Search Results - (Author, Cooperation:A. Melnick)
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1Evans, B. J., Tosi, A. J., Zeng, K., Dushoff, J., Corvelo, A., Melnick, D. J.
Royal Society
Published 2018Staff ViewPublication Date: 2018-06-14Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: genetics, bioinformatics, evolutionPublished by: -
2L. Wang ; A. Gural ; X. J. Sun ; X. Zhao ; F. Perna ; G. Huang ; M. A. Hatlen ; L. Vu ; F. Liu ; H. Xu ; T. Asai ; T. Deblasio ; S. Menendez ; F. Voza ; Y. Jiang ; P. A. Cole ; J. Zhang ; A. Melnick ; R. G. Roeder ; S. D. Nimer
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-07-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Acetylation ; Animals ; Cell Line ; Cell Line, Tumor ; *Cell Transformation, Neoplastic ; Core Binding Factor Alpha 2 Subunit/chemistry/*metabolism ; E1A-Associated p300 Protein/antagonists & inhibitors/*metabolism ; Fetal Blood/cytology ; Gene Expression Profiling ; Hematopoietic Stem Cells/*cytology/physiology ; Humans ; Leukemia, Myeloid, Acute/*metabolism/pathology ; Lysine/*metabolism ; Mice ; Mice, Inbred C57BL ; Mutant Proteins/metabolism ; Oncogene Proteins, Fusion/chemistry/*metabolism ; Preleukemia/metabolism/pathology ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Processing, Post-Translational ; Transcriptional Activation ; Tumor Cells, CulturedPublished by: -
3C. Duy ; C. Hurtz ; S. Shojaee ; L. Cerchietti ; H. Geng ; S. Swaminathan ; L. Klemm ; S. M. Kweon ; R. Nahar ; M. Braig ; E. Park ; Y. M. Kim ; W. K. Hofmann ; S. Herzog ; H. Jumaa ; H. P. Koeffler ; J. J. Yu ; N. Heisterkamp ; T. G. Graeber ; H. Wu ; B. H. Ye ; A. Melnick ; M. Muschen
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-05-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: ADP-Ribosylation Factor 1/metabolism ; Animals ; Cell Survival/drug effects ; DNA-Binding Proteins/biosynthesis/deficiency/genetics/*metabolism ; *Drug Resistance, Neoplasm ; Fusion Proteins, bcr-abl/*antagonists & inhibitors ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug ; therapy/genetics/metabolism/*pathology ; Protein Kinase Inhibitors/*pharmacology/therapeutic use ; Transcription, Genetic ; Tumor Suppressor Protein p53/metabolismPublished by: -
4C. Lu ; P. S. Ward ; G. S. Kapoor ; D. Rohle ; S. Turcan ; O. Abdel-Wahab ; C. R. Edwards ; R. Khanin ; M. E. Figueroa ; A. Melnick ; K. E. Wellen ; D. M. O'Rourke ; S. L. Berger ; T. A. Chan ; R. L. Levine ; I. K. Mellinghoff ; C. B. Thompson
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-02-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 3T3-L1 Cells ; Adipocytes/cytology/drug effects/metabolism ; Animals ; Astrocytes/cytology/drug effects ; Cell Differentiation/drug effects/*genetics ; Cell Line, Tumor ; Cell Lineage/genetics ; DNA Methylation/drug effects ; Enzyme Induction/drug effects ; Gene Expression Regulation/drug effects ; Glioma/enzymology/genetics/pathology ; Glutarates/metabolism/pharmacology ; HEK293 Cells ; Histones/*metabolism ; Humans ; Isocitrate Dehydrogenase/antagonists & inhibitors/*genetics/metabolism ; Jumonji Domain-Containing Histone Demethylases/antagonists & ; inhibitors/deficiency/genetics/metabolism ; Methylation/drug effects ; Mice ; Mutation/*genetics ; Neural Stem Cells/metabolism ; Promoter Regions, Genetic/geneticsPublished by: -
5Z. Chen ; S. Shojaee ; M. Buchner ; H. Geng ; J. W. Lee ; L. Klemm ; B. Titz ; T. G. Graeber ; E. Park ; Y. X. Tan ; A. Satterthwaite ; E. Paietta ; S. P. Hunger ; C. L. Willman ; A. Melnick ; M. L. Loh ; J. U. Jung ; J. E. Coligan ; S. Bolland ; T. W. Mak ; A. Limnander ; H. Jumaa ; M. Reth ; A. Weiss ; C. A. Lowell ; M. Muschen
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-03-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Motifs/genetics ; Animals ; Antigens, CD/metabolism ; Antigens, CD31/metabolism ; B-Lymphocytes/drug effects/*metabolism/*pathology ; Cell Death/drug effects ; Cell Line, Tumor ; Cell Transformation, Neoplastic ; Disease Models, Animal ; Drug Resistance, Neoplasm/drug effects ; Enzyme Activation/drug effects ; Female ; Fusion Proteins, bcr-abl/genetics ; Gene Deletion ; Humans ; Intracellular Signaling Peptides and Proteins/agonists/metabolism ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Phosphoric Monoester Hydrolases/antagonists & inhibitors/metabolism ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug ; therapy/genetics/*metabolism/*pathology ; Precursor Cells, B-Lymphoid/drug effects/metabolism/pathology ; Protein Tyrosine Phosphatase, Non-Receptor Type 6/deficiency/genetics/metabolism ; Protein-Tyrosine Kinases/metabolism ; Receptors, Antigen, B-Cell/deficiency/genetics/metabolism ; Receptors, Immunologic/genetics/metabolism ; *Signal Transduction/drug effects ; Tyrosine/metabolism ; Xenograft Model Antitumor AssaysPublished by: -
6X. J. Sun ; Z. Wang ; L. Wang ; Y. Jiang ; N. Kost ; T. D. Soong ; W. Y. Chen ; Z. Tang ; T. Nakadai ; O. Elemento ; W. Fischle ; A. Melnick ; D. J. Patel ; S. D. Nimer ; R. G. Roeder
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-07-03Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Motifs ; Amino Acid Sequence ; Animals ; Binding Sites ; Cell Division ; Cell Line, Tumor ; *Cell Transformation, Neoplastic/genetics ; Core Binding Factor Alpha 2 Subunit/chemistry/*metabolism ; Hematopoietic Stem Cells/cytology/metabolism/pathology ; Humans ; Leukemia, Myeloid, Acute/genetics/*metabolism/*pathology ; Mice ; Models, Molecular ; Molecular Sequence Data ; Multiprotein Complexes/chemistry/*metabolism ; Oncogene Proteins, Fusion/chemistry/*metabolism ; Point Mutation ; Protein Binding ; Protein Multimerization ; Protein Stability ; Protein Structure, Tertiary ; Transcription Factors/*metabolismPublished by: -
7Z. Chen ; S. Shojaee ; M. Buchner ; H. Geng ; J. W. Lee ; L. Klemm ; B. Titz ; T. G. Graeber ; E. Park ; Y. X. Tan ; A. Satterthwaite ; E. Paietta ; S. P. Hunger ; C. L. Willman ; A. Melnick ; M. L. Loh ; J. U. Jung ; J. E. Coligan ; S. Bolland ; T. W. Mak ; A. Limnander ; H. Jumaa ; M. Reth ; A. Weiss ; C. A. Lowell ; M. Muschen
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
8M. Sasaki ; C. B. Knobbe ; J. C. Munger ; E. F. Lind ; D. Brenner ; A. Brustle ; I. S. Harris ; R. Holmes ; A. Wakeham ; J. Haight ; A. You-Ten ; W. Y. Li ; S. Schalm ; S. M. Su ; C. Virtanen ; G. Reifenberger ; P. S. Ohashi ; D. L. Barber ; M. E. Figueroa ; A. Melnick ; J. C. Zuniga-Pflucker ; T. W. Mak
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-06Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aging ; Animals ; Bone Marrow/pathology ; Cell Lineage ; CpG Islands/genetics ; DNA Methylation ; Disease Models, Animal ; Epigenesis, Genetic/*genetics ; Female ; Gene Knock-In Techniques ; Glioma/pathology ; Hematopoiesis ; Hematopoietic Stem Cells/*cytology/metabolism ; Histones/metabolism ; Humans ; Isocitrate Dehydrogenase/*genetics/*metabolism ; Leukemia, Myeloid, Acute/genetics ; Male ; Mice ; Mutant Proteins/genetics/*metabolism ; Mutation/*genetics ; Myeloid Cells/cytology/metabolism ; Spleen/pathologyPublished by: -
9A. Di Ruscio ; A. K. Ebralidze ; T. Benoukraf ; G. Amabile ; L. A. Goff ; J. Terragni ; M. E. Figueroa ; L. L. De Figueiredo Pontes ; M. Alberich-Jorda ; P. Zhang ; M. Wu ; F. D'Alo ; A. Melnick ; G. Leone ; K. K. Ebralidze ; S. Pradhan ; J. L. Rinn ; D. G. Tenen
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-10-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; CCAAT-Enhancer-Binding Proteins/*genetics ; Cell Line ; DNA/genetics/metabolism ; DNA (Cytosine-5-)-Methyltransferase/*metabolism ; DNA Methylation/*genetics ; Gene Expression Profiling ; Gene Expression Regulation/*genetics ; Genome, Human/genetics ; Humans ; RNA, Messenger/genetics/metabolism ; RNA, Untranslated/genetics/*metabolism ; RNA-Binding Proteins/metabolism ; Substrate Specificity ; Transcription, Genetic/geneticsPublished by: -
10Pronier, E., Bowman, R. L., Ahn, J., Glass, J., Kandoth, C., Merlinsky, T. R., Whitfield, J. T., Durham, B. H., Gruet, A., Hanasoge Somasundara, A. V., Rampal, R., Melnick, A., Koche, R. P., Taylor, B. S., Levine, R. L.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-09-21Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Hematopoiesis and Stem CellsPublished by: -
11Lu, X., Fernando, T. M., Lossos, C., Yusufova, N., Liu, F., Fontan, L., Durant, M., Geng, H., Melnick, J., Luo, Y., Vega, F., Moy, V., Inghirami, G., Nimer, S., Melnick, A. M., Lossos, I. S.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-11-09Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Immunobiology and Immunotherapy, Lymphoid NeoplasiaPublished by: -
12Staff View
ISSN: 1573-0948Source: Springer Online Journal Archives 1860-2000Topics: PhilosophyNotes: Conclusions It could be argued that some in the military, like certain local officials, are the last holdouts against the reform's ideological “thaw” toward religion, though Kharčev's October–November, 1989, interview inOgonëk makes clear that there are still some higher-level forces in “the apparatus” who remain opposed to some of the changes. It could be that some of the reformers themselves are concerned about the pace of change. Even in their minds the “thaw” undoubtedly has limits. They may view the present controversy over restructuring “scientific atheism” and redefining socialism's attitude toward religion as a necessary and desirable part of the dialectical process. Thus, while encouraging a tactical and more humane detente toward religion, they have not yet moved to eliminate the basis for ideological hostility toward it. They simply want that hostility to be better channeled and controlled, while exploiting the political benefits that their new-found truce with religion offers. Looking at Gorbachevism, Soviet émigré observer Aleksandr Zinov'ev believes that the reform process “in the sphere of internal political activity concerns only separate phenomena ... but by no means the very foundations of the social system, the system of power and ideology.” That system, he believes, is not yet fundamentally changing in those terms. The final answer remains to be seen.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1573-0948Source: Springer Online Journal Archives 1860-2000Topics: PhilosophyType of Medium: Electronic ResourceURL: