Search Results - (Author, Cooperation:A. Tracey)

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  1. 1
    K. Howe ; M. D. Clark ; C. F. Torroja ; J. Torrance ; C. Berthelot ; M. Muffato ; J. E. Collins ; S. Humphray ; K. McLaren ; L. Matthews ; S. McLaren ; I. Sealy ; M. Caccamo ; C. Churcher ; C. Scott ; J. C. Barrett ; R. Koch ; G. J. Rauch ; S. White ; W. Chow ; B. Kilian ; L. T. Quintais ; J. A. Guerra-Assuncao ; Y. Zhou ; Y. Gu ; J. Yen ; J. H. Vogel ; T. Eyre ; S. Redmond ; R. Banerjee ; J. Chi ; B. Fu ; E. Langley ; S. F. Maguire ; G. K. Laird ; D. Lloyd ; E. Kenyon ; S. Donaldson ; H. Sehra ; J. Almeida-King ; J. Loveland ; S. Trevanion ; M. Jones ; M. Quail ; D. Willey ; A. Hunt ; J. Burton ; S. Sims ; K. McLay ; B. Plumb ; J. Davis ; C. Clee ; K. Oliver ; R. Clark ; C. Riddle ; D. Elliot ; G. Threadgold ; G. Harden ; D. Ware ; S. Begum ; B. Mortimore ; G. Kerry ; P. Heath ; B. Phillimore ; A. Tracey ; N. Corby ; M. Dunn ; C. Johnson ; J. Wood ; S. Clark ; S. Pelan ; G. Griffiths ; M. Smith ; R. Glithero ; P. Howden ; N. Barker ; C. Lloyd ; C. Stevens ; J. Harley ; K. Holt ; G. Panagiotidis ; J. Lovell ; H. Beasley ; C. Henderson ; D. Gordon ; K. Auger ; D. Wright ; J. Collins ; C. Raisen ; L. Dyer ; K. Leung ; L. Robertson ; K. Ambridge ; D. Leongamornlert ; S. McGuire ; R. Gilderthorp ; C. Griffiths ; D. Manthravadi ; S. Nichol ; G. Barker ; S. Whitehead ; M. Kay ; J. Brown ; C. Murnane ; E. Gray ; M. Humphries ; N. Sycamore ; D. Barker ; D. Saunders ; J. Wallis ; A. Babbage ; S. Hammond ; M. Mashreghi-Mohammadi ; L. Barr ; S. Martin ; P. Wray ; A. Ellington ; N. Matthews ; M. Ellwood ; R. Woodmansey ; G. Clark ; J. Cooper ; A. Tromans ; D. Grafham ; C. Skuce ; R. Pandian ; R. Andrews ; E. Harrison ; A. Kimberley ; J. Garnett ; N. Fosker ; R. Hall ; P. Garner ; D. Kelly ; C. Bird ; S. Palmer ; I. Gehring ; A. Berger ; C. M. Dooley ; Z. Ersan-Urun ; C. Eser ; H. Geiger ; M. Geisler ; L. Karotki ; A. Kirn ; J. Konantz ; M. Konantz ; M. Oberlander ; S. Rudolph-Geiger ; M. Teucke ; C. Lanz ; G. Raddatz ; K. Osoegawa ; B. Zhu ; A. Rapp ; S. Widaa ; C. Langford ; F. Yang ; S. C. Schuster ; N. P. Carter ; J. Harrow ; Z. Ning ; J. Herrero ; S. M. Searle ; A. Enright ; R. Geisler ; R. H. Plasterk ; C. Lee ; M. Westerfield ; P. J. de Jong ; L. I. Zon ; J. H. Postlethwait ; C. Nusslein-Volhard ; T. J. Hubbard ; H. Roest Crollius ; J. Rogers ; D. L. Stemple
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-04-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Chromosomes/genetics ; Conserved Sequence/*genetics ; Evolution, Molecular ; Female ; Genes/genetics ; Genome/*genetics ; Genome, Human/genetics ; Genomics ; Humans ; Male ; Meiosis/genetics ; Molecular Sequence Annotation ; Pseudogenes/genetics ; Reference Standards ; Sex Determination Processes/genetics ; Zebrafish/*genetics ; Zebrafish Proteins/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2013-03-15
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adaptation, Physiological/*genetics ; Animals ; Biological Evolution ; Cestoda/drug effects/*genetics/physiology ; Cestode Infections/drug therapy/metabolism ; Conserved Sequence/genetics ; Echinococcus granulosus/genetics ; Echinococcus multilocularis/drug effects/genetics/metabolism ; Genes, Helminth/genetics ; Genes, Homeobox/genetics ; Genome, Helminth/*genetics ; HSP70 Heat-Shock Proteins/genetics ; Humans ; Hymenolepis/genetics ; Metabolic Networks and Pathways/genetics ; Molecular Targeted Therapy ; Parasites/drug effects/*genetics/physiology ; Proteome/genetics ; Stem Cells/cytology/metabolism ; Taenia solium/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-05-26
    Publisher:
    The American Society for Biochemistry and Molecular Biology (ASBMB)
    Print ISSN:
    0021-9258
    Electronic ISSN:
    1083-351X
    Topics:
    Biology
    Chemistry and Pharmacology
    Published by:
    http://www.asbmb.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Johnston, Tracey A. ; Greer, Ian A. ; Kelly, Rodney W. ; Calder, Andrew A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1993
    Staff View
    ISSN:
    1471-0528
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Objective To determine the concentrations of the metabolites of prostaglandin E2 (PGEM) and of prosta-glandin F2α (PGFM) prior to the onset of labour and during spontaneous labour, and to correlate the changes in concentrations of these metabolites with labour outcome.Design Longitudinal study throughout labour.Setting Labour ward of a large maternity unit.Subjects Seven primigravid and 11 parous women in the late third trimester with no signs of labour, and 17 primigravid and 11 parous women in spontaneous labour.Interventions Six of the primigravid women required augmentation with oxytocin because of dysfunctional labour.Results Before labour, parous women had significantly higher concentrations of both PGEM (P〈0.007) and PGFM (P〈0.006) compared with primigravid women. During labour, PGFM concentrations were significantly higher in both primigravid (P〈0.0002) and parous (P〈0.0001) women compared with the concentrations of these metabolites in women not in labour; the same was true for PGEM in primigravid (P〈0.003) but not in parous (P= 0.1) women. There was a small but significant increase (P〈0.02) in PGEM as labour progressed in both the normal groups. Amniotomy was associated with a significant increase in PGFM in primigravid and parous women (P〈0.002 and P〈0.009, respectively). The concentration of PGFM one hour following amniotomy correlated inversely with the amniotomy to delivery interval in both the normal primigravid (r=−0.624; P= 0.04) and the parous (r= 0.745; P= 0.021) groups. Women with dysfunctional labour showed no significant rise in PGEM or PGFM. Their PGFM concentrations were significantly lower than those seen in normal labour (P〈0.05). The concentration of PGFM in cord blood was significantly higher (P〈0.0001) in the parous women who laboured than in women delivered by elective caesarean section. There was no difference in the corresponding concentrations of PGEM (P= 0.9).Conclusions These data show that spontaneous labour is associated with increased concentrations of prostaglandin metabolites in the maternal plasma, and are consistent with PGF2α being an important stimulator of uterine contractility, with a relative deficiency of PGF2α being associated with dysfunctional labour.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-0528.1993.tb15277.x

    Articles: DFG German National Licenses
  5. 5
    Oyarce, Ana Maria ; Hand, Tracey A. ; Mains, Richard E. ; Eipper, Betty A.

    Oxford, UK : Blackwell Science Ltd
    Published 1996
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: The biosynthesis of peptides requires the synthesis of the prohormone, several biosynthetic processing enzymes, and other granule constituents. We have investigated the regulated expression of proopiomelanocortin (POMC) and five enzymes essential for the processing of POMC to smaller, bioactive peptides in intermediate pituitary melanotropes. Rats were treated with a dopaminergic agonist (bromocriptine) or antagonist (haloperidol) for periods ranging from 1 h to 5 days, followed by analyses of mRNA levels and protein biosynthetic rates. Multiplex RNase protection assays showed that bromocriptine treatment caused a striking decrease in POMC mRNA levels, and significant decreases in mRNA levels for prohormone convertase 2 (PC2), carboxypeptidase H (CPH), and peptidylglycine α-amidating monooxygenase (PAM). Smaller increases in mRNA levels were seen after haloperidol stimulation. Protein biosynthetic rates changed more profoundly than mRNA levels at short drug treatment times, indicating a role for translational effects after treatment with bromocriptine and with haloperidol. The homogeneous population of melanotropes in the intermediate lobe of the pituitary allows a quantitative analysis of transcript levels and biosynthetic rates. POMC mRNA levels are 200–1,000-fold higher than levels of any of the processing enzyme mRNAs, and POMC biosynthetic rates exceed those of PC2, PC1, and PAM by 1,000–10,000-fold.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1471-4159.1996.67010229.x

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1471-4159.2003.01790.x

    Articles: DFG German National Licenses
  7. 7
    MARTIN, FIONA L. ; PARKER, ALAN ; HORT, JOANNE ; HOLLOWOOD, TRACEY A. ; TAYLOR, ANDREW J.

    Oxford, UK and Malden, USA : Blackwell Science Inc
    Published 2005
    Staff View
    ISSN:
    1745-4603
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    The relationship between vane geometry measurements and sensory perceptions of stirred yogurt texture was investigated. Descriptive profiling showed that the main perceptible textural difference between six commercial stirred yogurts was thickness (both visual and in-mouth). The yogurts were analyzed using the vane with a low constant rotation rate (generation of overshoot curves). Correlations with parameters extracted from the overshoot curves were significant for both visual and in-mouth thickness, but were higher for visual thickness. Visual thickness correlated highest with the maximum apparent stress. The maximum stress in an overshoot curve is often quoted to be equal to the material's yield stress. This was not found to be the case as the overshoot maximum decreased when the rotation rate was lowered. The physical nature of the visual thickness test was investigated to further aid interpretation of the results.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1745-4603.2005.00025.x

    Articles: DFG German National Licenses
  8. 8
    Laszloffy, Tracey A. ; Hardy, Kenneth V.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2000
    Staff View
    ISSN:
    1545-5300
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Psychology
    Notes:
    Race and racism have a profound effect on our daily lives and the practice of family therapy. Whether individual or institutional level, overt or covert, intentional or unintentional, there are a variety of ways in which racism can infiltrate the therapeutic process. Before therapists can take steps to address racism effectively within the context of family therapy, it is important to attend to the development of their racial awareness and racial sensitivity. These provide the critical foundation upon which specific skills and strategies associated with effectively identifying and responding to racism in therapy are based. This article defines racial awareness and sensitivity and provides suggestions for enhancing both. In the section that follows, three major ways in which racism can infiltrate the therapeutic process are described. Skills and strategies for addressing each of these in family therapy are presented.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1545-5300.2000.39106.x

    Articles: DFG German National Licenses
  9. 9
    Swift, Tracey A. ; Humphrey, Christopher ; Gor, Vishal

    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Published 2000
    Staff View
    ISSN:
    1467-8551
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Economics
    Notes:
    In recent years there appears to have been a veritable boom in the provision of ‘quality audits’– that is, audits of organizations' production processes and management systems. Despite the rising significance of this international audit movement affecting hundreds of thousands of organizations world-wide, there has been limited interest in, or critique of, the practice of quality audit by academic auditing researchers. This paper traces the history of quality assurance standards and auditing and finds that quality auditing is not simply an outgrowth of an engineering inspection function. Rather, for several decades, quality auditors have consciously modelled their practice on that of the statutory financial audit, which in turn, exposes them to similar issues with regard to the long standing ‘expectations gap’ debate. Yet, despite what the authors argue are critical links with the financial audit, there has not been any notable involvement on the part of the accounting profession with quality auditing. The growing demand for ‘added-value’ audits poses considerable questions for the future development and organizational significance of quality auditing. Current developments in both quality and financial audit services suggest that these two influential audit movements are now competing against each other to promote business excellence and contribute to business strategy.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/1467-8551.00149

    Articles: DFG German National Licenses
  10. 10
    Vadeyar, Shantala ; Johnston, Tracey A. ; Sidebotham, Mary ; Sands, Jean

    Oxford, UK and Malden, USA : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1471-0528
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The aim of this study was to look at neonatal death following termination of pregnancy in 31 cases over a six-year period in our region and to determine why this was occurring. We have highlighted two main areas of concern: failure to perform feticide in keeping with RCOG advice, and classification and registration below the clinical limit of viability. In these circumstances, appropriate counselling of the family and an antenatal plan for the postnatal care of the dying infant made prior to delivery are essential. We question the rationale of the existing classification and registration requirements below the clinical limit of viability.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-0528.2005.00648.x

    Articles: DFG German National Licenses
  11. 11
    Hardy, Kenneth V. ; Laszloffy, Tracey A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1752-0606
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Psychology
    Notes:
    Training programs committed to the development of culturally competent family therapists must discover ways to raise cultural awareness and increase cultural sensitivity. While awareness involves gaining knowledge of various cultural groups, sensitivity involves having experiences that challenge individuals to explore their personal cultural issues. This article outlines how the cultural genogram can be used as an effective training tool to promote both cultural awareness and sensitivity.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1752-0606.1995.tb00158.x

    Articles: DFG German National Licenses
  12. 12
    Laszloffy, Tracey A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2000
    Staff View
    ISSN:
    1752-0606
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1752-0606.2000.tb00308.x

    Articles: DFG German National Licenses
  13. 13
    Gillman, Tracey A. ; Pennefather, Jocelyn N.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1998
    Staff View
    ISSN:
    1440-1681
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    1. Adenosine, adenosine triphosphate (ATP) and some stable analogues of adenosine inhibited field stimulation-induced contractions of the uterus from rats treated with oestradiol cypionate (20 μg/kg, s.c.) 1 day previously. Adenosine was twice as potent as ATP; both were potentiated by dipyridamole (10 μmol/L).2. The order of agonist potency of adenosine and its analogues was: 5′-N-ethyIcarboxamidoadenosine (NECA) 〉N6-cyclohexyl-adenosine ≥ R-phenylisopropyladenosine = s-phenylisopropyl-adenosine = 2-chIoroadenosine ≥ adenosine ≥ ATP ≫ 2-p-(2-carboxyethyl) phenethylarnino-5′-N-ethylcarboxamido-adenosine. This order suggests the presence of P1 purinoceptors of the A2B subtype.3. Responses to agonists were antagonized to differing extents by the P1 purinoceptor antagonist 8-phenyltheophylline (10μ-mol/L).4. In uterine preparations from rats pretreated for 2 days with oestrogen (20 μg/kg, s.c.) and for 1 day with progesterone (3 mg/animal, s.c), the inhibitory potencies of adenosine and NECA were reduced, indicating hormonal regulation of uterine responsiveness to P1 purinoceptor agonists.5. Stable analogues of ATP caused contractions of unstimulated myometrial preparations from oestrogen-treated animals, indicating activation of a P2 purinoceptor, possibly of the P2x subtype, because the relative order of potency was α,β-methylene ATP〉 β, γ-methylene ATP = ATP = 2-methylthioATP.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1440-1681.1998.tb02257.x

    Articles: DFG German National Licenses
  14. 14
    Gaspari, Tracey A ; Barber, Melissa N ; Woods, Robyn L ; Dusting, Gregory J

    Melbourne, Australia : Blackwell Science Pty
    Published 2000
    Staff View
    ISSN:
    1440-1681
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    1. We investigated the effect of local administration of type-C natriuretic peptide (CNP) on the endothelial dysfunction and development of an atheroma-like neointima induced by a peri-arterial collar in rabbits.2. Peri-arterial collars were placed on both common carotid arteries allowing local treatment of the collared region with either CNP (10 μmol/L) or saline. After 7 days, uncollared (control) and collared sections were taken from both arteries for pharmacological and morphological analysis.3. Application of the collar markedly attenuated (P 〈 0.05) endothelium-dependent vasorelaxation induced by acetylcholine (ACh); inhibition of 5-hydroxytryptamine contraction was 80±5% in control sections compared with 44±4% in collared sections from the same arteries. Local infusion of CNP (10 μmol/L) into the collar restored ACh-induced vasorelaxation (74±3% from collared arteries + CNP vs 77±2% from control sections from the same arteries).4. Type-C natriuretic peptide treatment also reduced (P 〈 0.05) intimal thickening compared with contralateral collared arteries (intima/media ratio 0.06±0.01 vs 0.16±0.01).5. These results provide evidence that locally administered CNP is effective in preventing the endothelial dysfunction and development of a neointima in this model.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1440-1681.2000.03297.x

    Articles: DFG German National Licenses
  15. 15
    Cook, David J. ; Hollowood, Tracey A. ; Linforth, Robert S. T. ; Taylor, Andrew J.

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2621
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Attempts to correlate sensory perception with analytical measurement of the physical or chemical properties of a food are widespread in both industry and academia. Reasons for this are discussed, along with some of the techniques employed. The inter-relationship between instrumental analysis and sensory evaluation in the development and quality control of food products is emphasized. Three examples are drawn from the field of flavour research, where a combination of instrumental and sensory techniques was used for different purposes. Instrumental measures may be used to predict sensory quality within a known design space, provided this has first been validated with appropriate sensory methodology. It is true, however, that a significant correlation between analytical and sensory data does not necessarily imply that a causal relationship exists between the two.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2621.2005.00973.x

    Articles: DFG German National Licenses
  16. 16
    Rouault, Tracey A.

    [s.l.] : Nature Publishing Group
    Published 2001
    Staff View
    ISSN:
    1546-1718
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Medicine
    Notes:
    [Auszug] For many years it has been well accepted that accumulations of iron in organs such as the liver and heart can cause disease. In disorders such as genetic hemochromatosis and thalassemia, hepatic iron overload causes cirrhosis; cardiac iron overload leads to heart failure. Accumulations of iron are ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/91036

    Articles: DFG German National Licenses
  17. 17
    Ghosh, Manik C ; Ollivierre-Wilson, Hayden ; Cooperman, Sharon ; Rouault, Tracey A

    [s.l.] : Nature Publishing Group
    Published 2006
    Staff View
    ISSN:
    1546-1718
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Medicine
    Notes:
    [Auszug] Ghosh et al. reply: We previously reported that targeted deletion of Ireb2, the gene encoding iron regulatory protein 2 (IRP2), caused misregulation of iron metabolism in mice, including overexpression of ferritin and decreased expression of the transferrin receptor in multiple tissues, whereas ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/ng0906-969

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1546-1718
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Medicine
    Notes:
    [Auszug] In mammalian cells, regulation of the expression of proteins involved in iron metabolism is achieved through interactions of iron-sensing proteins known as iron regulatory proteins (IRPs), with transcripts that contain RNA stem-loop structures referred to as iron responsive elements (IREs). Two ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/84859

    Articles: DFG German National Licenses
  19. 19
    Revenson, Tracey A. ; Johnson, Jeffrey L.

    New York : Periodicals Archive Online (PAO)
    Published 1984
    Staff View
    ISSN:
    0091-0562
    Topics:
    Psychology
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:c034-1984-012-01-000005

    Articles: DFG German National Licenses
  20. 20
    Aldwin, Carolyn M. ; Revenson, Tracey A.

    New York : Periodicals Archive Online (PAO)
    Published 1986
    Staff View
    ISSN:
    0091-0562
    Topics:
    Psychology
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:c034-1986-014-02-000006

    Articles: DFG German National Licenses