Search Results - (Author, Cooperation:A. Pradhan)
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1B. Baragana ; I. Hallyburton ; M. C. Lee ; N. R. Norcross ; R. Grimaldi ; T. D. Otto ; W. R. Proto ; A. M. Blagborough ; S. Meister ; G. Wirjanata ; A. Ruecker ; L. M. Upton ; T. S. Abraham ; M. J. Almeida ; A. Pradhan ; A. Porzelle ; M. S. Martinez ; J. M. Bolscher ; A. Woodland ; S. Norval ; F. Zuccotto ; J. Thomas ; F. Simeons ; L. Stojanovski ; M. Osuna-Cabello ; P. M. Brock ; T. S. Churcher ; K. A. Sala ; S. E. Zakutansky ; M. B. Jimenez-Diaz ; L. M. Sanz ; J. Riley ; R. Basak ; M. Campbell ; V. M. Avery ; R. W. Sauerwein ; K. J. Dechering ; R. Noviyanti ; B. Campo ; J. A. Frearson ; I. Angulo-Barturen ; S. Ferrer-Bazaga ; F. J. Gamo ; P. G. Wyatt ; D. Leroy ; P. Siegl ; M. J. Delves ; D. E. Kyle ; S. Wittlin ; J. Marfurt ; R. N. Price ; R. E. Sinden ; E. A. Winzeler ; S. A. Charman ; L. Bebrevska ; D. W. Gray ; S. Campbell ; A. H. Fairlamb ; P. A. Willis ; J. C. Rayner ; D. A. Fidock ; K. D. Read ; I. H. Gilbert
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-06-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antimalarials/administration & dosage/adverse ; effects/pharmacokinetics/*pharmacology ; Drug Discovery ; Female ; Gene Expression Regulation/*drug effects ; Life Cycle Stages/drug effects ; Liver/drug effects/parasitology ; Malaria/drug therapy/*parasitology ; Male ; Models, Molecular ; Peptide Elongation Factor 2/antagonists & inhibitors/metabolism ; Plasmodium/*drug effects/genetics/growth & development/*metabolism ; Plasmodium berghei/drug effects/physiology ; Plasmodium falciparum/drug effects/metabolism ; Plasmodium vivax/drug effects/metabolism ; Protein Biosynthesis/*drug effects ; Quinolines/administration & dosage/chemistry/pharmacokinetics/*pharmacologyPublished by: -
2Kumar, Shailendra ; Roy, S. B. ; Pradhan, A. K. ; Chaddah, P. ; Prasad, Ram ; Soni, N. C.
[S.l.] : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: A simple and interesting technique for measuring the Hc1 of the superconducting grains in bulk high Tc superconductor (HTSC) samples is presented herein. This technique takes advantage of interesting history effects observed in the nonlinear magnetic response of HTSC samples. The hysteretic second harmonic magnetization shows sharp structure at low applied fields due to the magnetic flux trapped inside the grains. This feature is used to track the penetration of magnetic field inside the superconducting granular regions.Type of Medium: Electronic ResourceURL: -
3Pradhan, A. K. ; Feng, Y. ; Wu, Y. ; Nakao, K. ; Koshizuka, N.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: We have studied the magnetotransport, magnetization properties, and microstructure of multifilamentary (Bi–Pb)2Sr2Ca2Cu3Ox (Bi-2223)/Ag tapes with varying filaments from 1 to 37 to explore the energy dissipation, reversible flux motion, and flux pinning related to the microstructure. Our results show that the dissipation is temperature, current, and magnetic field induced. The dissipation is thermally activated and the vortex liquid state is plastically deformed. The dissociation of vortex–antivortex pairs by current, magnetic field, and temperature plays a major role in enhancing the dissipation process, resulting in large broadening in the transition. We observed a reversible fluxoid motion of vortices. The critical current density follows an exponential dependence on the magnetic field. The weak links seem to be broken even for a field as low as 5 G even 12 K below the transition temperature. However, at low temperature, the weak links behave as superconducting. The microscopic characterizations show evidence for the dislocations, stacking faults, and misorientation of grains and grain boundaries that control the critical current in tapes. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Pradhan, A. K. ; Muralidhar, M. ; Koblischka, M. R. ; Murakami, M. ; Nakao, K. ; Koshizuka, N.
[S.l.] : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The flux pinning behavior of ternary melt-processed (Nd–Eu–Gd)Ba2Cu3Oy superconductors is studied with varying Gd2BaCuO5 second-phase (Gd-211) defect concentrations using magnetotransport and magnetization measurements. The critical current density, Jc increases with the addition of Gd-211 particles displaying a maximum value of Jc for 30% at zero and in intermediate field range and decreases on further addition of Gd-211 particles. A pronounced field-induced bump feature in the resistivity was observed. The dynamic scaling of the resistance suggests the low temperature phase as the vortex-glass phase. The current–voltage characteristics over the whole transition temperature regime show a linear flux–flow type behavior that favors the phenomenon of vortex entanglement in the liquid phase. The Nd/Ba substitution sites along with Gd-211 second-phase particles refined by the addition of a small amount of Pt are one of the possible reasons for the vortex entanglement in the liquid phase. The in-plane and out-of-plane resistance measurements clearly show the correlation of the vortices in the liquid state favoring some influence of twin planes and occasionally occurring natural grain boundaries on the liquid state as well. These defects give rise to high critical current density at low temperature with significant enhancement in pinning favoring the glassy phase to occur. © 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
5Pradhan, A. K. ; Muralidhar, M. ; Koblischka, M. R. ; Murakami, M. ; Nakao, K. ; Koshizuka, N.
Woodbury, NY : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: The flux pinning behavior of ternary melt-processed (Nd–Eu–Gd)Ba2Cu3Oy superconductors is studied with varying defect concentrations using magnetotransport and magnetization measurements. A huge field-induced bump feature in the resistivity with increasing defect density, field-induced magnetization kink and linear voltage-current (V-I) characteristics over the whole transition temperature regime favor the phenomenon of vortex entanglement in the liquid phase. The Nd/Ba substitution sites along with the fine second-phase particles are one of the possible reasons for the vortex entanglement and these defects give rise to high critical current density and reduced dissipation at low temperature with significant enhancement in pinning. © 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Pradhan, A. K. ; Muralidhar, M. ; Feng, Y. ; Murakami, M. ; Nakao, K. ; Koshizuka, N.
Woodbury, NY : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: The optimization of high-quality melt-processed ternary (Nd–Eu–Gd)Ba2Cu3O7−δ composite samples has been carried out to achieve the largest pinning. Our results suggest that the interaction between the twin planes and the fine second-phase precipitate forms a strongly pinned entangled vortex liquid in which vortices are correlated along the c axis. This pinned vortex liquid freezes into a glassy state at low temperature rendering high critical current density, Jc. The maximum Jc can be achieved in as-grown optimally annealed twinned sample with second phase precipitate without disturbing the twin influence. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We report measurements of the resistivity and magnetization of high-quality melt-processed La0.67Ca0.33MnO3 (LCM) and Sr-doped LCM materials that exhibit a sharp and enhanced metal–insulator transition (TMI) with significant colossal magnetoresistance (CMR) and two competing magnetic phases in the vicinity of TMI. Our results can well be explained using percolation in combination with the phase-separation scenario proposed for CMR. We propose that the spin polarization through grain boundaries and the enhanced grain connectivity between the ferromagnetic domains facilitate better percolation through a junction and filament-like resistor network. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
8Pradhan, A. K. ; Roul, B. K. ; Feng, Y. ; Wu, Y. ; Mohanty, S. ; Sahu, D. R. ; Dutta, P.
Woodbury, NY : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We report significant enhancement of magnetoresistance (MR) in melt-processed La0.67Ca0.33MnO3 (LCM) and in Ho-doped LCM samples. The LCM system exhibits surprising enhancement of metal–insulator transition (TIM) that coincides with the Curie transition temperature (Tc), TIM(approximate)Tc, illustrating the enhanced percolative transport and spin-polarization through grain boundaries. Surprisingly, 1 mol % of addition of Ho enhances Tc of ∼70 K with remarkable colossal MR. The nanoscale Ho distribution is consistent with the magnetic inhomogeneity-induced MR due to phase segregation in Ho-doped sample whereas charge-segregation picture is valid for undoped LCM. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
9Pradhan, A. K. ; Feng, Y. ; Zhao, Y. ; Koshizuka, N.
