Search Results - (Author, Cooperation:A. Sargent)

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  1. 1
    Staff View
    Publication Date:
    2015-04-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cell Differentiation/drug effects ; Cerebellum/drug effects/metabolism/pathology ; Clobetasol/*pharmacology ; Demyelinating Diseases/drug therapy/metabolism/pathology ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/drug therapy/metabolism/pathology ; Female ; Germ Layers/drug effects/metabolism/pathology ; Humans ; Lysophosphatidylcholines ; MAP Kinase Signaling System ; Male ; Mice ; Miconazole/*pharmacology ; Mitogen-Activated Protein Kinases/metabolism ; Multiple Sclerosis/*drug therapy/*metabolism/pathology ; Myelin Sheath/*drug effects/*metabolism ; Oligodendroglia/cytology/drug effects/metabolism ; Phenotype ; Pluripotent Stem Cells/cytology/*drug effects/metabolism ; Receptors, Glucocorticoid/metabolism ; Regeneration/drug effects ; Tissue Culture Techniques
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Circumstellar accretion disks transfer matter from molecular clouds to young stars and to the sites of planet formation. The disks observed around pre-main-sequence stars have properties consistent with those expected for the pre-solar nebula from which our own Solar System formed ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/35051033

    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    1572-946X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract The DEBRIS project is a search for infrared excess around Sun-like main sequence stars, and other types of stellar targets, using the Infrared Space Observatory. Some results, calibration issues, and changes to our original program are presented. Future platforms for advancing this project after the conclusion of the ISO mission are indicated.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1001119005084

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1432-8798
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Pre-pubertal immunisation of mice with a formalin-inactivated type 1 and 2 herpes simplex virus vaccine conferred a level of life-long protection against primary type 2 genital infection. Protection levels were better with type 1 vaccine and strikingly influenced by vaccine dosage where a one-hundred-fold reduction from the standard vaccine dosage diminished protection to insignificant levels. Vaccine efficacy was not significantly affected by the method of virus inactivation, the number of immunisations or the age of the mouse at immunisation. Vaccination conferred better protection than previous type 2 genital infection; this may be a consequence of a higher antigenic dose, more acceptable antigenic presentation or to a perversion of the immune response in a latently infected animal to homologous virus challenge.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01320618

    Articles: DFG German National Licenses
  5. 5
    Sargent, A. I. ; Beckwith, S. V. W.
    Springer
    Published 1994
    Staff View
    ISSN:
    1572-946X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract A variety of evidence suggests that at least 50% of low-mass stars are surrounded by disks of the gas and dust similar to the nebula that surrounded the Sun before the formation of the planets. The properties of these disks may bear strongly on the way in which planetary systems form and evolve. As a result of major instrumental developments over the last decade, it is now possible to detect and study the circumstellar environments of very young, solar-type stars in some detail, and to compare the results with theoretical models of the early solar system. For example, millimeter-wave aperture synthesis imaging provides a direct means of studying in detail the morphology, temperature and density distributions, velocity field and chemical constituents in the outer disks, while high resolution, near infrared spectroscopy probes the inner, warmer parts; the emergence of gaps in the disks, possibly reflecting the formation of planets, may be reflected in the variation of their dust continuum emission with wavelength. We review progress to date and discuss likely directions for future research.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00984522

    Articles: DFG German National Licenses