Search Results - (Author, Cooperation:B. K. Martin)
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1Latest Papers from Table of Contents or Articles in PressA. Adey ; J. N. Burton ; J. O. Kitzman ; J. B. Hiatt ; A. P. Lewis ; B. K. Martin ; R. Qiu ; C. Lee ; J. Shendure
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-08-09Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aneuploidy ; DNA Copy Number Variations ; *Epigenomics ; Female ; Genes, myc/genetics ; Genome, Human/*genetics ; Haplotypes ; HeLa Cells ; Human papillomavirus 18/genetics/physiology ; Humans ; Molecular Sequence Data ; Mutation ; Sequence Analysis, DNA ; Transcriptional Activation/genetics ; Uterine Cervical Neoplasms/genetics/pathology/virologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressB. J. O'Roak ; L. Vives ; W. Fu ; J. D. Egertson ; I. B. Stanaway ; I. G. Phelps ; G. Carvill ; A. Kumar ; C. Lee ; K. Ankenman ; J. Munson ; J. B. Hiatt ; E. H. Turner ; R. Levy ; D. R. O'Day ; N. Krumm ; B. P. Coe ; B. K. Martin ; E. Borenstein ; D. A. Nickerson ; H. C. Mefford ; D. Doherty ; J. M. Akey ; R. Bernier ; E. E. Eichler ; J. Shendure
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-11-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cephalometry ; Child ; Child Development Disorders, Pervasive/*genetics ; Child, Preschool ; Chromatin Assembly and Disassembly ; Cohort Studies ; DNA Probes ; DNA-Binding Proteins/genetics ; Exome ; Female ; *Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Male ; Megalencephaly/genetics ; Microcephaly/genetics ; *Mutation ; Nuclear Proteins/genetics ; PTEN Phosphohydrolase/genetics ; Protein-Serine-Threonine Kinases/genetics ; Protein-Tyrosine Kinases/genetics ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, N-Methyl-D-Aspartate/genetics ; Repressor Proteins/genetics ; Sequence Analysis, DNA/*methods ; T-Box Domain Proteins/genetics ; Transcription Factors/genetics ; beta Catenin/genetics/metabolismPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 0025-8385Topics: Linguistics and Literary StudiesURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0025-8385Topics: Linguistics and Literary StudiesURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] There are many well known methods of interpreting data on the excretion of drugs and their metabolites. The author suggests another, and claims that it may be an improvement in some ...Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] A3 investigation of the rate at which the unchanged drug or its metabolites appear in the urine after drug administration is an established technique in pharmaco-kinetic investigations. This method was used by Bray, Thorpe and White1 in their investigations of the kinetics of drug metabolism in ...Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] THE theoretical and practical aspects of the interaction of drugs with plasma proteins have been considered by Goldstein1, Edsall and Wyman2 and others3-6, and it is generally accepted7 that the 'protein-binding' of a drug in this manner can modify its distribution in the body and therefore ...Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] THE classical method of determining the rate of elimination of a drug from the body is to examine the decline of the plasma concentration of the drug with respect to time. I have pointed out1 that this method is only valid when throughout the period of investigation the plasma contains a constant ...Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] An examination of the urinary excretion (Fig. 1) shows that both aspirin B.P. and aloxiprin give rise to excretion-rates which are almost identical at their respective maxima, although in the case of aloxiprin the maximum is reached later. It is suggested that this delay in the achievement of a ...Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The consequence of this theory does not appear to have been considered in relation to the gastric mucosal cells when an acidic substance is absorbed from the stomach. Theoretical considerations suggest that after the oral administration of certain acidic drugs, appreciable quantities of drug anion ...Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] THE relationship of the rate of decline of a drug in the plasma to the rate of excretion of unchanged drug in the urine has been established in respect of a number of drugs, for example, sulphaethylthiadiazole1 and tetra-cycline2. A similar study of the rate of excretion of metabolites when a drug ...Type of Medium: Electronic ResourceURL: