Search Results - (Author, Cooperation:A. Murthy)

2018-01-12

BMJ Publishing

2044-6055

Medicine

Open access, Infectious diseases

2012-01-17

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Computer Science

Medicine

Natural Sciences in General

Physics

ADAM Proteins/genetics/*metabolism ; Amino Acid Sequence ; Animals ; B-Lymphocytes/immunology/metabolism ; Base Sequence ; Carrier Proteins/chemistry/genetics/*metabolism ; Cell Line ; Cell Membrane/metabolism ; Gene Deletion ; *Immunity, Innate ; Lipopolysaccharides/*immunology ; Listeria monocytogenes/immunology/physiology ; Listeriosis/*immunology/metabolism/microbiology/pathology ; Macrophages/immunology/metabolism ; Macrophages, Peritoneal/immunology/metabolism/microbiology ; Mice ; Molecular Sequence Data ; Protein Transport ; Shock, Septic/*immunology/metabolism ; Spleen/cytology ; Tumor Necrosis Factor-alpha/blood/genetics/*metabolism

2018-09-18

American Physical Society (APS)

0031-9007

1079-7114

Physics

General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.

2014-02-21

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Amino Acid Motifs ; Animals ; Autophagy/genetics ; Carrier Proteins/chemistry/*genetics/*metabolism ; Caspase 3/deficiency/genetics/*metabolism ; Cell Line ; Cells, Cultured ; Crohn Disease/*genetics/pathology ; Cytokines/immunology ; Enzyme Activation ; Female ; Food Deprivation ; Humans ; Macrophages/immunology/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mutagenesis, Site-Directed ; Polymorphism, Single Nucleotide/*genetics ; *Proteolysis ; Stress, Physiological ; Yersinia enterocolitica/immunology

1365-2478

Blackwell Publishing Journal Backfiles 1879-2005

Geosciences

Physics

The interpretation of total field anomalies becomes somewhat complicated, especially when an arbitrarily magnetized spherical ore mass happens to be the causative body. Even though some attempts have been made to analyze total field anomaly maps, they are often too complicated and their underlying assumptions in respect of permanent and induced components of magnetism are far from realistic. In this note, an attempt has been made to show that vertical magnetic anomalies are capable of yielding interpretation with ease and precision as far as magnetized spheres are concerned. An empirical method has been outlined for computing the magnetization inclination in the plane of the profile using the measured distances between principal maximum, principal minimum, and zero anomaly positions on a magnetic anomaly profile.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

Previous studies have shown that high coercivities can be achieved in cast Nd–Fe–C alloys through an annealing heat treatment at 900 °C, which causes a peritectoidal transformation from Nd2Fe17Cx to Nd2Fe14Cx. We have studied the characteristics of this transformation in cast Nd15DyFe75(C,B)9 alloys. Optimum coercivities were obtained by annealing for 6 h at 900 °C. A highly faulted carbide phase was identified in samples annealed for 5 min at 900 °C. From electron diffraction investigations, this phase was identified to be hexagonal with lattice parameters, a=0.48 nm and c=0.81 nm. The development of coercivity in the various stages of transformation is related to the crystal structure and microstructure developed in the transformation. The presence of α-Fe in samples with increased Fe content leads to reduced coercivities. © 1996 American Institute of Physics.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

Coercivity optimization studies were done on melt-spun nanocomposite Nd4R2Fe87−xNbTxB6 (R=Nd,Y,Dy; T=Ag,Cu) isotropic ribbon samples. The maximum attainable coercivities, after adjusting the annealing time, were found to be very sensitive to the annealing temperatures. The optimum magnetic properties [HC=3.9 kOe, (BH)max=10 MGOe] were obtained by annealing at 750–775 °C for a few minutes. Optimization by flash annealing gave similar results. Microstructural studies show that the grain size is greater than the theoretically predicted grain size for optimum coupling between the hard and the soft phase. With the annealing conditions used, Nd4Dy2Fe87NbB6 samples gave moderate coercivities and in Nd4Y2Fe87NbB6 samples the coercivity was reduced more than the expected reduction in the anisotropy field due to the presence of Y. © 1996 American Institute of Physics.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

The magnetic, structural and microstructural properties of sputtered Fe thin films and Fe(backward-slash)Fe–O bilayers were studied as a function of the Fe layer thickness, the type of the Fe oxide and the substrate used. Two different ways to prepare the oxide layers were used; postdeposition oxidation and reactive sputtering. Postdeposition oxidation produced films with mixed Fe–oxides (FeO, Fe3O4, Fe2O3); however reactive sputtering led to bilayers with controlled stoichiometry, Fe(backward-slash)FeO, Fe(backward-slash)Fe3O4, and Fe(backward-slash)FE2O3, respectively. The coercivity of both the Fe films and fE(backward-slash)Fe–O bilayers, deposited on substrates with or without Cr buffer layer, was found to increase with decreasing Fe film thickness. The coercivity of the samples deposited on a Ag buffer layer was much lower and did not change substantially with the Fe film thickness. The presence of the Fe–oxide layer led to a large increase of coercivity. This is attributed to the higher anisotropy of the oxide and to exchange coupling of Fe–oxide with the softer Fe layer. © 1996 American Institute of Physics.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

The structural and magnetic properties of sputtered Fe/Fe-O films were studied by x-ray photoelectron spectroscopy (XPS), Rutherford backscattering spectroscopy, transmission electron microscopy, and superconducting quantum interference device. XPS studies showed the presence of FeO and Fe2O3 on the surface of as-made samples. Microstructure studies showed a uniform nanostructure with the grain size in the range of 50–150 A(ring) with smaller grains corresponding to thinner films. The coercivity at 10 K was found to increase substantially with decreasing film thickness below 60 A(ring). A high Hc (2.7 kOe) was observed in samples with a thickness about 20 A(ring). Magnetization curves showed a planar anisotropy with a shifted hysteresis loop characteristic of an exchange anisotropy between the Fe and Fe-O coating. The coercivity was found to drop steeply with increasing temperature. This may be attributed to the superparamagnetic behavior of the Fe-O surface layer.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

The Fe–Zr–B system has been shown to exhibit superior soft magnetic properties in melt-spun ribbons. These ribbons with composition Fe87Zr7Cu3B3 had very low coercivity (0.02 Oe) and high magnetization (190 emu/g) after crystallization at 540 °C from the amorphous state. We have recently extended these studies to thin films with similar composition. These films were prepared by dc magnetron sputtering from a solid alloy target. Transmission electron microscopy and differential scanning calorimetry were used to study the evolution of the microstructure upon annealing. Magnetic measurements were taken with a hysteresigraph. Unlike the as-spun ribbon samples, the as-sputtered films showed 10 nm crystallities. Selected area diffraction patterns indicated a two phase microstructure, with the bcc phase which gave rise to the soft magnetic properties in the ribbons, coexisting with a second phase leading to degraded soft magnetic properties (Hc=20 Oe and Ms=150 emu/g). Subsequent annealing of the thin film samples enhanced the formation of the second phase and further degraded the soft magnetic properties. Work is currently underway to determine a means of suppressing the formation of the secondary phase while preserving the phase with superior soft properties. © 1996 American Institute of Physics.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

The structural and magnetotransport properties of (FeyCo1−y)100−xAgx films were studied as a function of composition. Giant magnetoresistance (GMR) values were measured in these granular films, with the best GMR obtained for the composition (Fe0.33Co0.67)27Ag73, with values of 29% at 30 K and 11.7% at 300 K. XRD and TEM results have shown a fcc crystal structure with a relatively homogeneous microstructure. Magnetic data for the samples with the best GMR indicate a superparamagnetic behavior. The narrow peak in thermomagnetic data and low blocking temperature suggest a small and uniform size distribution of magnetic granules. A summary of the electrical transport properties is presented, in relation to the structural, microstructural, and magnetic properties.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

Previous studies have shown that large coercivities, exceeding 2 kOe, can be obtained in Fe-based ceramic granular films. The coercivities were also found to be sensitive to the type of matrix material used, being higher in the SiO2 matrix. In this study the hysteresis behavior of FeX(SiO2)1−X granular films was studied as a function of the preparation technique. The films were prepared by dc magnetron sputtering over the composition range of xv=0.1–0.9 volume fraction of Fe. Tandem deposition both with and without titanium sublimation, and deposition from a composite target were used in preparing the films, which resulted in different oxygen environments. Coercivity measurements were found to be strongly composition dependent, with maximum values up to 700 Oe at xv≈0.5 of Fe, for all sets of samples. Typical granular structure was observed, with grain size in the range of 5–20 nm, with the smaller size obtained from composite targets. X-ray diffraction and selected area diffraction showed a structure of a-Fe (bcc). Thermomagnetic curves showed a peak which can be associated with the onset of superparamagnetism. By varying the deposition method and the oxygen environment, we were able to switch from a relatively magnetically hard sample (Hc∼500 Oe) to a soft sample (Hc∼20 Oe). Mossbauer data are being analyzed to determine the presence of any oxides, their magnetic state and their effect on hysteresis. © 1996 American Institute of Physics.

Electronic Resource

1365-246X

Blackwell Publishing Journal Backfiles 1879-2005

Geosciences

Deep seismic sounding data were acquired in the West Bengal basin, India, along two profiles: (i) Bishnupur–Palashi–Kandi, along a line about 227 km long in the north–south direction and (ii) Taki–Arambagh, along a line about 120 km long in the east–west direction. Seismic refraction and wide-angle reflection data were recorded by continuous profiling using two 60-channel digital seismic units (DFS-V) with an 80 m geophone group interval and 4 ms sampling rate. These data were interpreted in order to delineate the basement configuration. The 2-D models of the seismic data both indicate a five-layer velocity structure above the Archaean crystalline basement (5.9–6.2 km s−1). A low-velocity layer (4.0 km s−1) is inferred immediately above the basement in the shelf region of the basin corresponding to the Gondwana sediments (Upper Carboniferous to Lower Triassic) below the Rajmahal Traps (Upper Jurassic to Lower Cretaceous) of 4.6 to 4.8 km s−1 velocity, which is also confirmed from the nearby well data. The results along the Taki–Arambagh profile and the drilling results at the Jaguli (J-1) well are used to investigate whether Gondwana sediments and the Rajmahal Traps exist in the deep part of the Bengal basin. An additional layer of velocity 5.2–5.3 km s−1, delineated in the Palashi–Kandi profile overlying the basement, may correspond to the Singhbhum group of rocks of the Proterozoic.A structural contour map of the basement prepared from the present results indicates a south-easterly dip of the basement in general. The depth of the basement on the stable shelf of the basin gently increases to about 8 km and dips steeply, plunging to a maximum depth of 14 km in the deep basin. No structural high that can be related to the ‘Calcutta gravity high’ is found in the basement around the Hooghly River.

Electronic Resource

1365-2036

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Background: Peptone meal-stimulated gastric acid output is considered to be a reliable means to evaluate drug-mediated inhibition of stimulated gastric acid output, an important measure of the efficacy of the agents — such as proton pump inhibitors — used to treat acid-related disorders.Aim: To compare the initial and overall inhibitory effects on peptone meal-stimulated gastric acid secretion of rabeprazole and omeprazole, 20 mg, in Helicobacter pylori-negative subjects on the first and eighth days of treatment.Methods: Healthy volunteers (n = 27) were randomized in a single-centre, double-blind, double-dummy, 2 × 2 cross-over study. Subjects received an oral dose of rabeprazole or omeprazole, 20 mg once daily, for 8 days. After a 2–4-week washout period, subjects were crossed over to receive the other medication for 8 days. Peptone meal-stimulated gastric acid secretion was measured at hours 11 and 23 at baseline and on days 1 and 8 of treatment.Results: On days 1 and 8, rabeprazole demonstrated a significantly greater inhibition of peptone meal-stimulated gastric acid secretion compared with omeprazole at all time points (P 〈 0.03). Median values of steady-state inhibition on day 1 were statistically significant at hour 23 (rabeprazole 100% vs. omeprazole 74%, P 〈 0.02).Conclusions: Rabeprazole, 20 mg, demonstrated superior control of peptone meal-stimulated gastric acid secretion compared with omeprazole, 20 mg, after the first dose and after the eighth daily dose. Rabeprazole achieved a more rapid onset of acid inhibition and a greater steady-state reduction in peptone meal-stimulated gastric acid secretion.

Electronic Resource

1365-2036

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

In numerous clinical trials, proton pump inhibitors have demonstrated potent acid suppression and healing of erosive oesophagitis, as well as successful symptom relief for the entire spectrum of gastro-oesophageal reflux disease.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:The `Future of Acid Suppression Therapy' (FAST) trial evaluated, in actual clinical practice, the timing of symptom relief, changes in symptom severity, health-related quality of life and safety in endoscopically confirmed erosive gastro-oesophageal reflux disease treated with rabeprazole.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:This open-label, multicentre study enrolled 2579 patients to receive rabeprazole treatment using 20 mg once daily for 8 weeks. Between two clinical visits (at enrolment and week 8), patients used an interactive voice response system to rate gastro-oesophageal reflux disease symptoms. Subgroup analyses of efficacy were conducted for gender, age, Hetzel–Dent grade, presence of Barrett's oesophagus and for patients reporting previously ineffective symptom relief with omeprazole or lansoprazole.〈section xml:id="abs1-4"〉〈title type="main"〉Results:On day 1, rabeprazole significantly decreased daytime and night-time heartburn severity, regurgitation and belching. Complete relief of daytime and night-time heartburn was achieved in 64.0% and 69.2% of symptomatic patients, respectively, on day 1, and in 81.1% and 85.7% of patients, respectively, on day 7. Patients with moderate or severe heartburn symptoms at baseline achieved an even greater degree of satisfactory symptom relief (none or mild) from day 1 onwards. The median time to satisfactory heartburn relief was 2 days. Subgroup analyses showed no consistent differences in efficacy compared to the overall population treated. Health-related quality of life in patients was significantly lower than that of the US general population and improved significantly after 8 weeks of rabeprazole therapy. Rabeprazole was well tolerated, with headache as the most common adverse event, reported by less than 2% of the study population.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:In this large, open-label trial, rabeprazole rapidly and effectively relieved gastro-oesophageal reflux disease symptoms in most patients with erosive oesophagitis. Substantial symptom relief was noted on day 1; improvement continued over the first week and at week 4. By week 8, the health-related quality of life had also improved vs. baseline.

Electronic Resource

1476-4687

Nature Archives 1869 - 2009

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

[Auszug] Other oxy-salts are also found to give off a limited supply of oxygen for the burning of sulphur in vacuum. For example, when a mixture of uranium nitrate and excess of powdered sulphur is heated in vacuum, oxides of nitrogen and disulphur monoxide are evolved which would condense in a trap cooled ...

Electronic Resource

0040-4020

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Electronic Resource

0022-460X

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Physics

Electronic Resource

0167-5087

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Energy, Environment Protection, Nuclear Power Engineering

Physics

Electronic Resource

1436-5073

Springer Online Journal Archives 1860-2000

Chemistry and Pharmacology

Zusammenfassung Fein verteiltes Selen und Tellur werden in saurem Medium von konzentrierter Chloramin-T-Lösung zu Selensäure bzw.o-Tellursäure oxydiert. Auf der Grundlage dieser Reaktion wurde eine Bestimmungsmethode ausgearbeitet, deren Genauigkeit unter 1% liegt.

Summary Finely divided selenium and tellurium undergo oxidation to selenic and orthotelluric acids by a concentrated solution of chloramine-T in acid medium. An analytical procedure (accurate to 〈1 %) has been developed based on this reaction.

Electronic Resource