Search Results - (Author, Cooperation:A. Suarez)

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  1. 1
    Staff View
    Publication Date:
    2018-05-26
    Publisher:
    The American Society for Biochemistry and Molecular Biology (ASBMB)
    Print ISSN:
    0021-9258
    Electronic ISSN:
    1083-351X
    Topics:
    Biology
    Chemistry and Pharmacology
    Published by:
    http://www.asbmb.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-06-05
    Publisher:
    Nature Publishing Group (NPG)
    Electronic ISSN:
    2045-2322
    Topics:
    Natural Sciences in General
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-04-03
    Publisher:
    The American Association for Cancer Research (AACR)
    Print ISSN:
    0008-5472
    Electronic ISSN:
    1538-7445
    Topics:
    Medicine
    Published by:
    http://www.aacr.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-05-16
    Publisher:
    BMJ Publishing
    Electronic ISSN:
    2044-6055
    Topics:
    Medicine
    Keywords:
    Geriatric medicine, Open access, Haematology (incl blood transfusion)
    Published by:
    http://group.bmj.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    N. Annaluru ; H. Muller ; L. A. Mitchell ; S. Ramalingam ; G. Stracquadanio ; S. M. Richardson ; J. S. Dymond ; Z. Kuang ; L. Z. Scheifele ; E. M. Cooper ; Y. Cai ; K. Zeller ; N. Agmon ; J. S. Han ; M. Hadjithomas ; J. Tullman ; K. Caravelli ; K. Cirelli ; Z. Guo ; V. London ; A. Yeluru ; S. Murugan ; K. Kandavelou ; N. Agier ; G. Fischer ; K. Yang ; J. A. Martin ; M. Bilgel ; P. Bohutski ; K. M. Boulier ; B. J. Capaldo ; J. Chang ; K. Charoen ; W. J. Choi ; P. Deng ; J. E. DiCarlo ; J. Doong ; J. Dunn ; J. I. Feinberg ; C. Fernandez ; C. E. Floria ; D. Gladowski ; P. Hadidi ; I. Ishizuka ; J. Jabbari ; C. Y. Lau ; P. A. Lee ; S. Li ; D. Lin ; M. E. Linder ; J. Ling ; J. Liu ; M. London ; H. Ma ; J. Mao ; J. E. McDade ; A. McMillan ; A. M. Moore ; W. C. Oh ; Y. Ouyang ; R. Patel ; M. Paul ; L. C. Paulsen ; J. Qiu ; A. Rhee ; M. G. Rubashkin ; I. Y. Soh ; N. E. Sotuyo ; V. Srinivas ; A. Suarez ; A. Wong ; R. Wong ; W. R. Xie ; Y. Xu ; A. T. Yu ; R. Koszul ; J. S. Bader ; J. D. Boeke ; S. Chandrasegaran
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-03-29
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Base Sequence ; *Chromosomes, Fungal/genetics/metabolism ; DNA, Fungal/genetics ; Genes, Fungal ; Genetic Fitness ; Genome, Fungal ; Genomic Instability ; Introns ; Molecular Sequence Data ; Mutation ; Polymerase Chain Reaction ; RNA, Fungal/genetics ; RNA, Transfer/genetics ; Saccharomyces cerevisiae/cytology/*genetics/physiology ; Sequence Analysis, DNA ; Sequence Deletion ; Synthetic Biology/*methods ; Transformation, Genetic
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    ISSN:
    1435-1536
    Keywords:
    Micelles ; micelle size ; fluorescence ; polar additives
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract The steady-state fluorescence quenching technique was used to investigate the effect of the presence of a series of alcohol homologues of mid-sized straight chain on the size of mixed micelles of sodium dodecyl sulfate (SDS). We used pyrene at concentration of ca. 10−6M, where only its monomer exhibits any fluorescence, as fluorescent probe, and cetylpiridinium chloride at concentrations in the range (1–9)×10−5 M as quencher. This technique allows one to determine the micellar aggregation number. The number of alcohol molecules per micelle was calculated from reported values for the micelle-water partition coefficient. On the assumption of spherical micelles, their hydrophobic radii was then calculated. The hypothesis that micelle size is determined by the available surface area per charged headgroup is discussed in the light of the results obtained.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00657637

    Articles: DFG German National Licenses
  7. 7
    Staff View
    Publication Date:
    2018-04-07
    Publisher:
    BMJ Publishing Group
    Print ISSN:
    0017-5749
    Electronic ISSN:
    1468-3288
    Topics:
    Medicine
    Keywords:
    Open access
    Published by:
    http://www.bmj.com/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2018-01-04
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1755-1307
    Electronic ISSN:
    1755-1315
    Topics:
    Geography
    Geosciences
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Staff View
    Publication Date:
    2018-04-14
    Publisher:
    BMJ Publishing
    Electronic ISSN:
    2044-6055
    Topics:
    Medicine
    Keywords:
    Open access, Rehabilitation medicine
    Published by:
    http://group.bmj.com/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Mozo, L. ; Suárez, A. ; Gutiérrez, C.

    Oxford, UK : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background IL-10 plays an immunosuppressive role in inflammatory responses. Increased plasma levels of IL-10 have been detected in patients under glucocorticoid (GC) therapy, indicating that steroids may exert their suppressive effect, in part, by increasing IL-10 production.Objectives The aim was to define possible mechanisms by which steroids up-regulate IL-10 production. To this end, we have analysed ex vivo the effect of GCs on the constitutive production of IL-10 by lymphocytes and cells of myeloid origin.Methods Monocytes and T cells were isolated by a Percoll gradient and B cells were purified by rosetting. Protein and mRNA IL-10 levels were determined by ELISA and by Northern blot, respectively.Results Monocytes, but not T or B cells, up-regulated the constitutive production of IL-10 following pre-treatment for at least 12 h with physiological doses of dexamethasone (Dex). Up-regulation of IL-10 occurred at both protein and mRNA levels, probably indicating that the effect of Dex was by incrementing gene transcription. Other steroids had similar outcomes, their effects being dose-related, proportional to the steroid potency and totally reversed by the steroid antagonist RU486. Thus, transcript levels of IL-10 were up-regulated by GCs probably through binding of the GC receptor to its specific glucocorticoid response element sequence in the IL-10 promoter. In contrast to monocytes, differentiated immature macrophages and dendritic cells did not vary their constitutive IL-10 production after pre-treatment with Dex.Conclusion Our results support the fact that steroids up-regulate constitutive IL-10 production by selectively triggering activation signals on monocytes.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2222.2004.01824.x

    Articles: DFG German National Licenses
  11. 11
    García-Abujeta, J. L. ; Martín-Gil, D. ; Martín, M. ; López, R. ; Suárez, A. ; Rodríguez, F. ; Jerez, J. ; López-Hoyos, M.

    Copenhagen : Munksgaard International Publishers
    Published 2001
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background: An altered production of cytokines has been described in Gleich's syndrome. Our aim was to study the cytokine production at the single-cell level in a patient with Gleich's syndrome and to determine whether it changed during a flare episode. Methods: Blood samples were obtained from a 30-year-old woman diagnosed with Gleich's syndrome before and during the subsequent flare of edema of trunk and arms and weight gain. The major lymphoid subsets (CD4+, CD8+, and CD19+) and natural killer (NK) cells were measured by flow cytometry. Cytokine-producing T cells (IL-2, IFN-γ, and IL-4) were quantified in whole blood by intracellular staining with specific monoclonal antibodies and flow cytometry analysis after polyclonal stimulation with phorbol 12-myristate 13-acetate and ionomycin. Results: Increased numbers of immature CD4+CD8+ T cells and NK cells were observed in peripheral blood during the asymptomatic period. The latter population significantly decreased during the flare. Type-1 cells were decreased in both asymptomatic and, more markedly, during the attack with respect to healthy subjects. Conclusions: The decreased type-1 response demonstrated in this patient might be the basis of the hypereosinophilia of Gleich's syndrome. Besides, the NK cells might play a role in the pathogenesis of these inflammatory episodes.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1034/j.1398-9995.2001.00287.x

    Articles: DFG German National Licenses
  12. 12
    Reimer, G.J. ; Suarez, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0021-9673
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0021-9673(01)87197-1

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    0020-1790
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0020-1790(74)90076-6

    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    0020-1790
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0020-1790(71)90076-X

    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    0020-1790
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0020-1790(72)90060-1

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    0022-1910
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0022-1910(74)90159-0

    Articles: DFG German National Licenses
  17. 17
    Staff View
    ISSN:
    0040-4020
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0040-4020(01)85914-7

    Articles: DFG German National Licenses
  18. 18
    Conde, G. ; Garcia-Barreno, P. ; Suarez, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-5793
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(80)80135-9

    Articles: DFG German National Licenses
  19. 19
    Staff View
    ISSN:
    0014-5793
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(81)80355-9

    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    0022-328X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0022-328X(00)99411-7

    Articles: DFG German National Licenses