Search Results - (Author, Cooperation:B. H. Chong)

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  1. 1
    G. J. Maghzal ; S. Winter ; B. Wurzer ; B. H. Chong ; R. Holmdahl ; R. Stocker
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-10-25
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Granulomatous Disease, Chronic/*metabolism/*pathology ; Inflammation/*metabolism ; Kynurenine/*metabolism ; Tryptophan/*metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Chong, B. H. ; Berndt, M. C.
    Springer
    Published 1989
    Staff View
    ISSN:
    1432-0584
    Keywords:
    Thrombocytopenia ; Heparin anticoagulant therapy ; Complication
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Thrombocytopenia is a frequent and sometimes insidious complication of anticoagulant therapy with heparin. Two types of heparin-induced thrombocytopenia with a distinct aetiology have been recognized. Type I is characterized by a mild thrombocytopenia of early onset which requires careful monitoring but usually not the cessation of heparin therapy. The mild thrombocytopenia is probably due to the mild pro-aggregatory properties of heparin and can be more severe in the presence of other predisposing factors, e.g. sepsis. Type II heparin-induced thrombocytopenia is more severe and usually occurs after a period of 7–10 days. Heparin therapy should be ceased immediately and other anticoagulant therapy initiated. The thrombocytopenia is believed to be due to the development of a heparin-dependent antibody that causes platelet aggregation and release. The precise mechanism of heparin-dependent antibody-platelet interaction is still not entirely clear but probably involves the binding of an antibody-heparin immune complex to the platelet Fc receptor.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00320647

    Articles: DFG German National Licenses
  3. 3
    Chong, B. H.
    Springer
    Published 1991
    Staff View
    ISSN:
    1432-1238
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01720689

    Articles: DFG German National Licenses