Search Results - (Author, Cooperation:B. Morgan)

2018-05-11

American Chemical Society (ACS)

0022-3263

1520-6904

Chemistry and Pharmacology

2018-07-06

American Society of Hematology (ASH)

0006-4971

1528-0020

Biology

Medicine

Multiple Myeloma, Lymphoid Neoplasia, Clinical Trials and Observations

2018-06-05

The American Association of Immunologists (AAI)

0022-1767

1550-6606

Medicine

2014-07-24

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Animals ; Aquaculture ; Australia ; Cost-Benefit Analysis ; *Evaluation Studies as Topic ; Goals ; New Zealand ; Policy Making ; Public Sector/economics ; Research/*economics ; *Research Support as Topic

2016-05-19

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

2014-12-04

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Animals ; Carcinoma, Hepatocellular/*etiology/therapy ; Fatty Liver/*complications/pathology ; Humans ; Inflammation ; Liver Cirrhosis/etiology ; Liver Neoplasms/*etiology/therapy

2014-10-25

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Animals ; Caenorhabditis elegans/*metabolism ; *Longevity ; Male ; Mitochondria/*metabolism ; Superoxides/*metabolism

1525-1314

Blackwell Publishing Journal Backfiles 1879-2005

Geosciences

Abstract Natural, pure CO2 inclusions in quartz and olivine (c. Fo90) were exposed to controlled fH2 conditions at T= 718–728°C and Ptotal= 2 kbar; their compositions were monitored (before and after exposures) by microsampling Raman spectroscopy (MRS) and microthermometry. In both minerals exposed at the graphite–methane buffer (fH2= 73 bar), fluid speciations record the diffusion of hydrogen into the inclusions. In quartz, room-temperature products in euhedral isolated (EI type) inclusions are carbonic phases with molar compositions of c. CO2(60) + CH4(40) plus graphite (Gr) and H2O, whereas anhedral inclusions along secondary fractures (AS type) are Gr-free and contain H2O plus carbonic phases with compositions in the range c. CO2(60) + CH4(40) to CO2(10) + CH4(90). EI type inclusions in olivine evolved to c. CO2(90–95) + CH4(5–10) without Gr, whereas AS type inclusions have a range of compositions from CO2(90) + CH4(10) ± Gr to CH4(50) + H2(50) ± Gr; neither H2O nor any hydrous species was detected by optical microscopy or MRS in the olivine-hosted products. Differences in composition between and among the texturally distinct populations of inclusions in both minerals probably arise from variations in initial fluid densities, as all inclusions apparently equilibrated with the ambient fH2. These relations suggest that compositional variability among inclusions in a given natural sample does not require the entrapment of multiple generations of fluids. In addition, the absence of H2O in the olivine-hosted inclusions would require the extraction of oxygen from the fluids, in which case re-equilibration mechanisms may be dependent on the composition and structure of the host mineral.Many of the same samples were re-exposed to identical P–T conditions using Ar as the pressure medium, yielding ambient fH2= 0.06 bar. In most inclusions, the carbonic fluids returned to pure CO2 and graphite persisted in the products. Reversal of the mechanisms from the prior exposure at fH2= 73 bar did not occur in any inclusions but the AS types in olivine, in which minor CO2 was produced at the expense of CH4 and/or graphite. The observed non-reversibility of previous mechanisms may be attributed to: (1) slower fluid–solid reactions compared to reactions in the homogeneous fluid phase; (2) depressed activities of graphite due to poor ordering; and/or (3) low ambient fO2 at the conditions of the second run.

Electronic Resource

Online

2023

Neue Technologien ; Lernsoftware ; Video ; Fernstudium ; Fernunterricht ; E-Learning

International journal of lifelong education, Bd. 42 (2023) H. 3, S. 283-297, 1464-519X

English

2018-01-12

American Chemical Society (ACS)

0002-7863

1520-5126

Chemistry and Pharmacology

2018-03-28

The American Society for Microbiology (ASM)

0066-4804

1098-6596

Biology

Medicine

1089-7623

AIP Digital Archive

Physics

Electrical Engineering, Measurement and Control Technology

Many circuit functions can now be realized using digital rather than analog techniques. The application of digital signal processing (DSP) technology for the implementation of the feedback control loop of a scanning tunneling microscope is discussed. A system that utilizes a commercially available PC AT-compatible plug-in card based on the Texas Instruments TMS320 series of digital processing chips to implement a loop controller of the proportional-integral-differential type is described. The advantages afforded by DSP in comparison to analog systems include greater flexibility in the choice of the signal processing algorithm and greater ease of control of loop parameters by the host computer.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

Ballistic electron emission microscopy (BEEM) is used to measure hot-electron transport across magnetic metal multilayers. Room temperature measurements in air have been carried out on Au/M/Si(100), Au/M/Au/Si(100), and Au/M/PtSi/Si diodes, that were sputter deposited at 175 or 300 K, where M is Co, Fe, Ni, Cu, or Ni81Fe19. Plots of log BEEM current versus M thickness are linear giving hot-electron (1.5 eV) attenuation lengths (ALs), for Au/M/Si diodes (M=Co, Fe, Ni81Fe19, and Ni) of 0.3, 0.5, 0.8, and 1.3 nm, respectively (with typical standard uncertainties of ±10%). Magnetic metal sandwich diodes, (Au/M/Au/Si) show larger ALs, 0.8 and 2.1 nm, for M=Co and Ni81Fe19, respectively. PtSi interlayers improve the surface roughness but have little effect on the AL while low temperature depositions increase the AL. We presume that the increases in the AL are due to better microstructure, less silicide reaction, or to changes in elastic scattering at interfaces. © 2000 American Institute of Physics.

Electronic Resource

1365-2214

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Psychology

Previous work has demonstrated both that there are substantial individual differences in the rate of physiological development, and that infants with risk factors for Sudden Infant Death Syndrome (SIDS) develop more slowly, suggesting that their increased vulnerability may be due to delayed neuronal development associated with compromised development in fetal or early neonatal life. This project aims to test the hypothesis that individual differences in the rate of physiological development of infants correlate with measurable differences in the rate of brain development as assessed by magnetic resonance imaging (MRI).Sixty infants were recruited to this study in three different groups that are known to have differing rates of physiological development. MRI was performed successfully in 49 cases at 6 weeks of age without sedation. Forty-one of these cases had full follow-up (15 normal; 19 IUGR; 11 ‘high risk’). Postnatal physiological development was assessed by measuring age-related deep body temperature patterns during sleep. Neuronal development was assessed by subjective analysis of MRI images and objective measurements relating to myelination using T1 and diffusion weighted (23 cases) MRI images.As expected the normal group acquired the adult temperature pattern earlier, but this was not statistically significant. All MRI scan appearances were within normal limits. Ranking cases subjectively in order of maturity revealed no significant pattern. The normal group had a significantly higher myelination score than the IUGR and ‘high risk’ groups (P = 0.001). This trend was also shown by the diffusion weighted myelination score but did not reach statistical significance. No significant differences were seen in both the subjective and objective MRI measurements and development of nocturnal temperature patterns.The results suggest there may be differences in neurodevelopment between the different groups at 6 weeks of age but these are not linked to late development of temperature patterns. It is therefore unlikely that this related to a global delay in maturation.

Electronic Resource

1471-0528

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

An epidural technique based on a fractionated injection through a Tuohy needle of 20 ml over 10 minutes, was investigated in 40 mothers who underwent elective Caesarean section. Mothers were randomised to receive either 0.5% bupivacaine plain or 0.5% bupivacaine with adrenaline 1:200 000. After a 2-ml test dose, the remaining 18 ml was injected over 5 minutes. The use of adrenaline did not significantly alter the onset or duration, but improved the efficacy of the epidural block. Mean time to onset of adequate surgical anaesthesia was 20 minutes. Only 10 patients required more than the initial 100 mg of bupivacaine. Epidural anaesthesia was supplemented in eight patients with nitrous oxide and/or intravenous opioids.

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

To investigate current concerns that potent opioid drugs, such as fentanyl, used for labour regional analgesia may affect neonatal status, maternal and umbilical plasma concentrations of fentanyl and bupivacaine at delivery were measured in 40 nulliparous patients receiving low-dose combined spinal epidural analgesia. Neonatal assessments included Apgar scores, umbilical blood gases and neurobehavioural tests. All maternal and umbilical venous plasma concentrations were low. Maternal and umbilical vein total fentanyl concentrations increased with increasing doses of epidural fentanyl (r = 0.46 and 0.30, respectively, p 〈 0.01). There were no significant differences between maternal and umbilical venous plasma total or free concentrations of fentanyl. Mean umbilical vein/maternal fentanyl ratios were 1.12 for total drug and 1.20 for free drug and values were unrelated to the last epidural bolus to delivery interval (r = 0.12, p = 0.49). There were no correlations between Apgar scores, umbilical blood gases or neurobehavioural scores and umbilical venous concentrations of either fentanyl or bupivacaine. The dose of fentanyl used for ambulatory combined spinal epidural analgesia would appear to have a negligible effect on neonatal condition.

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Two hundred and twenty-nine nulliparous women who requested regional analgesia during labour were given a combined spinal–epidural block. They were randomly allocated to stay in bed or spend at least 20 min of every hour out of bed. There was no significant difference in duration of labour, analgesia requirements, mode of delivery or condition of the baby between the groups. Ambulation appeared to be safe for the mother and baby. Maternal satisfaction with the low-dose combined spinal–epidural was high in both groups.

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

A 120 mm, 27-gauge needle has recently been introduced for subarachnoid anaesthesia when using a single-space, combined spinal-extradural technique. The flow characteristics of this needle were compared with those of a 120 mm, 26-gauge needle using a pressure monitor infusion pump. Surprisingly, the resistance to fluid flow of the 26-gauge needle was twice that of the 27-gauge needle. The results of this experiment were confirmed by the findings of a clinical study undertaken in 100 obstetric patients who required regional anaesthesia. The time taken from dural puncture to appearance of cerebrospinal fluid at the hub of the needle was on average three times greater with the 26-gauge needle.

Electronic Resource