Search Results - (Author, Cooperation:A. Lamb)

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  1. 1
    Aggarwal, M., Leser, G. P., Kors, C. A., Lamb, R. A.
    The American Society for Microbiology (ASM)
    Published 2018
    Staff View
    Publication Date:
    2018-02-14
    Publisher:
    The American Society for Microbiology (ASM)
    Print ISSN:
    0022-538X
    Electronic ISSN:
    1098-5514
    Topics:
    Medicine
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Richard A. Lamb, Nigel T. Lucas, Guillaume Lessene, Bill C. Hawkins
    American Chemical Society (ACS)
    Published 2018
    Staff View
    Publication Date:
    2018-07-27
    Publisher:
    American Chemical Society (ACS)
    Print ISSN:
    0022-3263
    Electronic ISSN:
    1520-6904
    Topics:
    Chemistry and Pharmacology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    B. Phalan ; R. E. Green ; L. V. Dicks ; G. Dotta ; C. Feniuk ; A. Lamb ; B. B. Strassburg ; D. R. Williams ; E. K. zu Ermgassen ; A. Balmford
    American Association for the Advancement of Science (AAAS)
    Published 2016
    Staff View
    Publication Date:
    2016-01-30
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Agriculture ; Animals ; Cattle ; Ecosystem ; *Environmental Restoration and Remediation ; Equidae ; Felidae ; Livestock ; Sheep
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-07-13
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Geochemistry, Geophysics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2018-05-10
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Electronic ISSN:
    2375-2548
    Topics:
    Natural Sciences in General
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Lamey, P.-J. ; Lamb, A. B. ; Forsyth, A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1987
    Staff View
    ISSN:
    1600-0536
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Elmore, M. J. ; Lamb, A. J. ; Ritchie, G. Y. ; Douglas, R. M. ; Munro, A. ; Gajewska, A. ; Booth, I. R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1990
    Staff View
    ISSN:
    1365-2958
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    The mechanism by which N-ethylmaleimide (NEM) elicits potassium efflux from Escherichia coli has been investigated. The critical factor is the formation of specific glutathione metabolites that activate transport systems encoded by the kefB and kefC gene products. Formation of N-ethyl-succinimido-S-glutathione (ESG) leads to the activation of potassium efflux via these transport systems. The addition of dithiothreitol and other reducing agents to cells reverses this process by causing the breakdown of ESG and thus removing the activator of the systems. Chlorodinitrobenzene, p-chloromercuribenzoate and phenylmaleimide provoke similar effects to NEM. Iodoacetate, which leads to the formation of S-carboxymethyl-glutathione, does not activate the systems but does prevent the action of NEM. It is concluded that the KefB and KefC systems are gated by glutathione metabolites and that the degree to which they are activated is dependent upon the nature of the substituent on the sulphydryl group.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Munro, A. W. ; Ritchie, G. Y. ; Lamb, A. J. ; Douglas, R. M. ; Booth, I. R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1991
    Staff View
    ISSN:
    1365-2958
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    The kefC gene of Escherichia coli encodes a potassium-efflux system that is regulated by glutathione metabolites. The close proximity of the E. coli kefC gene to the folA gene, encoding dihydrofolate reductase, has been utilized to clone the structural gene for the system from a Clarke-Carbon plasmid. The cloned gene has been refined to a region of DNA approximately 2.1 kb in length using exonuclease III-generated deletions and random Muc/M1734 (IacZ) insertions. The direction of transcription has been deduced from the orientation of the Mu insertions in the cloned DNA. A hybrid protein consisting of approximately two thirds of the KefC protein fused to β-galactosidase has been shown to be membrane-located. The DNA sequence of the gene has been determined and an open reading frame of 1.86kb has been located which could encode a protein of 620 amino acids (7901 0Da). Using the T7 expression system a membrane protein, of apparent molecular mass 55–60 kDa, has been shown to be encoded by the kefC gene. The predicted protein sequence shows a highly hydrophobic amino-terminus and a strongly hydrophilic carboxy-terminus, Comparison of the amino acid sequence of the kefC gene product with those of two glutathione-utilizing enzymes, glyoxalase and dehalogenase, has revealed some similarities.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Lamey, P.-J. ; Lamb, A. B. ; Hughes, A. ; Milligan, K. A. ; Forsyth, A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1994
    Staff View
    ISSN:
    1600-0714
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    A subgroup of patients with burning mouth syndrome was investigated. The clinical history of these patients differed from the norm in that symptoms were intermittent and affected unusual sites. In addition, routine investigations were supplemented with a more detailed psychological evaluation than reported previously and also a possible allergic component was studied by patch testing. The study has shown that this subgroup differs from burning mouth syndrome patients overall in that emotional instability and allergic reactions, particularly to food additives, are of etiological significance and require to be taken into consideration in terms of patient management.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Paterson, A. J. ; Lamb, A. B. ; Clifford, T. J. ; Lamey, P.-J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1600-0714
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    This study investigated 84 patients with burning mouth syndrome (BMS), who were asked to complete a hospital anxiety and depression (HAD) scale questionnaire. A control group of 69 patients was also included. All patients were interviewed regarding parafunctional habits and were subjectively examined for signs of occlusal wear of the natural teeth or dentures. The results demonstrated that parafunctional habits were present in 61% of patients with BMS. There was a statistically significantly relationship between parafunctional habits and anxiety as indicated by the HAD scale, but not with depression.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Samaranayake, L. P. ; Lamb, A. B. ; Lamey, P.-J. ; MacFarlane, T. W.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1600-0714
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The oral carriage of Candida species and coliforms in a healthy adult population and a group of patients with burning mouth syndrome (BMS) was investigated. The intra-oral prevalence of Candida species and coliforms was higher in the BMS group compared with the controls. The most frequent yeast isolated from the BMS group was Candida albicans while Enterobacter and Klebsiella species were the most prevalent coliforms. The possible reasons and the significance of the above findings are discussed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Shick, J. M. ; Taylor, W. F. ; Lamb, A. N.
    Springer
    Published 1981
    Staff View
    ISSN:
    1432-1793
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract The gonad index in the deposit-feeding asteroid Ctenodiscus crispatus (Retzius) in the Gulf of Maine (USA) is seasonally less variable than in any other sea star, ranging from 2.99 to 4.98% of dry body weight in females and from 2.28 to 3.42% in males, and varies in concert with, rather than reciprocal to, the pyloric caecum index. Biochemical composition and, hence, caloric content, of the gonads also show little seasonal change, suggesting that reproduction is aseasonal and continuous in this population. Oocyte development is asynchronous, all females having a full size range of oocytes (from less than 30 μm to greater than 400 μm diameter) throughout the year. Seasonally determined size-frequency distributions of juveniles, oocyte cytology and size-frequency distributions, responsiveness of adult females to 1-methyladenine, and oxygen uptake rates indicate that variations in reproductive intensity are superimposed on continuous reproduction, and seem related to changes in phytoplankton production rather than to temperature. The rich neutral lipid content (ca. 50% of total lipid) and large egg size (〉400 μm) in the ovaries suggest that development is direct. The population is extremely variable genetically, polymorphism among 13 enzyme-coding genes being 77% and average heterozygosity being 0.174. The reproductive pattern and genetic variation in the eurybathic C. crispatus are similar to those in deep-sea echinoderms. This may be related to the constancy of the population's detrital food source, to small-scale heterogeneity of its physical environment, and to low individual vagility.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Dunlop, E. ; Lamb, A. ; King, D.
    Springer
    Published 1976
    Staff View
    ISSN:
    1439-0973
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Description / Table of Contents:
    Zusammenfassung Die asymptomatische Gonorrhöe ist das Hauptproblem bei der Kontrolle dieser Krankheit. Nur 12 Prozent der erfaßten infizierten Frauen im Jahre 1974 kamen wegen Beschwerden zur Untersuchung im Gegensatz zu 97 Prozent der infizierten heterosexuellen Männer und nur 35 Prozent der homosexuellen Männer mit isolierter gonorrhoischer Proktitis. Im Vergleich mit heterosexuellen Männern hatten homosexuelle Männer zweimal so viel sexuelle Kontakte nach der Infektion und eine höhere Inzidenz einer Syphilis im Frühstadium. 84 Prozent hatten passiven anorektalen Verkehr gehabt. 97 Prozent der Männer mit gonorrhoischer Urethritis meldeten sich wegen Beschwerden, aber gelegentlich (insbesondere nach unzureichender Behandlung) kann die gonorrhoische Urethritis bei Männern klinisch stumm sein und sie kann sogar Untersuchungen der nächtlichen urethralen Sekretion zur Diagnose erfordern. Für Frauen und für homosexuelle Männer, die passiven anorektalen (oder oralen) Verkehr gehabt haben, sollte der Grund ihres Kommens nicht das Vorhandensein von Symptomen sein, sondern ein mögliches eingegangenes Infektionsrisiko. Routine-Untersuchungen der Analgegend auf Gonorrhöe sind bei Frauen nach entsprechendem Geschlechtsverkehr unbedingt erforderlich, gleichfalls bei den meisten homosexuellen Männern, weil über 80 Prozent dieser Männer wohl einen passiven anorektalen Verkehr gehabt haben werden. Da Gonokokken-Infektionen nach Behandlungsversagen bei Männern und Frauen oft asymptomatisch sind, ist das Verschwinden der Symptome keine verläßliche Indikation für eine erfolgreiche Behandlung. Ständige Überwachung in Form von Abstrichen und kulturellen Untersuchungen ist auf alle Fälle erforderlich.
    Notes:
    Summary Clinically silent gonorrhoea is the major problem in the control of the disease. Only 12 per cent of infected women reported in 1974 because of symptoms, compared with 97 per cent of infected heterosexual men and only 35 per cent of homosexual men with gonococcal proctitis alone. Homosexual men, compared with heterosexual men, had twice as many subsequent sexual contacts after infection and had a higher incidence of early syphilis. Eighty-four per cent had experienced passive anorectal intercourse. Ninety-seven per cent of men with gonococcal urethritis reported because of symptoms, but occasionally (particularly after unsuccessful treatment) urethral gonorrhoea in men may be clinically silent and even require tests of the overnight urethral secretion for diagnosis. For women, and for homosexual men who have had passive anorectal (or oral) intercourse, the indication for attendance for tests for gonorrhoea should be having run the risk, and not the presence of symptoms. Routine tests of the anorectum for gonorrhoea are essential in cases of women at risk, and for most homosexual men since over 80 per cent of these men will have had passive anorectal intercourse. Because gonococcal infections following treatment-failure are often clinically silent in both women and men, symptoms cannot be relied upon to indicate such failure. Follow-up smears and cultures are always essential.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
  15. 15
    Staff View
    ISSN:
    1618-2650
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    1618-2650
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses