Search Results - (Author, Cooperation:A. Vortmeyer)

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  1. 1
    Staff View
    Publication Date:
    2013-01-26
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adult ; Aged ; Aged, 80 and over ; Brain Neoplasms/classification/*genetics/pathology ; Chromosomes, Human, Pair 22/genetics ; DNA Mutational Analysis ; Female ; Genes, Neurofibromatosis 2 ; Genomic Instability ; Genomics ; Humans ; Kruppel-Like Transcription Factors/*genetics ; Male ; Meningeal Neoplasms/classification/*genetics/pathology ; Meningioma/classification/*genetics/pathology ; Middle Aged ; Mutation ; Neoplasm Grading ; Proto-Oncogene Proteins c-akt/*genetics ; Receptors, G-Protein-Coupled/*genetics ; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins/*genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2011-10-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aging/*genetics ; Brain/embryology/*growth & development/*metabolism ; Child ; Child, Preschool ; Exons/genetics ; Female ; Fetus/metabolism ; *Gene Expression Profiling ; Gene Expression Regulation, Developmental/*genetics ; Gene Regulatory Networks/genetics ; Humans ; Infant ; Male ; Middle Aged ; Quality Control ; Quantitative Trait Loci/genetics ; Sex Characteristics ; Time Factors ; Transcriptome/*genetics ; Young Adult
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Vortmeyer, A. O. ; Colmant, H. J.
    Springer
    Published 1988
    Staff View
    ISSN:
    1432-2307
    Keywords:
    Metabolic Brain Diseases ; Thiamine deficiency ; Wernicke's Encephalopathy ; Hypothermia
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Dietary deprivation of thiamine combined with pyrithiamine administration in rats was used for pathophysiological and morphological investigations. The animals passed through three different symptomatic stages, ranging from slight neurological abnormalities to generalized seizures from day 8 up to day 11. Hypothermia was a consistent finding during the second week. Histological examination revealed two types of neuropathological lesions in the rats. Those in the colliculi inferiores and the vestibular nuclei were characterized by a bullous spongiform appearance of the neuropil with severely damaged, pale and oedematous nerve cells. Alterations in the thalamus and inferior olives, however, showed eosinophilic nerve cell necrosis of the ischaemic type which resembles the thalamic pathology found in human cases of Wernicke's encepalopathy.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1432-0533
    Keywords:
    Key words Nerve ; Neurocutaneous ; Onion bulb ; Schwann ; Trigeminal
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Onion bulbs are concentric lamellar structures formed by Schwann or perineurial cells, which may be seen in several generalized or localized diseases of the peripheral nerve. There is debate regarding the pathogenesis of localized tumefactions displaying these microscopic structures. We report the fifth case, to our knowledge, of a Schwann cell-onion bulb tumor, which arose in the trigeminal nerve of a child with an unclassifiable, probably distinct, neurocutaneous syndrome; we also provide evidence for a neoplastic or hamartomatous origin. Molecular studies failed to establish an abnormality in the NF1, NF2, PMP22, or Connexin 32 genes. Similar and previously reported cases are discussed, as well as other onion bulb-forming entities.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1432-1076
    Keywords:
    Chrodoma ; Skull neoplasms ; Neonatal intracranial tumour ; Neonatal hydrocephalus ; Craniotomy
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract We report the first case of a congenital intracranial chordoma. Hydrocephalus, sixth and seventh cranial nerve palsy, and torticollis were observed shortly after birth. The tumour was delineated by sonography, CT scans and MRI and the diagnosis confirmed after subtotal resection at the end of the newborn period.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses