG pattern and a measurable reduction in the adenylate energy charge, cyclic GMP concentrations were slightly increased (p 〈 0.05). Cyclic AMP concentrations remained unaltered at all degrees of hypoxia studied. It is concluded that changes in cyclic nucleotides in brain tissue occur first at such severe degrees of hypoxia of the duration studied that function and metabolism are profoundly altered.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1600-0714Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Carbohydrate analyses were performed on dental plaque collected from the teeth of irradiated monkeys, non-irradiated monkeys and a group of Streptococcus mutans free animals, all of which were fed the same standard cariogenic diet. Glucose was the predominant sugar constituent in plaque and was detected in highest concentration in the irradiated animals. Small amounts of pentoses and other hexoses were also present. Plaque from irradiated animals contained, by comparison with the other groups, higher levels of Strep, mutans and lower levels of Streptococcus sanguis and Actinomyces.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesJönsson, D. ; Wahlin, Å. ; Idvall, I. ; Johnsson, I. ; Bratthall, G. ; Nilsson, B-O.
Oxford, UK : Munksgaard International Publishers
Published 2005Staff ViewISSN: 1600-0765Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background: It is important to clarify the biological function of the female sex hormones estrogen and progesterone in periodontal ligament cells, as these hormones may affect periodontal health. We have previously shown that human periodontal ligament cells express estrogen receptor β (ERβ) but not ERα, whereas human breast cancer cells (MCF7) express both ERα and ERβ. Data on progesterone receptor (PgR) expression in human periodontal ligament cells have not been reported.Objectives: Determine PgR expression in human periodontal ligament and MCF7 cells and to investigate how estrogen affects DNA and collagen synthesis in these two cell types showing different pattern of expression for ERα and β.Methods: Periodontal ligament cells were obtained from the periodontal ligament of premolars extracted for orthodontic reasons and MCF7 cells from the American Type Culture Collection (ATCC). PgR expression was determined by immunocytochemistry. DNA and collagen synthesis was determined by [3H]thymidine and l-[3H]proline incorporation, respectively.Results: PgR immunoreactivity was observed in nuclei of MCF7 but not periodontal ligament cells. Treatment with estrogen (17β-estradiol, E2) at physiological concentrations for 24 h stimulated DNA synthesis by more than two times in MCF7 cells, whereas there was no effect on periodontal ligament cell DNA synthesis. The ER blocker ICI 182780 fully reversed the stimulatory effect of E2. Not only short-term (24 h) but also long-term (5 days) treatment with E2 lacked effect on DNA synthesis in periodontal ligament cells. Neither periodontal ligament cell viability nor collagen synthesis was affected by E2 treatment. Identical results were observed in periodontal ligament cells from male and female subjects.Conclusions: Human MCF7 but not periodontal ligament cells express PgR, suggesting that progesterone via PgR affects MCF7 but not periodontal ligament cells. Further, estrogen stimulates breast cancer MCF7 cell proliferation, whereas it has no effect on proliferation of periodontal ligament cells, probably reflecting cell type specific ER expression pattern in these two cell types.Type of Medium: Electronic ResourceURL: