Search Results - (Author, Cooperation:A. Ziegler)

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  1. 1
    Staff View
    Publication Date:
    2012-08-17
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    ABO Blood-Group System ; Anemia, Sickle Cell ; Case-Control Studies ; Chromosomes, Human, Pair 1/genetics ; Chromosomes, Human, Pair 16/genetics ; Disease Resistance/*genetics ; Genetic Loci/*genetics ; *Genome-Wide Association Study ; Ghana ; Humans ; Malaria, Falciparum/*genetics/parasitology/pathology ; Membrane Proteins/genetics ; Plasma Membrane Calcium-Transporting ATPases/genetics ; Polymorphism, Single Nucleotide/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    J. Yang ; R. J. Loos ; J. E. Powell ; S. E. Medland ; E. K. Speliotes ; D. I. Chasman ; L. M. Rose ; G. Thorleifsson ; V. Steinthorsdottir ; R. Magi ; L. Waite ; A. V. Smith ; L. M. Yerges-Armstrong ; K. L. Monda ; D. Hadley ; A. Mahajan ; G. Li ; K. Kapur ; V. Vitart ; J. E. Huffman ; S. R. Wang ; C. Palmer ; T. Esko ; K. Fischer ; J. H. Zhao ; A. Demirkan ; A. Isaacs ; M. F. Feitosa ; J. Luan ; N. L. Heard-Costa ; C. White ; A. U. Jackson ; M. Preuss ; A. Ziegler ; J. Eriksson ; Z. Kutalik ; F. Frau ; I. M. Nolte ; J. V. Van Vliet-Ostaptchouk ; J. J. Hottenga ; K. B. Jacobs ; N. Verweij ; A. Goel ; C. Medina-Gomez ; K. Estrada ; J. L. Bragg-Gresham ; S. Sanna ; C. Sidore ; J. Tyrer ; A. Teumer ; I. Prokopenko ; M. Mangino ; C. M. Lindgren ; T. L. Assimes ; A. R. Shuldiner ; J. Hui ; J. P. Beilby ; W. L. McArdle ; P. Hall ; T. Haritunians ; L. Zgaga ; I. Kolcic ; O. Polasek ; T. Zemunik ; B. A. Oostra ; M. J. Junttila ; H. Gronberg ; S. Schreiber ; A. Peters ; A. A. Hicks ; J. Stephens ; N. S. Foad ; J. Laitinen ; A. Pouta ; M. Kaakinen ; G. Willemsen ; J. M. Vink ; S. H. Wild ; G. Navis ; F. W. Asselbergs ; G. Homuth ; U. John ; C. Iribarren ; T. Harris ; L. Launer ; V. Gudnason ; J. R. O'Connell ; E. Boerwinkle ; G. Cadby ; L. J. Palmer ; A. L. James ; A. W. Musk ; E. Ingelsson ; B. M. Psaty ; J. S. Beckmann ; G. Waeber ; P. Vollenweider ; C. Hayward ; A. F. Wright ; I. Rudan ; L. C. Groop ; A. Metspalu ; K. T. Khaw ; C. M. van Duijn ; I. B. Borecki ; M. A. Province ; N. J. Wareham ; J. C. Tardif ; H. V. Huikuri ; L. A. Cupples ; L. D. Atwood ; C. S. Fox ; M. Boehnke ; F. S. Collins ; K. L. Mohlke ; J. Erdmann ; H. Schunkert ; C. Hengstenberg ; K. Stark ; M. Lorentzon ; C. Ohlsson ; D. Cusi ; J. A. Staessen ; M. M. Van der Klauw ; P. P. Pramstaller ; S. Kathiresan ; J. D. Jolley ; S. Ripatti ; M. R. Jarvelin ; E. J. de Geus ; D. I. Boomsma ; B. Penninx ; J. F. Wilson ; H. Campbell ; S. J. Chanock ; P. van der Harst ; A. Hamsten ; H. Watkins ; A. Hofman ; J. C. Witteman ; M. C. Zillikens ; A. G. Uitterlinden ; F. Rivadeneira ; L. A. Kiemeney ; S. H. Vermeulen ; G. R. Abecasis ; D. Schlessinger ; S. Schipf ; M. Stumvoll ; A. Tonjes ; T. D. Spector ; K. E. North ; G. Lettre ; M. I. McCarthy ; S. I. Berndt ; A. C. Heath ; P. A. Madden ; D. R. Nyholt ; G. W. Montgomery ; N. G. Martin ; B. McKnight ; D. P. Strachan ; W. G. Hill ; H. Snieder ; P. M. Ridker ; U. Thorsteinsdottir ; K. Stefansson ; T. M. Frayling ; J. N. Hirschhorn ; M. E. Goddard ; P. M. Visscher
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-09-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Body Height/genetics ; *Body Mass Index ; Co-Repressor Proteins ; Female ; *Genetic Variation ; Genome-Wide Association Study ; Humans ; Male ; Nerve Tissue Proteins/genetics ; *Phenotype ; Polymorphism, Single Nucleotide ; Proteins/*genetics ; Repressor Proteins/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Type of Medium:
    av_media
    Publication Date:
    2003
    Keywords:
    Biophysik ; Lebewesen ; Antrieb (Tech) ; Newtonsche Mechanik ; Physik
    In:
    Didaktik der Physik ... CD zur Frühjahrstagung des Fachverbandes Didaktik der Physik in der Deutschen Physikalischen Gesellschaft, Bd. Physikertagung 2003 Augsburg (2003), 3-936427-71-2
    Language:
    German

    FIS Bildung Literaturdatenbank
  4. 4
    Staff View
    Type of Medium:
    article
    Publication Date:
    1998
    Keywords:
    Pädagogische Theorie ; Leistungsmotivation
    In:
    Psychologie in Erziehung und Unterricht, Bd. 45 (1998) H. 3, S. 161-167, 0342-183X
    Language:
    German

    FIS Bildung Literaturdatenbank
  5. 5
    Staff View
    Type of Medium:
    article
    Publication Date:
    1996
    Keywords:
    Didaktik ; Physikunterricht ; Quantenmechanik ; Unschärferelation
    In:
    Vorträge / Physikertagung, Deutsche Physikalische Gesellschaft, Fachausschuß Didaktik der Physik, Bd. Tagung 1995 (1996) S. 272-275, 1430-564X
    Language:
    German

    FIS Bildung Literaturdatenbank
  6. 6
    Staff View
    Type of Medium:
    article
    Publication Date:
    1994
    Keywords:
    Physikunterricht ; Quantenmechanik ; Quantenphysik ; Quantentheorie ; Unschärferelation
    In:
    Vorträge / Physikertagung, Deutsche Physikalische Gesellschaft, Fachausschuß Didaktik der Physik, Bd. Tagung 1993 (1994) S. 571-576, 3-923835-14-0
    Language:
    German

    FIS Bildung Literaturdatenbank
  7. 7
    Ziegler, A. [Verfasser]

    Published 2000
    Staff View
    Type of Medium:
    av_media
    Publication Date:
    2000
    Keywords:
    Fehlvorstellung ; Mechanik ; Physik ; Physikgeschichte
    In:
    CD zur Frühjahrstagung des Fachverbandes Didaktik der Physik in der Deutschen Physikalischen Gesellschaft, Bd. Physikertagung 2000 Dresden (2000), 3-931253-71-6
    Language:
    German

    FIS Bildung Literaturdatenbank
  8. 8
    Ziegler, A. [Verfasser]

    Published 2001
    Staff View
    Type of Medium:
    av_media
    Publication Date:
    2001
    Keywords:
    Elektrische Ladung ; Elektrisches Feld ; Feld (Phys) ; Magnetisches Feld ; Magnetismus ; Compactdisc
    In:
    CD zur Frühjahrstagung des Fachverbandes Didaktik der Physik in der Deutschen Physikalischen Gesellschaft, Bd. Physikertagung 2001 Bremen (2001), 3-931253-87-2
    Language:
    German

    FIS Bildung Literaturdatenbank
  9. 9
    Staff View
    Type of Medium:
    Online
    Publication Date:
    2014
    Keywords:
    Kompetenz ; Förderung ; Schule ; Didaktik ; Wald ; Wasser ; Wiese ; Chemie ; Naturwissenschaften ; Kooperation
    In:
    Bernholt, Sascha (Hrsg.), Naturwissenschaftliche Bildung zwischen Science- und Fachunterricht., Kiel: IPN (2014), S. 615-617, 978-3-89088-361-8
    Language:
    German

    FIS Bildung Literaturdatenbank
  10. 10
    Ziegler, A. [Verfasser]

    Published 2002
    Staff View
    Type of Medium:
    av_media
    Publication Date:
    2002
    Keywords:
    Physik ; Physikunterricht ; Quantenphysik ; Interpretation
    In:
    Didaktik der Physik ... CD zur Frühjahrstagung des Fachverbandes Didaktik der Physik in der Deutschen Physikalischen Gesellschaft, Bd. Physikertagung 2002 Leipzig (2002), 3-936427-11-9
    Language:
    German

    FIS Bildung Literaturdatenbank
  11. 11
    Staff View
    Publication Date:
    2018-10-09
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    0031-9007
    Electronic ISSN:
    1079-7114
    Topics:
    Physics
    Keywords:
    Plasma and Beam Physics
    Published by:
    http://www.aps.org/

    Latest Papers from Table of Contents or Articles in Press
  12. 12
    Rémy, C. ; Arús, C. ; Ziegler, A. ; Lai, E. Sam ; Moreno, A. ; Fur, Y. Le ; Décorps, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1994
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: An in vivo study of intracerebral rat glioma using proton-localized NMR spectroscopy showed important modifications of the spectra in the tumor as compared with the contralateral brain. To carry out the assignment of the resonances of the glioma spectra, tumoral and normal rat brain tissues were studied in vivo, ex vivo, and in vitro by one-dimensional and two-dimensional proton spectroscopy. N-Acetylaspartate was found at an extremely low level in the glioma. The change of peak ratio total creatine/3.2 ppm peak was found to be due to a simultaneous decrease of the total creatine content and an increase of the 3.2 ppm peak. The 3.2 ppm resonance in the glioma spectra has been shown to originate from choline, phosphocholine, glycerophosphocholine, taurine, inositol, and phosphoethanolamine. The increase of the 3.2 ppm peak in the glioma was found to result from the increase of taurine and phosphoethanolamine contents. The peak in the 1.3 ppm region of the glioma spectra was due to both lactate and mobile fatty acids. Moreover, two-dimensional spectroscopy of excised tissues and extracts showed the presence of hypotaurine only in the tumor.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1471-4159.1994.62010166.x

    Articles: DFG German National Licenses
  13. 13
    ZIEGLER, A.

    Oxford, UK : Blackwell Publishing
    Published 1962
    Staff View
    ISSN:
    1468-5922
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1465-5922.1962.00141.x

    Articles: DFG German National Licenses
  14. 14
    Dhar, S. ; Ziegler, A. ; Kanhere@f @f, D. G. ; Callaway, J.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1985
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Ab initio self-consistent spin polarized calculations have been performed for the electronic structure of the heteronuclear diatomic molecules LiH, CO, and NO; using local spin density functional theory. The Kohn–Sham functions have been expanded in terms of a basis set of Gaussian orbitals. All the one and two electron integrals are calculated exactly. The matrix elements of the exchange correlation potential are computed numerically using a two dimensional doubling grid developed for this purpose. The total energy, the binding energy, the equilibrium distance, the vibrational frequency, and the dipole moment are reported and compared with experimental results and with other calculations. The agreement of our results with experimental values is very good in all cases.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.448514

    Articles: DFG German National Licenses
  15. 15
    Berghöfer, B. ; Frommer, T. ; König, I. R. ; Ziegler, A. ; Chakraborty, T. ; Bein, G. ; Hackstein, H.

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background Toll-like receptor 9 (TLR9) is a pattern-recognition receptor that detects unmethylated CpG motifs prevalent in bacterial and viral DNA. TLR9 stimulation is a key event after bacterial infection, triggering innate immunity and T-helper type 1 skewed adaptive immunity. Synthetic CpG-oligodeoxynucleotides (CpG-ODNs) represent a promising and novel class of immune adjuvants for allergy treatment, vaccination, and cancer therapy. However, common functional TLR9 gene variants could interfere with the clinical utilization of CpG-ODN in immunotherapy. Recently, a possible association of TLR9 polymorphism C-1237T with asthma has been reported.Objective The aim of the present study was to investigate whether TLR9 polymorphisms or haplotypes have functional relevance and are associated with atopy.Methods We genotyped five common TLR9 single-nucleotide polymorphisms (SNPs) in promoter, exon, and intron regions of the gene in 527 healthy blood donors, and estimated four common haplotypes. The total IgE and specific IgE levels against the most common aeroallergens were measured (n=303). IFN-α production by plasmacytoid dendritic cells (pDCs) was analysed after stimulation with TLR9 ligand CpG-ODN (n=220).Results No significant influence of common TLR9 polymorphisms and haplotypes on the total and specific IgE levels was found. Functional analysis of CpG-ODN-induced IFN-α did not indicate a significant role for common TLR9 gene polymorphisms in TLR9 function.Conclusion We conclude that common genetic differences in the TLR9 gene exert no major influence on allergy susceptibility, and are unlikely to have on impact on clinical application of CpG-ODNs.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2222.2005.02325.x

    Articles: DFG German National Licenses
  16. 16
    Botha, V.P. ; Ziegler, A. ; Haiduc, I.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0020-1693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0020-1693(00)81925-8

    Articles: DFG German National Licenses
  17. 17
    Ziegler, A. ; Kisielowski, C. ; Hoffmann, M. J. ; Ritchie, R. O.

    Westerville, Ohio : American Ceramics Society
    Published 2003
    Staff View
    ISSN:
    1551-2916
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Physics
    Notes:
    High-resolution transmission electron microscopy (HRTEM) employing focus-variation phase-reconstruction methods is used to image the atomic structure of grain boundaries in a silicon nitride ceramic at subangstrom resolution. Complementary energy-dispersive X-ray emission spectroscopy experiments revealed the presence of yttrium ions segregated to the 0.5–0.7-nm thin amorphous boundary layers that separate individual grains. Our objective here is probing if yttrium ions attach to the prismatic planes of the Si3N4 at the interface toward the amorphous layer, using Scherzer and phase-reconstruction imaging, as well as image simulation. Crystal structure images of grain boundaries in thin sample (〈100 Å) areas do not reveal the attachment of yttrium at these positions, although lattice images from thicker areas do suggest the presence of yttrium at these sites. It is concluded that most of the yttrium atoms are located in the amorphous phase and only a few atoms may attach to the terminating prism plane. In this case, the line concentrations of such yttrium in the latter location are estimated to be at most one yttrium atom every 17 Å.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1151-2916.2003.tb03554.x

    Articles: DFG German National Licenses
  18. 18
    Ziegler, A. ; McNaney, J. M. ; Hoffmann, M. J. ; Ritchie, R. O.

    Oxford, UK : Blackwell Science Inc
    Published 2005
    Staff View
    ISSN:
    1551-2916
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Physics
    Notes:
    The effects of grain-boundary chemistry on the mechanical properties of high-purity silicon nitride ceramics have been investigated, specifically involving the role of oxygen, present along the grain boundaries, in influencing the fracture behavior. To avoid complications from inadvertently introduced impurities, studies were performed on a high-purity Si3N4 processed using two-step gas-pressure-HIP sintering. Varying the grain-boundary oxygen content, which was achieved by control of oxidizing heat treatments and sintering additives, was found to result in a transition in fracture mechanism, from transgranular to intergranular fracture, with an associated increase in fracture toughness. This phenomenon is correlated to an oxygen-induced change in grain-boundary chemistry and possibly to a concomitant structural transformation along the interface. The incorporation of oxygen appears to affect fracture by “weakening” the interface, thus facilitating debonding and crack advance along the boundaries, and hence to toughening by grain bridging. It is concluded that if the oxygen content in the thin grain-boundary films exceeds a lower limit, which is ∼0.87 equiv% oxygen content, then the interfacial structure and bonding characteristics favor intergranular debonding during crack propagation; otherwise, transgranular fracture ensues.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1551-2916.2005.00412.x

    Articles: DFG German National Licenses
  19. 19
    Reich, K. ; Westphal, G. ; König, I.R. ; Mössner, R. ; Schupp, P. ; Gutgesell, C. ; Hallier, E. ; Ziegler, A. ; Neumann, C.

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Summary Background Atopic dermatitis (AD) and psoriasis are genetically determined inflammatory skin disorders characterized by abnormal cytokine production. From association studies there is evidence that functionally relevant cytokine gene polymorphisms contribute to the genetic basis of psoriasis. Association studies in AD have mostly been limited to polymorphisms of T-helper 2-type cytokines, which dominate in acute AD lesions. Unexpectedly, the results of recent genome scans indicate linkage of AD to psoriasis susceptibility loci. Therefore, AD may also be influenced by genes that modulate cutaneous inflammation independently from atopic mechanisms. Objectives To investigate further the role of cytokine gene polymorphisms in AD. Methods Polymorphisms in the genes encoding tumour necrosis factor-α (TNFA−238 G/A, −308 G/A), interleukin (IL)-1β (IL1B−511 T/C, +3953 T/C), IL-6 (IL6−174 C/G), IL-10 (IL10−1082 A/G) and the IL-1 receptor antagonist (IL1RN intron 2) were investigated in German patients with AD (n = 94) and in healthy nonatopic individuals (n = 214) by polymerase chain reaction-based methods and direct cycle sequencing. Results No association was found between AD and any of the polymorphisms analysed. This is in contrast to the recently described association between psoriasis and the TNFA−238 and IL1B−511 polymorphisms. Conclusions Our data indicate that cytokine gene polymorphisms may act as specific markers of inflammatory skin diseases rather than contribute to a general disposition towards cutaneous inflammation.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2133.2003.05307.x

    Articles: DFG German National Licenses
  20. 20
    ZIEGLER, A. M.

    [s.l.] : Nature Publishing Group
    Published 1965
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] PETERSEN1, in a classic investigation in marine JL ecology, demonstrated that the benthonic animals of Danish waters tend to occur in several distinctive communities, and he produced maps showing the distribution of these communities. Other workers2'3 have followed Petersen's lead in treating the ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/207270a0

    Articles: DFG German National Licenses