Search Results - (Author, Cooperation:A. V. Emelyanov)

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  1. 1
    X. Lu ; S. N. Wontakal ; H. Kavi ; B. J. Kim ; P. M. Guzzardo ; A. V. Emelyanov ; N. Xu ; G. J. Hannon ; J. Zavadil ; D. V. Fyodorov ; A. I. Skoultchi
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-04-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Drosophila Proteins/genetics/*metabolism ; Drosophila melanogaster/*genetics ; *Gene Silencing ; Heterochromatin/*metabolism ; Histones/genetics/*metabolism ; Muscle Proteins/genetics ; RNA Interference ; Repetitive Sequences, Nucleic Acid/*genetics ; Repressor Proteins/*metabolism ; Transcription Factors/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Nabatov, A. A. ; Masharsky, A. E. ; Verevochkin, S. V. ; Emelyanov, A. V. ; Kozlov, A. P.

    Oxford, UK; Malden, USA : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The previous studies of anti-HIV-1 humoral immune response have found the stable individual structural bias in the antibody production that reflects the changes in the immune functional network caused by HIV-1. The correlation between antigen structure, in particular the V3 domain of HIV-1, and the serum specificity to the structure remains unclear. To clarify the role of host individual factors in the serum specificity, we used the slightly modified HIV-1 serotyping methodological approach for the sera of the patients infected with HIV-1 with a different level of genetic similarity. Substantial discrepancy between serum specificities and antigen structure was found. Patients infected with HIV-1 carrying similar and identical V3 sequences had significantly different serum specificities. The opposite situation was often observed as well. The results of the study suggest that the influence of the V3 loop structure in the development of humoral immune response to the V3 loop is substantially modified in a patient-specific manner.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses