Search Results - (Author, Cooperation:A. Nakajima)
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1Latest Papers from Table of Contents or Articles in PressT. Olszak ; J. F. Neves ; C. M. Dowds ; K. Baker ; J. Glickman ; N. O. Davidson ; C. S. Lin ; C. Jobin ; S. Brand ; K. Sotlar ; K. Wada ; K. Katayama ; A. Nakajima ; H. Mizuguchi ; K. Kawasaki ; K. Nagata ; W. Muller ; S. B. Snapper ; S. Schreiber ; A. Kaser ; S. Zeissig ; R. S. Blumberg
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-04-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antigens, CD1d/*immunology ; Carrier Proteins/metabolism ; Colitis/immunology/pathology ; Disease Models, Animal ; Epithelial Cells/*immunology/metabolism ; Female ; HSP110 Heat-Shock Proteins/genetics/metabolism ; Humans ; Immunity, Mucosal/*immunology ; Inflammation/immunology/pathology ; Inflammatory Bowel Diseases/immunology/pathology ; Interleukin-10/genetics/*immunology ; Intestinal Mucosa/*cytology/*immunology ; Male ; Mice ; Natural Killer T-Cells/immunology/metabolism ; Oxazolone ; STAT3 Transcription Factor/metabolismPublished by: -
2Articles: DFG German National LicensesMoriguchi, M. ; Terai, C. ; Koseki, Y. ; Uesato, M. ; Nakajima, A. ; Inada, S. ; Nishinarita, M. ; Uchida, S. ; Kim, S.Y. ; Chen, C.-L. ; Kamatani, N.
Springer
Published 1999Staff ViewISSN: 1432-1203Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract. To examine whether polymorphism at the SAA loci is associated with the development of amyloid protein A (AA)-amyloidosis, we determined the genotypes at the SAA1 and SAA2 loci in 43 AA-amyloidosis patients (amyloidosis population) and 77 patients with rheumatoid arthritis (RA) who had been ill for less than 5 years (early RA population). We also compared the frequencies of the genotypes at the SAA1 locus among 90 Korean, 95 Taiwanese, and 103 Japanese healthy subjects. The frequencies of the γ/γ genotype and γ alleles at the SAA1 locus were significantly higher in the amyloidosis population than in the early RA population (34.9% versus 7.8%, and 58.1% versus 33.8%, χ2 test P=0.0001). The frequencies of the γ allele at the SAA1 locus in Koreans, Taiwanese, and Japanese were 41.6%, 35.6%, and 37.4%, respectively. The length of the latent period of AA-amyloidosis was significantly longer in the patients with smaller numbers of the γ allele at the SAA1 locus (Spearman's correlation coefficient: –0.42, P〈0.05). On the other hand, the mean C-reactive protein (CRP) level during 2 years prior to the diagnosis of AA-amyloidosis was significantly higher in the patients with larger numbers of the γ allele at the SAA1 locus (Spearman's correlation coefficient: 0.34, P〈0.05). No significant association was found between amyloidosis and polymorphism at the SAA2 locus. We postulate that the allele SAA1 γ renders an RA patient susceptible to amyloidosis, possibly by affecting the severity of inflammation in RA.Type of Medium: Electronic ResourceURL: -
3Latest Papers from Table of Contents or Articles in PressNakajima, A., Vogelzang, A., Maruya, M., Miyajima, M., Murata, M., Son, A., Kuwahara, T., Tsuruyama, T., Yamada, S., Matsuura, M., Nakase, H., Peterson, D. A., Fagarasan, S., Suzuki, K.
Rockefeller University Press
Published 2018Staff ViewPublication Date: 2018-08-07Publisher: Rockefeller University PressPrint ISSN: 0022-1007Electronic ISSN: 1540-9538Topics: MedicineKeywords: Mucosal ImmunologyPublished by: -
4Articles: DFG German National LicensesNakajima, A. ; Sugita, Y. ; Kawamura, K. ; Tomita, H. ; Yokoyama, N.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: We report a simple technique for fabricating a layer of isolated Si quantum dots on SiO2 glass substrates. This technique uses conventional low-pressure chemical-vapor deposition for an extremely short deposition time in the early stage of poly-Si film growth. The layer after a deposition time of 60 s has isolated Si nanocrystals 5–20 nm in diameter and 2–10 nm in height. The measurements of optical absorption coefficient α show that the absorption edge for Si nanocrystals shifts to higher energies compared to that of bulk Si, indicating a widening of the energy gap caused by quantum size effects. The linear relationship (αhν)1/2 against hν suggests that the Si nanocrystal, whose diameter is as small as 10 nm, basically maintains the properties of an indirect band-gap semiconductor. Special attention must be paid to the Brownian migration of Si nanocrystals for fabricating Si quantum dots. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesNakajima, A. ; Ohshima, Y. ; Itakura, T. ; Goto, Y.
Woodbury, NY : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We examined the microstructure of luminescent porous silicon by cross-sectional high-resolution transmission electron microscopy and found a threadlike structure consisting of Si microcrystals. We also found Si microcrystals with sizes ranging about 3–20 nm randomly distributed throughout the porous silicon.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesTakada, J. ; Awaji, H. ; Koshioka, M. ; Nakajima, A. ; Nevin, W. A.
Woodbury, NY : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: By utilizing copper phthalocyanine (CuPc) and TiOx, we report the fabrication of organic–inorganic heteromultilayer structures as a new concept of optoelectronic material. These are based on an anticipated model where charge carrier photogeneration occurs in the CuPc layers, while the TiOx layers have the role of transportation of electrons in-plane after charge separation at the interfaces. Atomic force microscopy has confirmed the formation of layered structures for samples with an artificial period of more than 50 A(ring). The multilayers are found to exhibit 40 times higher photoconductivity than a CuPc single layer.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesNakajima, A. ; Itakura, T. ; Watanabe, S. ; Nakayama, N.
Woodbury, NY : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We examined the change in photoluminescence spectra of porous Si when it is oxidized then deoxidized chemically. After both steps, photoluminescence shifted to higher frequencies and increased in intensity. These shifts to higher frequencies indicate the photoluminescence is a result of the quantum size effect. Moreover, the increase in photoluminescence intensity after oxidation suggests that termination by hydrogen on the porous Si surface does not always play a key role in the photoluminescence mechanism.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesMiyake, K. ; Ueki, N. ; Suzuki, K. ; Shinji, Y. ; Kusunoki, M. ; Hiratsuka, T. ; Nishigaki, H. ; Tatsuguchi, A. ; Futagami, S. ; Wada, K. ; Tsukui, T. ; Nakajima, A. ; Yoshino, S. ; Sakamoto, C.
Oxford, UK : Blackwell Publishing Ltd
Published 2005Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background : There is a lack of evidence for the efficacy of preventive medications for peptic ulcers (PUs) among long-term users of non-steroidal anti-inflammatory drugs (NSAIDs) in Japan.Aim : To estimate the preventive effect by normal dose, not high-dose histamine-H2 receptor antagonists (H2RA) for NSAID-induced ulcers.Methods : We designed two different studies to assess the efficacy of anti-ulcer agents in rheumatoid arthritis (RA) in patients treated over a long term with NSAIDs. An investigative survey divided patients into those not taking anti-ulcer agents (non-medication group); those taking mucosal protective agents (mucosal protectant group), H2RA (H2RA group), proton pump inhibitors (PPI group), or a prostaglandin E1 analog (PG) (PG group). The second study compared prospectively the preventive effects of either famotidine 20 mg bd (famotidine group) or lansoprazole 15 mg daily (lansoprazole group) in patients with PU scars.Results : The prevalence of PU in the H2RA group was significantly lower compared to the mucosal protectant group (P 〈 0.05), and the mucosal protectant group was not significantly different to the non-medication group. The prospective study revealed that the PU onset rate of the famotidine group was 8% (1/13), and lansoprazole group was 15% (2/13), indicating no significant differences between the two.Conclusions : In Japan, normal-dose H2RA is expected to be a new PU preventive treatment strategy in patients requiring long-term NSAID therapy.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1359-0197Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesSugihara, M. ; Fujisawa, N. ; Yamamoto, T. ; Nishio, S. ; Okazaki, T. ; Iida, H. ; Yoshizu, T. ; Nakajima, A.
Amsterdam : ElsevierStaff ViewISSN: 0920-3796Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0022-2852Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 0584-8539Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 0584-8539Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: