Search Results - (Author, Cooperation:A. M. Martin)

2018-11-29

American Physical Society (APS)

1098-0121

1095-3795

Physics

Structure, structural phase transitions, mechanical properties, defects

2013-05-04

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Computer Science

Medicine

Natural Sciences in General

Physics

Animals ; Antelopes/*physiology ; Female ; Male ; *Mating Preference, Animal ; *Predatory Behavior ; *Sexual Behavior, Animal

2018-02-02

American Physical Society (APS)

1098-0121

1095-3795

Physics

Superfluidity and superconductivity

2018-03-13

American Physical Society (APS)

1098-0121

1095-3795

Physics

Electronic structure and strongly correlated systems

2016-04-28

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

AIDS Vaccines/administration & dosage/immunology ; Animals ; Antibodies, Monoclonal/administration & dosage/blood/genetics/immunology ; Antibodies, Neutralizing/administration & dosage/blood/genetics/immunology ; Female ; HIV Antibodies/*administration & dosage/blood/genetics/*immunology ; HIV Infections/immunology/prevention & control/transmission ; Half-Life ; Immunoglobulin Fc Fragments/chemistry/genetics/immunology ; Macaca mulatta/immunology/virology ; Male ; Mutation/genetics ; Protein Structure, Tertiary ; SAIDS Vaccines/administration & dosage/immunology ; Simian Acquired Immunodeficiency Syndrome/blood/*immunology/*prevention & control ; Simian Immunodeficiency Virus/*immunology ; Time Factors

2013-05-11

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Computer Science

Medicine

Natural Sciences in General

Physics

Animals ; Antibodies, Neutralizing/blood/*immunology ; Epitope Mapping ; HIV Antibodies/blood/*immunology ; HIV Infections/blood/*immunology ; HIV-1/*immunology/isolation & purification ; Humans ; Immunodominant Epitopes/chemistry/immunology ; Macaca ; Neutralization Tests ; Protein Conformation ; Serum/immunology

2014-06-14

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Computer Science

Medicine

Natural Sciences in General

Physics

2013-11-01

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Animals ; Antibodies, Neutralizing/*therapeutic use ; Antigens, CD4/metabolism ; Binding Sites/immunology ; HIV Antibodies/*therapeutic use ; HIV Envelope Protein gp120/immunology ; HIV-1/*immunology ; *Immunotherapy ; Macaca/immunology ; Molecular Sequence Data ; Peptide Fragments/immunology ; Simian Acquired Immunodeficiency Syndrome/prevention & control/*therapy ; Simian Immunodeficiency Virus/*physiology ; Time Factors ; Viral Load ; Viremia/*therapy

2012-12-14

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Antarctic Regions ; Computer Simulation ; Global Warming ; *Ice Cover ; *Models, Theoretical ; *Snow

2018-04-19

Royal Society

2054-5703

Natural Sciences in General

behaviour, physiology, health and disease and epidemiology

2018-05-05

American Association for the Advancement of Science (AAAS)

2375-2548

Natural Sciences in General

1089-7623

AIP Digital Archive

Physics

Electrical Engineering, Measurement and Control Technology

An apparatus consisting basically of a fast entry load-lock system with sample manipulation and heating capacity is described. Special attention is paid to the differential pumping details and the sample heating. This low-cost system is within the possibilities of tradesmen and workshops. © 1995 American Institute of Physics.

Electronic Resource

1399-3038

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Ataxia telangiectasia (AT) is an infrequent condition, which is difficult to diagnose in children. The objective was to describe the evolution of all affected patients controlled in our hospital and to highlight the keys for an early diagnosis considering the variability of immunological disorders. The present study is a retrospective review of all patients diagnosed and controlled of AT in our hospital. Twelve patients were found, including two couples of siblings. The most frequent reason for consultation was unstable gait. Seven patients suffered repeated infections, being pneumonia the most frequent cause of infection, followed by sinusitis. One of the patients developed Burkitt's lymphoma, and another patient, Hodgkin's lymphoma, which caused the death of the patient at the age of 11. A couple of siblings aged 17 and 22 years developed insulin-resistant diabetes mellitus. The most frequent immunity disorders were the IgG deficiency and the decrease of T lymphocytes. Seven patients were treated with non-specific gamma-globulin. By the end of the follow-up, 8 patients (ages ranged 7 to 12 years) lost gait. Molecular genetic testing was conducted in patients who are still cared for in our hospital. Clinical suspicion of this entity will lead to an early diagnosis, the treatment of complications, and to provide genetic counselling for the families.

Electronic Resource

1750-3841

Blackwell Publishing Journal Backfiles 1879-2005

Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition

Process Engineering, Biotechnology, Nutrition Technology

An acid-tolerant fungus, Scytalidium acidophilum, was cultivated in peat extract for potential use as a single-cell protein (SCP) source. In shake flask fermentations with a 0.3% yeast extract diluted peat extract medium, it was found that the best conditions for growth occurred at pH 2.0 and 25°C. The maximum biomass concentration was produced after 10 days, with no significant differences for agitation rates between 100 and 200 rpm. Microbial contamination was not observed in nonaseptic operations. The protein content and amino acid composition of the mycelium produced compares with those reported for S. acidophilum grown in other fermentation media. The advantages of growing S. acidophilum in acid peat extract are presented.

Electronic Resource

1748-7692

Blackwell Publishing Journal Backfiles 1879-2005

Biology

The apparent lack of significant recovery of western North Atlantic right whale populations may be related to the availability of prey in exploitable densities. We have attempted to estimate the concentration of zooplankton required by right whales to obtain a net energetic benefit over the long term, using estimated values for body weight, metabolic rate, assimilation efficiency, time spent feeding, mouth size and swimming speed. The estimated range of required energy densities is 7.57 to 2,394 kcal m−3 (3.17 × 104 to 1.00 × 107 joule m−3). These values are from one to more than three orders of magnitude greater than the densest concentration sampled in the vicinity of right whale aggregations in the Great South Channel. Right whales must seek out and exploit extremely dense patches of prey organisms in order to feed efficiently. The presence of such dense patches of zooplankton is likely to be a primary characteristic of spring, summer and fall right whale habitats.

Electronic Resource

1745-4549

Blackwell Publishing Journal Backfiles 1879-2005

Process Engineering, Biotechnology, Nutrition Technology

The optimum pH, time and acid solution-fruit ratio for the extraction and purification of pectin was determined utilizing grapefruit rinds as a pectin source. The determination of pectin content utilizing the ethanol yield method and the calcium pectate method was conducted in 13 and 7 tropical fruits, respectively. The variation in pectin content from the green to the mature and to the ripe stages was determined in 6 fruits. Finally, estimation of the percentage of methoxylation, as an indication of the gel forming potential of the pectin, was measured in 3 of the most promising pectin source fruits.

Electronic Resource

1420-9071

Springer Online Journal Archives 1860-2000

Biology

Medicine

Zusammenfassung Pathologische Veränderungen bei Kaninchen, Hunden und Affen nach intrazysternaler Verabreichung von Bakterienendotoxinen sind einander sehr ähnlich, während sie nach i.v. Injektion bei allen 3 Tiergruppen auffallend verschieden sind. Dies führt zur Annahme, dass die Wirkung des Endotoxins zur Hauptsache offenbar nicht über das Zentralnervensystem geht.

Electronic Resource

1432-1211

Key words KIR ; Multigene family ; Gene duplication ; Evolution

Springer Online Journal Archives 1860-2000

Biology

Medicine

Abstract. Natural killer (NK) immunoglobulin-like receptors (KIRs) are a family of polymorphic receptors which interact with specific motifs on HLA class I molecules and modulate NK cytolytic activity. In this study, we analyzed a recently sequenced subgenomic region on chromosome 19q13.4 containing eight members of the KIR receptor repertoire. Six members are clustered within a 100-kb continuous sequence. These genes include a previously unpublished member of the KIR gene family 2DS6, as well as 2DL1, 2DL4, 3DL1, 2DS4, 3DL2, from centromere to telomere. Two additional KIR genes, KIRCI and 2DL3, which may be located centromeric of this cluster were also analyzed. We show that the KIR genes have undergone repeated gene duplications. Diversification between the genes has occurred postduplication primarily as a result of retroelement indels and gene truncation. Using pre- and postduplication Alu sequences identified within these genes as evolutionary molecular clocks, the evolution and duplication of this gene cluster is estimated to have occurred 30–45 million years ago, during primate evolution. A proposed model of the duplication history of the KIR gene family leading to their present organization is presented.

Electronic Resource

1432-072X

Penicillium simplicissimum ; Species description ; Phenolic compounds ; Phloroglucinol ; Aerobic degradation

Springer Online Journal Archives 1860-2000

Biology

Abstract The pathway for the aerobic catabolism of 1,3,5-trihydroxybenzene (phloroglucinol) by a new strain of Penicillium was investigated using both in vivo and in vitro cell-free systems. The fungal strain was isolated by enrichment on phloroglucinol and identified as P. simplicissimum (Oud) Thom. It grew optimally at pH 5.5 and 27°C with 119 mM (1.5%w/v) of phloroglucinol in a basal mineral salts medium. Vapours of the crystalline substrate placed in a Petri-plate lid supported the growth of the fungal colonies on the agar surface. Mycelia grown on phloroglucinol accumulated 1,2,4-trihydroxybenzene and resorcinol in the medium. Washed, resting mycelia grown on phloroglucinol, when resuspended in a buffer utilized oxygen in the presence of catechol, resorcinol, pyrogallol and phloroglucinol. A NADPH-dependent reductase in the cell-free extract reduced phloroglucinol to dihydrophloroglucinol. This electron donor could not be replaced by NADH. Resorcinol hydroxylase, phloroglucinol reductase, catechol-1,2-oxygenase, and catechol-2,3-oxygenase were detected in cell-free extracts of mycelia grown on phloroglucinol. The possible steps in the degradation of phloroglucinol are discussed.

Electronic Resource

1573-7284

Clinical manifestations ; Diagnosis ; Epidemiology ; HIV-1 ; HTLV-I ; HTLV-II

Springer Online Journal Archives 1860-2000

Medicine

Abstract The human T-lymphotropic virus type II (HTLV-II) has recently been associated with the genesis of some subacute neurological syndromes and, rarely, with atypical T-lymphoid malignancies. The virus is endemic in some Amerindian and African tribes, and among intravenous drug users (IDUs) in North America and Europe. Given that HTLV-II is transmitted by the same routes as other human retroviruses, the screening of antibodies to HTLV-II in blood donors has became a matter of controversy in some countries. Herein, we describe the clinical, epidemiological and virological features of 113 individuals with HTLV-II infection identified in Spain up to September 1995. Most of them (94/113; 83%) were male, and all but seven were natives. Four were African immigrants living in Madrid and 3 had been born in other European countries. All but six subjects were IDUs, and sexual transmission of HTLV-II and transfusion were involved in five and one individual, respectively. Eighty-four percent of the IDUs infected with HTLV-II were co-infected by HIV-1 (93/107). Clinical manifestations potentially linked to HTLV-II were absent, although an IDU male co-infected by HIV-1 and HTLV-II developed a severe non-inflammatory proximal myopathy. In conclusion, HTLV-II infection is present in Spain, mainly among IDUs, with a growing incidence and a current overall prevalence of 2.0 percent.

Electronic Resource