Search Results - (Author, Cooperation:B. Jabri)

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  1. 1
    A. Sivan ; L. Corrales ; N. Hubert ; J. B. Williams ; K. Aquino-Michaels ; Z. M. Earley ; F. W. Benyamin ; Y. M. Lei ; B. Jabri ; M. L. Alegre ; E. B. Chang ; T. F. Gajewski
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-11-07
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Antibodies, Monoclonal/*therapeutic use ; Antigens, CD274/*immunology ; Bifidobacterium/genetics/*immunology ; CD8-Positive T-Lymphocytes/immunology ; Dendritic Cells/immunology ; Fecal Microbiota Transplantation ; Gastrointestinal Microbiome/*immunology ; Gene Expression Regulation ; Humans ; Immunity/genetics ; Immunotherapy/methods ; Lymphocyte Activation ; Melanoma/*immunology/*therapy ; Mice ; Mice, Inbred C57BL ; RNA, Ribosomal, 16S/genetics ; Skin Neoplasms/*immunology/*therapy ; Symbiosis ; T-Lymphocytes/immunology ; Tumor Microenvironment/immunology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    R. Bouziat ; B. Jabri
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-11-14
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Capillary Permeability/*immunology ; Humans ; Intestines/*immunology/*microbiology ; Microbiota/*immunology ; Salmonella Infections/*immunology ; Salmonella typhimurium/*immunology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    S. Devkota ; Y. Wang ; M. W. Musch ; V. Leone ; H. Fehlner-Peach ; A. Nadimpalli ; D. A. Antonopoulos ; B. Jabri ; E. B. Chang
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-06-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bile Acids and Salts/metabolism ; Bilophila/*drug effects/growth & development ; Colitis/*chemically induced/immunology/*microbiology/pathology ; Diet, Fat-Restricted ; Dietary Fats/*pharmacology ; Inflammation/chemically induced/immunology/microbiology ; Inflammatory Bowel Diseases/chemically induced/microbiology/pathology ; Interleukin-10/*deficiency/genetics ; Metagenome/*drug effects ; Mice ; Mice, Inbred C57BL ; Milk/chemistry ; Molecular Sequence Data ; Safflower Oil/pharmacology ; Sulfites/metabolism ; Taurine/metabolism ; Taurocholic Acid/*metabolism/pharmacology ; Th1 Cells/drug effects/immunology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    J. L. Round ; S. M. Lee ; J. Li ; G. Tran ; B. Jabri ; T. A. Chatila ; S. K. Mazmanian
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-04-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bacteroides fragilis/*growth & development/*immunology ; Colon/immunology/microbiology ; Germ-Free Life ; Homeostasis ; Humans ; *Immune Tolerance ; Immunity, Mucosal ; Interleukin-10/metabolism ; Intestinal Mucosa/*immunology/*microbiology ; Metagenome ; Mice ; Mice, Inbred C57BL ; Models, Biological ; Polysaccharides, Bacterial/immunology/*metabolism ; Signal Transduction ; Specific Pathogen-Free Organisms ; Symbiosis ; T-Lymphocytes, Regulatory/immunology ; Th17 Cells/immunology ; Toll-Like Receptor 2/immunology/*metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2011-02-11
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adjuvants, Immunologic/*pharmacology ; Administration, Oral ; Adolescent ; Adult ; Animals ; Celiac Disease/chemically induced/etiology/*immunology ; Cells, Cultured ; Child ; Child, Preschool ; Coculture Techniques ; Dendritic Cells/drug effects/enzymology/immunology/metabolism ; Diet ; Forkhead Transcription Factors/metabolism ; Gliadin/administration & dosage/immunology ; Glutens/administration & dosage/*immunology ; HLA-DQ Antigens/genetics/immunology ; Humans ; Immune Tolerance/drug effects ; Inflammation/immunology ; Interleukin-12/biosynthesis/immunology/secretion ; Interleukin-15/genetics/*immunology ; Interleukin-23/immunology/secretion ; Intestinal Mucosa/cytology/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Middle Aged ; Mitogen-Activated Protein Kinase 8/metabolism ; Phosphorylation/drug effects ; Receptors, Interleukin-12/deficiency ; T-Lymphocytes, Regulatory/cytology/drug effects/immunology/metabolism ; Tretinoin/immunology/*pharmacology ; Young Adult
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2018-07-10
    Publisher:
    The American Association of Immunologists (AAI)
    Print ISSN:
    0022-1767
    Electronic ISSN:
    1550-6606
    Topics:
    Medicine
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    We recently showed that refractory sprue is distinct from coeliac disease, the former being characterized by abnormal intraepithelial T-lymphocytes expressing a cytoplasmic CD3 chain (CD3c), lacking CD3 and CD8 surface expression, and showing TCRγ gene rearrangements. To take advantage of the abnormal phenotype of CD3c + CD8 − intraepithelial lymphocytes (IEL) in refractory sprue we developed a simple method to distinguish coeliac disease from refractory sprue.〈section xml:id="abs1-2"〉〈title type="main"〉Methods and resultsComparative immunohistochemical studies using anti-CD3 and anti-CD8 antibodies were applied on paraffin-embedded and frozen biopsy specimens in refractory sprue (n = 6), coeliac disease (n = 10), healthy controls (n = 5) and suspected refractory sprue (n = 6). Comparable results were obtained on fixed and frozen biopsy specimens. In four of the six patients with suspected refractory sprue, abnormal CD3c + CD8 − IEL and TCRγ gene rearrangements were found, as in refractory sprue; the remaining two patients had normal (CD3 + CD8 +) IEL and no TCRγ gene rearrangements. Both patients had coeliac disease, as one failed to comply with a gluten-free diet, while the other was a slow responder.〈section xml:id="abs1-3"〉〈title type="main"〉ConclusionThis simplified immunostaining method using anti-CD3 and anti-CD8 antibodies on paraffin sections can distinguish active coeliac disease from refractory sprue and should prove useful in clinical practice.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses