ILSE | Search Results - (Author, Cooperation:A. Lombardo)

1

T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency

Brigida, I., Zoccolillo, M., Cicalese, M. P., Pfajfer, L., Barzaghi, F., Scala, S., Oleaga-Quintas, C., Alvarez-Alvarez, J. A., Sereni, L., Giannelli, S., Sartirana, C., Dionisio, F., Pavesi, L., Benavides-Nieto, M., Basso-Ricci, L., Capasso, P., Mazzi, B., Rosain, J., Marcus, N., Lee, Y. N., Somech, R., Degano, M., Raiola, G., Caorsi, R., Picco, P., Moncada Velez, M., Khourieh, J., Arias, A. A., Bousfiha, A., Issekutz, T., Issekutz, A., Boisson, B., Dobbs, K., Villa, A., Lombardo, A., Neven, B., Moshous, D., Casanova, J.-L., Franco, J. L., Notarangelo, L. D., Scielzo, C., Volpi, S., Dupre, L., Bustamante, J., Gattorno, M., Aiuti, A.
American Society of Hematology (ASH)
Published 2018

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Publication Date:	2018-11-30
Publisher:	American Society of Hematology (ASH)
Print ISSN:	0006-4971
Electronic ISSN:	1528-0020
Topics:	Biology Medicine
Keywords:	Immunobiology and Immunotherapy
Published by:	http://www.hematology.org/

Latest Papers from Table of Contents or Articles in Press

2

Expression of PD-L1, indoleamine 2,3-dioxygenase and the immune microenvironment in gastric adenocarcinoma

Pallavi A. Patil, Andrew M. Blakely, Kara A. Lombardo, Jason T. Machan, Thomas J. Miner, Li-Juan Wang, Alexander S. Marwaha, Andres Matoso
Wiley-Blackwell
Published 2018

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Publication Date:	2018-03-06
Publisher:	Wiley-Blackwell
Print ISSN:	0309-0167
Electronic ISSN:	1365-2559
Topics:	Medicine
Published by:	http://www.wiley.com/wiley-blackwell

Latest Papers from Table of Contents or Articles in Press

3

Targeted genome editing in human repopulating haematopoietic stem cells

P. Genovese ; G. Schiroli ; G. Escobar ; T. Di Tomaso ; C. Firrito ; A. Calabria ; D. Moi ; R. Mazzieri ; C. Bonini ; M. C. Holmes ; P. D. Gregory ; M. van der Burg ; B. Gentner ; E. Montini ; A. Lombardo ; L. Naldini
Nature Publishing Group (NPG)
Published 2014

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Publication Date:	2014-05-30
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Animals ; Antigens, CD34/metabolism ; DNA, Complementary/genetics ; Endonucleases/metabolism ; Fetal Blood/cytology/metabolism/transplantation ; Gene Targeting/methods ; Genome, Human/genetics ; Hematopoiesis/genetics ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/cytology/metabolism ; Humans ; Interleukin Receptor Common gamma Subunit/genetics ; Male ; Mice ; Mutation/genetics ; Targeted Gene Repair/methods ; X-Linked Combined Immunodeficiency Diseases/genetics/therapy
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

4

MEMBRANE-BOUND NEURAMINIDASE IN THE BRAIN OF DIFFERENT ANIMALS: BEHAVIOUR OF THE ENZYME ON ENDOGENOUS SIALO DERIVATIVES AND RATIONALE FOR ITS ASSAY

Tettamanti, G. ; Preti, A. ; Lombardo, A. ; Suman, T. ; Zambotti, V.

Oxford, UK : Blackwell Publishing Ltd
Published 1975

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ISSN:	1471-4159
Source:	Blackwell Publishing Journal Backfiles 1879-2005
Topics:	Medicine
Notes:	—The activity of brain membrane-bound neuraminidase on endogenous and exogenous substrates was comparatively studied in various animals (rat, chicken, rabbit, pig, calf and human). The maximum rate of hydrolysis of endogenous substrates by membrane-bound neuraminidase (using a crude preparation of the enzyme) was different in the various animals (from 0·05 to 0·73 units, referred to 1 mg protein) and was obtained under similar but not identical optimum conditions (pH from 4·1 to 5·1; requirement or not of Triton X-100). The maximum degree of hydrolysis of endogenous substates was also different (from 15 to 27 nmol released NeuNAc/mg protein) and was obtained within different incubation periods (from 2 to 18 h). It corresponded (in rabbit, calf, human brain only), or not, to the actual exhaustion of the endogenous substrates.The endogenous substrates were recognized as both gangliosides and sialoglycoproteins. The extent of hydrolysis of sialoglycoproteins varied from 1·5% in rabbit to 15·6% in chicken brain; the hydrolysis of gangliosides (ranging from 14·1% in pig to 53·7% in rabbit brain) reached only in some animals (rabbit, calf, human) the complete transformation of major oligosialogangliosides into the neuraminidase resistant monosialoganglioside GMI. Upon addition of exogenous substrates (sialyl-lactose, ganglioside GD1a, brain sialopeptides, ovine submaxillary mucin) the actual rate of liberation of total NeuNAc (from both endogenous and exogenous substrates) considerably exceeded, although at a different extent (depending on the animal and on the added substrate used) the rate of hydrolysis of sole endogenous substrates. The possibility of an accurate assay of brain membrane-bound neuraminidase in a crude enzyme preparation is evaluated and guidelines for the assay procedure suggested.
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1111/j.1471-4159.1975.tb04349.x

Articles: DFG German National Licenses

5

Removal of N-acetylneuraminic acid from particulate sialoglycoproteins by endogenous membrane bound neuraminidase in calf brain

PretI, A. ; LombardO, A. ; TettamantI, G. ; ZambottI, V.

Oxford, UK : Blackwell Publishing Ltd
Published 1973

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ISSN:	1471-4159
Source:	Blackwell Publishing Journal Backfiles 1879-2005
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1111/j.1471-4159.1973.tb06040.x

Articles: DFG German National Licenses

6

Behaviour of some lysosomal enzymes in the plasma of insulin dependent diabetic patients during artificial pancreas treatment

Burlina, A.B. ; Goi, G. ; Fabi, A. ; Lombardo, A. ; Gaburro, D. ; Tettamanti, G.

Amsterdam : Elsevier

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ISSN:	0009-9120
Keywords:	artificial pancreas ; diabetes ; lysosomal enzymes ; plasma clinical enzymology
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0009-9120(87)90009-9

Articles: DFG German National Licenses

7

Parallelism of subcellular location of major particulate neuraminidase and gangliosides in rabbit brain cortex

Tettamanti, G. ; Preti, A. ; Lombardo, A. ; Bonali, F. ; Zambotti, V.

Amsterdam : Elsevier

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ISSN:	0005-2760
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Chemistry and Pharmacology Medicine Physics
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0005-2760(73)90185-9

Articles: DFG German National Licenses

8

Molecular organization (topography) of cytochrome P-450"1"1"β in mitochondrial membrane and phospholipid vesicles as studied by trypsinolysis

Lombardo, A. ; Laine, M. ; Defaye, G. ; Monnier, N. ; Guidicelli, C. ; Chambaz, E.M.

Amsterdam : Elsevier

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ISSN:	0005-2736
Keywords:	Cytochrome P-450"1"1"β ; Membrane topography ; Steroid hydroxylation ; Trypsin treatment
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology Chemistry and Pharmacology Medicine Physics
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0005-2736(86)90388-3

Articles: DFG German National Licenses

9

Studies on brain cytosol neuraminidase. II. Extractability, solubility and intraneuronal distribution of the enzyme in pig brain

Venerando, B. ; Preti, A. ; Lombardo, A. ; Cestaro, B. ; Tettamanti, G.

Amsterdam : Elsevier

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ISSN:	0005-2744
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0005-2744(78)90252-8

Articles: DFG German National Licenses

10

Studies on brain membrane-bound neuraminidase - I. General properties of the enzyme prepared from calf brain

Preti, A. ; Lombardo, A. ; Cestaro, B. ; Zambotti, S. ; Tettamanti, G.

Amsterdam : Elsevier

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ISSN:	0005-2744
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0005-2744(74)90515-4

Articles: DFG German National Licenses

11

Assay of brain particulate neuraminidase III. Preparation of the enzyme devoid of endogenous substrates

Tettamanti, G. ; Preti, A. ; Lombardo, A. ; Gasparini, M. ; Zambotti, V.

Amsterdam : Elsevier

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ISSN:	0005-2744
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0005-2744(72)90981-3

Articles: DFG German National Licenses

12

Studies of brain membrane-bound neuraminidase - II. Effect of detergents on the kinetics of the enzyme prepared from calf brain

Tettamanti, G. ; Cestaro, B. ; Lombardo, A. ; Preti, A. ; Venerando, B. ; Zambotti, V.

Amsterdam : Elsevier

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ISSN:	0005-2744
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0005-2744(74)90516-6

Articles: DFG German National Licenses

13

The esters of p-hydroxy-benzoate (parabens) inhibit the release of lysosomal enzymes by mitogen-stimulated peripheral human lymphocytes in culture

Bairati, C. ; Goi, G. ; Lombardo, A. ; Tettamanti, G.

Amsterdam : Elsevier

Staff View

ISSN:	0009-8981
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0009-8981(94)90181-3

Articles: DFG German National Licenses

14

Influence of age and sex on five human plasma lysosomal enzymes assayed by automated procedures

Lombardo, A. ; Goi, G.C. ; Marchesini, S. ; Caimi, L. ; Moro, M. ; Tettamanti, G.

Amsterdam : Elsevier

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ISSN:	0009-8981
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0009-8981(81)90148-0

Articles: DFG German National Licenses

15

Optimal conditions for the assay of fibroblast neuraminidase with different natural substrates

Caimi, L. ; Lombardo, A. ; Preti, A. ; Wiesmann, U. ; Tettamanti, G.

Amsterdam : Elsevier

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ISSN:	0005-2744
Keywords:	Assay conditions ; Fibroblast ; Natural substrate ; Neuraminidase
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Biology
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0005-2744(79)90234-1

Articles: DFG German National Licenses

16

Enzymes of lysosomal origin in human plasma and serum: Assay conditions and parameters influencing the assay

Lombardo, A. ; Caimi, L. ; Marchesini, S. ; Goi, G.C. ; Tettamanti, G.

Amsterdam : Elsevier

Staff View

ISSN:	0009-8981
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0009-8981(80)90339-3

Articles: DFG German National Licenses

17

Circadian and circannual rhythms of several enzymes of lysosomal origin in human plasma

Goi, G. ; Fabi, A. ; Lombardo, A. ; Burlina, A.B. ; Tettamanti, G. ; Montalbetti, N. ; Cavalleri, M. ; Halberg, F.

Amsterdam : Elsevier

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ISSN:	0009-8981
Keywords:	Circadian rhythm ; Circannual rhythm ; Human plasma ; Lysosomal enzyme
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0009-8981(88)90168-4

Articles: DFG German National Licenses

18

Enzymes of lysosomal origin in plasma of twin neonates

Goi, G. ; Burlina, A.B. ; Bairati, C. ; Bordugo, A. ; Zanardo, V. ; Zacchello, F. ; Tettamanti, G. ; Lombardo, A.

Amsterdam : Elsevier

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ISSN:	0009-8981
Keywords:	Lysosomal enzymes ; Neonates ; Plasma ; Twins
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://dx.doi.org/10.1016/0009-8981(93)90303-L

Articles: DFG German National Licenses

19

Behaviour of several enzymes of lysosomal origin in human plasma during whole blood storage

Lombardo, A. ; Goi, G. ; Guagnellini, E. ; Fabi, A. ; Sciorelli, G. ; Burlina, A.B. ; Tettamanti, G.

Amsterdam : Elsevier

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ISSN:	0009-8981
Keywords:	Blood plasma ; Fluorimetric enzyme assay procedures ; Lysosomal enzymes ; Whole blood storage
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0009-8981(84)90088-3

Articles: DFG German National Licenses

20

The lysosomal N-acetyl-β-d-glucosaminidase (NAG) isoenzymes in plasma: Study of distribution in a general population by a simple routine chromatofocusing procedure

Goi, G. ; Bairati, C. ; Roggi, C. ; Maccarini, L. ; Tettamanti, G. ; Meloni, C. ; Lombardo, A.

Amsterdam : Elsevier

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ISSN:	0009-8981
Keywords:	Distribution in a general population ; Isoenzymes ; N-Acetyl-β-d-glucosaminidase ; Plasma levels ; Routine chromatofocusing procedure
Source:	Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:	Medicine
Type of Medium:	Electronic Resource
URL:	http://linkinghub.elsevier.com/retrieve/pii/0009-8981(93)90021-U

Articles: DFG German National Licenses

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