Woodbury, NY : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We report on the transport and magnetization properties of MgB2 wires fabricated by a powder-in-tube (PIT) technique. Temperature and magnetic-field-dependent resistivity displays a high conductivity and upper critical field Hc2 generally observed in dense samples. The electronic mass anisotropy γ(approximate)1.3±0.15 predicts some texturing in the wire. Our data on transition temperature TC, Hc2, and both magnetic and transport critical current density Jc indicate that MgB2 can be manufactured in a wire form using a PIT technique and required engineering Jc can be achieved on further optimization. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
10Pradhan, A. K. ; Roul, B. K. ; Wen, J. G. ; Ren, Z. F. ; Muralidhar, M. ; Dutta, P. ; Sahu, D. R. ; Mohanty, S. ; Patro, P. K.
Woodbury, NY : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We have performed magnetic and transport measurements on La0.67Ca0.33MnO3 polycrystalline and partially melted samples. The magnetization and resistance decrease as sintering temperature is increased. The insulator-to-metal transition temperature is remarkably enhanced in the partially melted sample, enabling its possible applications at room temperature. The microscopic studies in melt samples show an excellent connectivity between grains, suggesting the enhancement of percolative transport by opening new conduction channels and the disappearance of magnetic phase boundary at elevated temperature by the ordering of Mn spins blocked at the grain boundary of sintered samples. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
11Sodhi, Y. S. ; Pradhan, A. K. ; Mukhopadhyay, A. ; Pental, Deepak
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: ‘Polima’ cytoplasmic male sterility (CMS) was transferred to three different genotypes of B. napus i.e. GSL-1, ISN706 and HNS-8 by repeated backcrossing and was found to be completely stable in the nuclear background of synthetic B. napus genotype, ISN706, derived from a cross B. campestris ssp. oleifera var. brown sarson ×B. oleracea var. botrytis cv. Tusa Katki'. The BC5 and BC6 generation lines of ISN706, GSL-1 and HNS-8 with ‘Polima’ CMS were grown under a range of temperature and photo-period conditions to test their stability. No breakdown in sterility was observed in ‘Polima’ ISN706 and, therefore, this genotype can be used as a maintainer for hybrid seed production.Type of Medium: Electronic ResourceURL: -
12SRIVASTAVA, A. ; MUKHOPADHYAY, A. ; ARUMUGAM, N. ; GUPTA, V. ; VERMA, J. K. ; PENTAL, D. ; PRADHAN, A. K.
Oxford, UK : Blackwell Publishing Ltd
Published 2004Staff ViewISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: The objective of this study was to broaden the genetic base in oleiferous Brassica juncea by resynthesis, using 10 diverse parental lines of oleiferous B. rapa and two lines of B. nigra of both Indian and exotic origin. Out of 14 crosses attempted using B. rapa as the female parent, eight were successful. Embryo rescue was necessary to obtain interspecific plants. A total of 29 fertile interspecific plants were obtained after colchicine treatment. In the S2 generation, the expression of component characters in the majority of the resynthesized plants showed a negative trend. The resynthesized B. juncea lines are being maintained through repeated selfing and selection at each generation for desirable plant types. This process will continue till the progeny lines of the desirable plants achieve uniformity.Type of Medium: Electronic ResourceURL: -
13Verma, J. K. ; Sodhi, Y. S. ; Mukhopadhyay, A. ; Arumugam, N. ; Gupta, V. ; Pental, D. ; Pradhan, A. K.
Oxford, UK : Blackwell Publishing Ltd
Published 2000Staff ViewISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: ‘Polima’ cytoplasmic male sterility (CMS) was transferred from ‘Polima’ Brassica napus ‘ISN 706’to five different cultivars of Brassica campestris (‘Pusa kalyani’, ‘Pant toria’, ‘Candle’, ‘Tobin’ and ‘ATC 94211′) by repeated backcrossing. It was observed that, while ‘Polima’ CMS manifested complete and stable male sterility in the nuclear backgrounds of ‘Pusa kalyani’, ‘Pant toria’, and ‘Tobin’, the cultivars ‘Candle’ and ‘ATC 94211’possessed the restorer gene for this CMS in the heterozygous condition. An analysis of F1 and F2 generations of ‘Polima’‘Pusa kalyani’בCandle’ and ‘Polima’‘Pusa kalyani’בATC 94211’ revealed that restoration is controlled by a single dominant gene. Identification of stable maintainers and restorers of ‘Polima’ CMS could facilitate the development of hybrid varieties in B. campestris.Type of Medium: Electronic ResourceURL: -
14Sodhi, Y. S. ; Mukhopadhyay, A. ; Arumugam, N. ; Verma, J. K. ; Gupta, V. ; Pental, D. ; Pradhan, A. K.
Oxford, UK : Blackwell Publishing Ltd
Published 2002Staff ViewISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Analysis of the glucosinolate content and composition by high-pressure liquid chromatography indicated that varieties of Brassica juncea bred and grown in India have a high glucosinolate content characterized by the presence of 2-propenyl (allyl) and 3-butenyl as the major and 4-pentenyl as the minor fractions. In contrast, the B. juncea germplasm from other countries is characterized by the presence of 2-propenyl as the major glucosinolate fraction, trace amounts of 3-butenyl and a total lack of the 4-pentenyl types. In order to transfer the low glucosinolate trait to Indian B. juncea, the inheritance of total glucosinolates was investigated using doubled haploid (DH) populations derived from F1 (DH1) and BC1 (BC1DH) of a cross between ‘Varuna’ (the most widely cultivated high glucosinolate variety of India) and ‘Heera’ (a non-allyl type low glucosinolate line). A total of 752 DH1 and 1263 BC1DH gave rise to seven and 11 low glucosinolate (containing less than 18 μmol/g seed) individuals, respectively. On the basis of the frequency of the low glucosinolate individuals, the total glucosinolate was found to be under the control of seven genes. There was presence of both allyl and non-allyl types in DH1 and BC1DH low-glucosinolate individuals and absence of 3-butenyl glucosinolate in some of the BC1DH low glucosinolate individuals, indicating segregation for these fractions in the population. The size of the segregating DH population proved to be crucial for precise determination of the number of genes controlling the trait. Because of the large number of genes involved, incorporation of low glucosinolate trait in Indian B. juncea should be approached through doubled haploid (DH) breeding.Type of Medium: Electronic ResourceURL: -
15Arumugam, N. ; Mukhopadhyay, A. ; Gupta, V. ; Sodhi, Y. S. ; Verma, J. K. ; Pental, D. ; Pradhan, A. K.
Oxford, UK : Blackwell Publishing Ltd
Published 2002Staff ViewISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Brassica carinata (BBCC), a potential oilseed crop for dry land agriculture, is sensitive to high temperatures during germination and early stages of growth, which thereby restricts the possibility of using the residual soil moisture available after the rainy season for its cultivation. To overcome this problem, a three-genome hybrid, RCBB, was synthesized using Raphanus sativus (RR) and Brassica oleracea (CC) as donor sources for the desired heat tolerance. Protoplasts of RC hybrids obtained through sexual crosses between R. sativus (female) and B. oleracea (male) were fused with protoplasts of Brassica nigra (BB) to produce RCBB somatic hybrids. The hybrid colonies regenerated with an average frequency of 7.6%. Twelve out of 36 hybrids grown to maturity were characterized for their nuclear and organelle genomes. While all the hybrids showed the presence of B. nigra chloroplasts, 10 of the hybrids showed B. nigra-specific mitochondria and two had Raphanus-spedfic mitochondria. The somatic hybrids could be backcrossed to B. carinata.Type of Medium: Electronic ResourceURL: -
16Sodhi, Y. S. ; Pradhan, A. K. ; Verma, J. K. ; Arumugam, N. ; Mukhopadhyay, A. ; Pental, D.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Eighteen genotypes of Brassica napus were crossed to a cytoplasmic male sterile (CMS) line of B. napus BO 15 carrying B. tournefortii cytoplasm (‘tour’ cytoplasm). Fourteen genotypes were found to be stable maintainers of the ‘tour’ CMS. Of the remaining four genotypes, GSL-1 and ‘Asahi-natane’ were found to be heterozygous and ‘Mangun’ and ‘Yudal’ were homozygous for the restorer gene. Analysis of the F1 and F2 progenies of (CMS) BO 15 בMangun’ and (CMS) BO 15 בYudal’ showed that fertility restoration is controlled by a single dominant gene. The availability of a number of stable maintainer lines and the simple inheritance pattern of fertility restorer gene makes ‘tour’ CMS a useful system for hybrid seed production in rapeseed.Type of Medium: Electronic ResourceURL: -
17Pradhan, A. C. ; Chawla, T. N. ; Samuel, K. C. ; Pradhan, Mrs. S.
Oxford, UK : Blackwell Publishing Ltd
Published 1971Staff ViewISSN: 1600-0765Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The purpose of present study was to determine the relationship between periodontal disease and blood groups with special reference to secretor status. 600 medical students constituted the study group and three sets of control were taken in parallel. First set was of 6000 blood donors for normal distribution of blood groups. Second set consisted of 200 cases selected on random basis from patients attending the Dental Out-patient Department for blood groups and secretor status. Third set comprised of 100 cases with grade 0 periodontal involvement selected from the study group. The periodontal scoring was done in each case by Ramfjord's technique and the study group cases were divided into four grades - 0, 1, II, and III. Blood grouping was done by slide and tube method and secretor status was tested by haemagglutination method of Weiner as modified by Roy and Chatterji. Statistically significant relationship was found between periodontal disease and blood groups but none with secretor status. This relationship points towards a possible genetic basis for etiopathogenesis of periodontal disease which should be explored further by conducting extensive studies.It is a pleasure to acknowledge Dr. K. K. Kapoor, Reader, Division of Periodontics, Dental College and Hospital, Lucknow, for his valuable guidance and fruitful discussions in the planning and accomplishment of the present work. Our grateful appreciation is also due to Dr. Mrs. V. L. Lahiri, Reader in Pathology. G. S. V. M. Medical College. Kanpur, for her valuable suggestions and constructive criticism during the elaboration of the manuscript.Type of Medium: Electronic ResourceURL: -
18Cebra, D.A. ; Benenson, W. ; Chen, Y. ; Kashy, E. ; Pradhan, A. ; Vander Molen, A. ; Westfall, G.D. ; Wilson, W.K. ; Morrissey, D.J. ; Korteling, R. ; Helmer, R.L. ; Tickle, R.S.
Amsterdam : ElsevierStaff ViewISSN: 0370-2693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Pradhan, A. R. ; Viswanadham, N. ; Suresh, S. ; Gupta, O. P. ; Ray, N. ; Muralidhar, G. ; Shanker, Uma ; Prasada Rao, T. S. R.
Springer
Published 1994Staff ViewISSN: 1572-879XKeywords: n-heptane aromatisation ; ZSM-5 ; non-templatedSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyNotes: Abstract ZSM-5 was prepared without the aid of an organic template. Effect of synthesis parameters on its catalytic activity in aromatisation ofn-heptane are discussed. Addition of seed material increased the crystallinity of the ZSM-5 phase. The catalytic activity was comparable with a sample prepared using an organic template. Formation of higher amount of C9– aromatics was observed over the non-templated zeolite.Type of Medium: Electronic ResourceURL: -
20Foster, V. J. ; Keenan, F. P. ; Reid, R. H. G. ; Doyle, J. G. ; Zhang, H. L. ; Pradhan, A. K. ; Widing, K. G.
Springer
Published 1997Staff ViewISSN: 1573-093XSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract Recent calculations of Mgviii electron and proton impact excitations rates are used to derive theoretical electron temperature (T e)- and density (N e)-sensitive emission line ratios involving transitions in the 315–782 Å wavelength range. Some of these ratios are presented in the form of ratio–ratio diagrams, which should in principle allow both N e and T e to be deduced. These results are compared with solar observational data from Skylab, but agreement between theory and observation is very poor, probably due to blending.Type of Medium: Electronic ResourceURL: