Search Results - (Author, Cooperation:B. Jabri)
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1A. Sivan ; L. Corrales ; N. Hubert ; J. B. Williams ; K. Aquino-Michaels ; Z. M. Earley ; F. W. Benyamin ; Y. M. Lei ; B. Jabri ; M. L. Alegre ; E. B. Chang ; T. F. Gajewski
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-11-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antibodies, Monoclonal/*therapeutic use ; Antigens, CD274/*immunology ; Bifidobacterium/genetics/*immunology ; CD8-Positive T-Lymphocytes/immunology ; Dendritic Cells/immunology ; Fecal Microbiota Transplantation ; Gastrointestinal Microbiome/*immunology ; Gene Expression Regulation ; Humans ; Immunity/genetics ; Immunotherapy/methods ; Lymphocyte Activation ; Melanoma/*immunology/*therapy ; Mice ; Mice, Inbred C57BL ; RNA, Ribosomal, 16S/genetics ; Skin Neoplasms/*immunology/*therapy ; Symbiosis ; T-Lymphocytes/immunology ; Tumor Microenvironment/immunologyPublished by: -
2Staff View
Publication Date: 2015-11-14Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Capillary Permeability/*immunology ; Humans ; Intestines/*immunology/*microbiology ; Microbiota/*immunology ; Salmonella Infections/*immunology ; Salmonella typhimurium/*immunologyPublished by: -
3S. Devkota ; Y. Wang ; M. W. Musch ; V. Leone ; H. Fehlner-Peach ; A. Nadimpalli ; D. A. Antonopoulos ; B. Jabri ; E. B. Chang
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bile Acids and Salts/metabolism ; Bilophila/*drug effects/growth & development ; Colitis/*chemically induced/immunology/*microbiology/pathology ; Diet, Fat-Restricted ; Dietary Fats/*pharmacology ; Inflammation/chemically induced/immunology/microbiology ; Inflammatory Bowel Diseases/chemically induced/microbiology/pathology ; Interleukin-10/*deficiency/genetics ; Metagenome/*drug effects ; Mice ; Mice, Inbred C57BL ; Milk/chemistry ; Molecular Sequence Data ; Safflower Oil/pharmacology ; Sulfites/metabolism ; Taurine/metabolism ; Taurocholic Acid/*metabolism/pharmacology ; Th1 Cells/drug effects/immunologyPublished by: -
4J. L. Round ; S. M. Lee ; J. Li ; G. Tran ; B. Jabri ; T. A. Chatila ; S. K. Mazmanian
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-04-23Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacteroides fragilis/*growth & development/*immunology ; Colon/immunology/microbiology ; Germ-Free Life ; Homeostasis ; Humans ; *Immune Tolerance ; Immunity, Mucosal ; Interleukin-10/metabolism ; Intestinal Mucosa/*immunology/*microbiology ; Metagenome ; Mice ; Mice, Inbred C57BL ; Models, Biological ; Polysaccharides, Bacterial/immunology/*metabolism ; Signal Transduction ; Specific Pathogen-Free Organisms ; Symbiosis ; T-Lymphocytes, Regulatory/immunology ; Th17 Cells/immunology ; Toll-Like Receptor 2/immunology/*metabolismPublished by: -
5R. W. DePaolo ; V. Abadie ; F. Tang ; H. Fehlner-Peach ; J. A. Hall ; W. Wang ; E. V. Marietta ; D. D. Kasarda ; T. A. Waldmann ; J. A. Murray ; C. Semrad ; S. S. Kupfer ; Y. Belkaid ; S. Guandalini ; B. Jabri
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adjuvants, Immunologic/*pharmacology ; Administration, Oral ; Adolescent ; Adult ; Animals ; Celiac Disease/chemically induced/etiology/*immunology ; Cells, Cultured ; Child ; Child, Preschool ; Coculture Techniques ; Dendritic Cells/drug effects/enzymology/immunology/metabolism ; Diet ; Forkhead Transcription Factors/metabolism ; Gliadin/administration & dosage/immunology ; Glutens/administration & dosage/*immunology ; HLA-DQ Antigens/genetics/immunology ; Humans ; Immune Tolerance/drug effects ; Inflammation/immunology ; Interleukin-12/biosynthesis/immunology/secretion ; Interleukin-15/genetics/*immunology ; Interleukin-23/immunology/secretion ; Intestinal Mucosa/cytology/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Middle Aged ; Mitogen-Activated Protein Kinase 8/metabolism ; Phosphorylation/drug effects ; Receptors, Interleukin-12/deficiency ; T-Lymphocytes, Regulatory/cytology/drug effects/immunology/metabolism ; Tretinoin/immunology/*pharmacology ; Young AdultPublished by: -
6Hu, M. D., Ethridge, A. D., Lipstein, R., Kumar, S., Wang, Y., Jabri, B., Turner, J. R., Edelblum, K. L.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-07-10Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
7Patey-Mariaud de Serre, N ; Cellier, C ; Jabri, B ; Delabesse, E ; Verkarre, V ; Roche, B ; Lavergne, A ; Brière, J ; Mauvieux, L ; Leborgne, M ; Barbier, J P ; Modigliani, R ; Matuchansky, C ; Macintyre, E ; Cerf-Bensussan, N ; Brousse, N
Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
Published 2000Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We recently showed that refractory sprue is distinct from coeliac disease, the former being characterized by abnormal intraepithelial T-lymphocytes expressing a cytoplasmic CD3 chain (CD3c), lacking CD3 and CD8 surface expression, and showing TCRγ gene rearrangements. To take advantage of the abnormal phenotype of CD3c + CD8 − intraepithelial lymphocytes (IEL) in refractory sprue we developed a simple method to distinguish coeliac disease from refractory sprue.〈section xml:id="abs1-2"〉〈title type="main"〉Methods and resultsComparative immunohistochemical studies using anti-CD3 and anti-CD8 antibodies were applied on paraffin-embedded and frozen biopsy specimens in refractory sprue (n = 6), coeliac disease (n = 10), healthy controls (n = 5) and suspected refractory sprue (n = 6). Comparable results were obtained on fixed and frozen biopsy specimens. In four of the six patients with suspected refractory sprue, abnormal CD3c + CD8 − IEL and TCRγ gene rearrangements were found, as in refractory sprue; the remaining two patients had normal (CD3 + CD8 +) IEL and no TCRγ gene rearrangements. Both patients had coeliac disease, as one failed to comply with a gluten-free diet, while the other was a slow responder.〈section xml:id="abs1-3"〉〈title type="main"〉ConclusionThis simplified immunostaining method using anti-CD3 and anti-CD8 antibodies on paraffin sections can distinguish active coeliac disease from refractory sprue and should prove useful in clinical practice.Type of Medium: Electronic ResourceURL: