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Zeitlin ; R. Zimdar ; M. P. Zorzano Mier
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-07-23Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2T. J. Brodribb ; S. A. McAdam
American Association for the Advancement of Science (AAAS)
Published 2010Staff ViewPublication Date: 2010-12-18Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Abscisic Acid/metabolism/pharmacology ; Angiosperms/metabolism/*physiology ; *Biological Evolution ; Ferns/metabolism/*physiology ; Gymnosperms/metabolism/*physiology ; Light ; Lycopodiaceae/metabolism/*physiology ; Plant Epidermis/metabolism ; Plant Leaves/*metabolism ; Plant Stomata/cytology/*physiology ; Plant Transpiration ; Vapor Pressure ; Water/metabolismPublished by: -
3Bristow, T. F., Rampe, E. B., Achilles, C. N., Blake, D. F., Chipera, S. J., Craig, P., Crisp, J. A., Des Marais, D. J., Downs, R. T., Gellert, R., Grotzinger, J. P., Gupta, S., Hazen, R. M., Horgan, B., Hogancamp, J. V., Mangold, N., Mahaffy, P. R., McAdam, A. C., Ming, D. W., Morookian, J. M., Morris, R. V., Morrison, S. M., Treiman, A. H., Vaniman, D. T., Vasavada, A. R., Yen, A. S.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-06-07Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
4Eigenbrode, J. L., Summons, R. E., Steele, A., Freissinet, C., Millan, M., Navarro-Gonzalez, R., Sutter, B., McAdam, A. C., Franz, H. B., Glavin, D. P., Archer, P. D., Mahaffy, P. R., Conrad, P. G., Hurowitz, J. A., Grotzinger, J. P., Gupta, S., Ming, D. W., Sumner, D. Y., Szopa, C., Malespin, C., Buch, A., Coll, P.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-06-08Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Geochemistry, Geophysics, Planetary SciencePublished by: -
5LORD, E. ; McADAM, A. ; FELCHER, A. ; WOODS, M. ; PULASKI, B. ; HUTTER, E. ; FRELINGER, J.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
6McADAM, A. ; PULASKI, B. ; HARKINS, S. ; HUTTER, E. ; FRELINGER, J. ; LORD, E.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0022-328XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0022-328XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
9Wei, Chungwen ; Storozynsky, Eugene ; McAdam, A. J. ; Yeh, Kun-Yun ; Tilton, Brian R. ; Willis, Richard A. ; Barth, Richard K. ; Looney, R. John ; Lord, Edith M. ; Frelinger, J. G.
Springer
Published 1996Staff ViewISSN: 1432-0851Keywords: Key words Prostate-specific antigen ; Prostate adenocarcinoma ; T-cell-mediated immunity ; ImmunotherapySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Human prostate-specific antigen (PSA) has a highly restricted tissue distribution. Its expression is essentially limited to the epithelial cells of the prostate gland. Moreover, it continues to be synthesized by prostate carcinoma cells. This makes PSA an attractive candidate for use as a target antigen in the immunotherapy of prostate cancer. As a first step in characterizing the specific immune response to PSA and its potential use as a tumor-rejection antigen, we have incorporated PSA into a well-established mouse tumor model. Line 1, a mouse lung carcinoma, and P815, a mouse mastocytoma, have been transfected with the cDNA for human PSA. Immunization with a PSA-expressing tumor cell line demonstrated a memory response to PSA which protected against subsequent challenge with PSA-expressing, but not wild-type, tumors. Tumor-infiltrating lymphocytes could be isolated from PSA-expressing tumors grown in naive hosts and were specifically cytotoxic against a syngeneic cell line that expressed PSA. Immunization with tumor cells resulted in the generation of primary and memory cytotoxic T lymphocytes (CTL) specific for PSA. The isolation of PSA-specific CTL clones from immunized animals further demonstrated that PSA can serve as a target antigen for antitumor CTL. The immunogenicity studies carried out in this mouse tumor model provide a rationale for the design of methods to elicit PSA-specific cell-mediated immunity in humans.Type of Medium: Electronic ResourceURL: