Search Results - (Author, Cooperation:A. M. Meyer)
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1Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2015-04-11Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Commerce ; *Data Collection ; Female ; Humans ; *Information Dissemination ; Male ; *PrivacyPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 1432-0878Keywords: Key words: Cochlear duct ; Vestibular organ ; Tectorial membrane ; Organ of Corti ; Endolymphatic sac ; 3-Fucosyl-N-acetyl-lactosamine (CD15) ; Glycoconjugates ; Mouse (MNRI)Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract. The expression of the 3-fucosyl-N-acetyl-lac-tosamine (CD15) epitope during the embryonic development of the mouse inner ear has been immunohistochemically studied on paraffin sections from day 8.5 to day 19 of gestation. Consecutive steps of morphological development are accompanied by up- and down-regulation of CD15 expression and changing cell patterns. Expression levels are reduced once structural maturation has been accomplished. Since CD15 has been described as a determinant that is expressed during critical developmental steps, it is speculated that the changes in the epitope expression in the inner ear reflect relevant stages of differentiation. This system may thus serve as a model for understanding inner ear development.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 0022-8877Topics: PhilosophyURL: -
4Articles: DFG German National LicensesGijbels, F. ; De Meyer, A.-M. ; Bou Serhal, C. ; Van den Bossche, C. ; Declerck, J. ; Persoons, M. ; Jacobs, R.
Springer
Published 2000Staff ViewISSN: 1436-3771Keywords: Key words Dental radiography ; Digital dental radiography ; Panoramic radiography ; Diagnostic imaging ; Radiographic image enhancementSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract One of the main advantages of digital imaging is the possibility of altering display options for improved image interpretation. The aim of the present study was to evaluate the subjective image quality of direct digital panoramic images and compare the results with those obtained from conventional images. Furthermore, the effect of various filter settings on image interpretation was assessed. Panoramic images were obtained with three different types of panoramic equipment (one direct digital and two conventional units) from three groups of 54 patients with a natural dentition in all quadrants. The first series of panoramic images consisted of 54 unprocessed digital images; conventional film images (n=108) comprised the second and third series. A final series consisted of the digital images treated with three different filters (”smoothening,””sharpening,” and ”contrast enhancement”). All images were scored randomly by four experts in oral radiology on a 4-point rating scale. The results showed a statistically significant difference in scorings between the conventional and digital panoramic units. The main reason for poor image quality appeared to be a combination of blurring and overlapping in the panoramic image. The premolar region in the upper jaw was the region where most additional radiographs were needed.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1434-4726Keywords: Cochlea ; Stria vascularis ; Vestibular organ (secretory epithelium) ; Autoradiography ; Menière's diseaseSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Atrial natriuretic peptide (ANP) is a cardiac hormone known to mediate increased capillary permeability, vasodilation, and natriuresis. Since specific receptors for ANP exist in both the eye and brain, possibly playing a role in ocular and cerebrospinal fluid regulation, we postulated that ANP might also be involved in inner ear fluid dynamics. Autoradiography was used to evaluate whether and where ANP receptors are present in the inner ear. Frozen sections of the cochlea and vestibular organ from guinea pigs (n=18) were incubated in either 125J-ANP alone or together with an excess of unlabeled ANP (as control). ANP receptors were demonstrated in the stria vascularis of the cochlea and in the secretory epithelium of the ampulla and the utriculus, but not in the region of the sensory cells. These results indicate that (1) specific ANP receptors are present in the inner ear, and (2) their local distribution is congruent with those parts thought to regulate labyrinthine fluid composition and volume. We speculate that ANP contributes to the homeostasis of the inner ear fluids and may even play a role in the pathophysiology of Menière's disease.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1434-4726Keywords: Stria vascularis ; Spiral ganglion ; Organ of Corti ; Collagen ; Transgenic mouse strain animal modelSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The Mpv l7 mouse strain is a recessive transgenic mouse mutant that develops glomerulosclerosis and nephrotic syndrome at a young age. The phenotype results from a loss of function of a gene coding for a hydrophobic peroxisomal protein of 176 amino acids of 20 kDa following its destruction by retroviral integration. To investigate a potential effect of the missing Mpv 17 function on the inner ear light and electron microscopic investigations were performed on the inner ears of Mpv 17 mice and controls. These revealed degeneration of the stria vascularis and spiral ligament, loss of cochlear neurons and degeneration of the organ of Corti. The alterations observed here were similar to those described for Alport's syndrome, an inherited disorder characterized by progressive nephritis and neurosensory deafness. These findings indicate that although the molecular cause is different, the Mpv17 mouse model may share pathological mechanisms involved in patients with Alport's syndrome. At present the Mpv17 mouse appears to be a suitable animal model for this disease and may help to further elucidate the relationship between the kidney and the inner ear.Type of Medium: Electronic ResourceURL: