Search Results - (Author, Cooperation:A. G. Clark)

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  1. 1
    A. Keinan ; A. G. Clark
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-05-15
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Asian Continental Ancestry Group/genetics ; European Continental Ancestry Group/genetics ; Gene Frequency ; Genetic Association Studies ; Genetic Predisposition to Disease ; *Genetic Variation ; Genetics, Population/methods ; Genome, Human ; Haplotypes ; Heterozygote ; Humans ; Models, Genetic ; Mutation ; Polymorphism, Single Nucleotide ; *Population Density ; *Population Growth ; Sample Size ; Sequence Analysis, DNA
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    A. G. Clark ; P. W. Messer
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-01-03
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Anopheles/*classification/*genetics ; *Evolution, Molecular ; *Genome, Insect ; Humans ; Insect Vectors/*genetics ; Malaria/*transmission
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    J. K. Goodrich ; E. R. Davenport ; J. L. Waters ; A. G. Clark ; R. E. Ley
    American Association for the Advancement of Science (AAAS)
    Published 2016
    Staff View
    Publication Date:
    2016-04-30
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bacteria/*classification/genetics ; Diet ; *Genome-Wide Association Study ; Genotype ; Humans ; Mice ; Microbiota/genetics/*physiology ; Phenotype ; *Quantitative Trait Loci ; Species Specificity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    A. G. Clark
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-04-25
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; *Evolution, Molecular ; Female ; Gene Dosage/*genetics ; Humans ; Male ; Mammals/*genetics ; Y Chromosome/*genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    M. Lang ; S. Murat ; A. G. Clark ; G. Gouppil ; C. Blais ; L. M. Matzkin ; E. Guittard ; T. Yoshiyama-Yanagawa ; H. Kataoka ; R. Niwa ; R. Lafont ; C. Dauphin-Villemant ; V. Orgogozo
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-09-29
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Animals ; Cactaceae/*metabolism ; Cholesterol/metabolism ; Conserved Sequence ; Dehydrocholesterols/metabolism ; Drosophila/genetics/*physiology ; Drosophila Proteins/chemistry/*genetics/metabolism ; *Food Chain ; Molecular Sequence Data ; *Mutation ; Oxygenases/chemistry/*genetics/metabolism ; Protein Conformation ; RNA Interference ; Selection, Genetic ; Species Specificity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    R. B. Corbett-Detig ; J. Zhou ; A. G. Clark ; D. L. Hartl ; J. F. Ayroles
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-11-08
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; Animals ; Arabidopsis/genetics ; Drosophila melanogaster/*genetics ; Epistasis, Genetic/*genetics ; Genetic Speciation ; Genome/*genetics ; Genotype ; Mutation ; Zea mays/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    REYNOLDS, J. R. ; WALT, R. P. ; CLARK, A. G. ; HARDCASTLE, J. D. ; LANGMAN, M. J. S.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1987
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Intragastric pH was measured continuously from 1800 to 1200 hours the following day in 22 duodenal ulcer patients and in eight gastric ulcer patients, all of whom had been admitted as emergencies with acute upper gastrointestinal haemorrhage. The effects of intravenous cimetidine or ranitidine were compared with no treatment. In patients with duodenal ulcer, median intragastric pH was 1.8 (range 1.0–4.9) in the group receiving no treatment. In the cimetidine group (400 mg, 6-hourly, n= 8) median pH was 4.7 (range 1.5–7.7) and after ranitidine (50 mg, 6-hourly, n= 10) it was 3.8 (range 1.2–7.8). The pH remained above 4.0 for 67% of the recording time with cimetidine, 47% with ranitidine and for only 3% with placebo. Intragastric pH in gastric ulcer patients without treatment was higher (median 3.4, range 1.0–6.9) than in duodenal ulcer patients with treatment. Both H2 antagonists raised intragastric pH in patients with gastric ulcer and maintained a gastric pH of 〉 4.0 for at least 50% of the time. Presently recommended i.v. doses of cimetidine and ranitidine do not consistently maintain gastric pH above 4.0 for long periods in patients with peptic ulcer bleeding.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    CLARK, A. G. ; MANSFORD, K. R. L.

    [s.l.] : Nature Publishing Group
    Published 1963
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] IN order to carry out gut perfusion investigations on the components of liquid glucose it was necessary to isolate dextrose oligosaecharides in 50-g quantities. The charcoal-'Celite' column chromatographic technique of Whistler and Durso1 was applied to selected starch hydrolysates. Analysis of ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    CLARK, A. G. ; HITCHCOCK, MARGARET ; SMITH, J. N.

    [s.l.] : Nature Publishing Group
    Published 1966
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] We have attempted to identify such a metabolite in ticks, houseflies or locusts dosed with gammexane or in enzyme extracts fortified with glutathione, but have found the major metabolic product in each case to be an aromatized molecule which appears identical with S-(2,4-dichloro-phenyl) ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1434-6052
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract A study ofW ± andZ 0 properties has been performed using the UA2 detector at the $$\bar pp$$ collider. The data correspond to a total integrated luminosity of 142 nb−1 at $$\sqrt s $$ =546 GeV, and of 310 nb−1 at $$\sqrt s $$ =630 GeV. The experimental results are compared with the predictions of the Standard Model of the unified electroweak theory.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    1434-0879
    Keywords:
    Ureter ; Glucagon ; Propanolamines
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary The effects of 22 μg/kg/h glucagon and 240 μg/kg/h ritodrine infusions on the electrical activity and the intraluminal pressure of an acutely obstructed canine ureter have been studied. Acute obstruction of the ureter increased the rate of peristalsis from 7.05 (±0.61) to 19.87 (±0.47) per minute and the intraluminal pressure rose to a maximum of 124 cm water. Glucagon and ritodrine infusions reduced the rate of peristalsis to 6.32 (±0.73) and 5.83 (±0.84) respectively, whilst the intraluminal pressure was reduced by 43% during the glucagon infusion and 51% during the ritodrine infusion. The effect of ritodrine was more prolonged than that of glucagon.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1434-0879
    Keywords:
    Ureter ; Propanolamines
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Using an intact concious animal model the effect of various drugs on the rate of canine ureteric peristalsis was studied. The drugs found to reduce consistently the rate of ureteric peristalsis were diazoxide, terbutaline, and ritodrine. Ritodrine was the most consistent, having a prolonged effect and reducing the rate of ureteric peristalsis to 50% of the rates observed in control experiments.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    1432-198X
    Keywords:
    Lupus nephritis ; Acute tubular necrosis ; Azathioprine ; High-dose steroids
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    1434-6052
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract The UA2 experiment, running at the CERN SPS $$\bar pp$$ Collider, has performed a study of events containing three hard jets in the final state. The angular distributions of the three jets show evidence for gluon bremsstrahlung, in good agreement with a QCD model to leading order in the strong coupling constant αs. The yield of three-jet events relative to that of two-jet events provides a measure of the strong coupling constant: ;3 K 3/K 2=0.23±0.01±0.04, whereK 2 andK 3 represent the contributions arising from higher order corrections in α3 to the two- and three-jet exclusive cross-sections. A detailed discussion of the systematic and theoretical uncertainties is given.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    1434-6052
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract The production and properties of high transverse momentum hadron jets have been measured in the UA2 experiment at the CERN $$\bar pp$$ Collider $$(\sqrt s = 540 GEV)$$ using a highly segmented total absorption calorimeter. The characteristics of a sample of two-jet events with invariant mass up to 200 GeV/c2 are discussed, including measurements of their fragmentation properties, angular and rapidity distributions, and the properties of the additional energy clusters accompanying the two-jet system. Cross sections for inclusive jet production in the jet transverse momentum range between 30 and 100 GeV/c and for the two-jet invariant mass distribution in the mass range from 60–200 GeV/c2 are reported.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    1434-6052
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract The production of electrons with very high transverse momentum has been studied in the UA2 experiment at the CERN $$\bar pp$$ collider ( $$\sqrt s$$ =540 GeV). From a sample of events containing an electron candidate withp T 〉15 GeV/c, we extract a clear signal resulting from the production of the charged intermediate vector bosonW ±, which subsequently decays into an electron and a neutrino. We study theW production and decay properties. Further-more, we refine our results on the production and decay of the neutral vector bosonZ 0. Finally, we compare the experimental results to the predictions of the standard model of the unified electro-weak theory.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Staff View
    ISSN:
    1434-6052
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract Inclusive particle production cross-sections have been measured at the $$Sp\bar pS$$ collider using the UA2 detector in various ranges of transverse momentum (P T ) and pseudo-rapidity (η). Cross-section measurements are presented forπ 0 production (P T ≦15 GeV/c, |η|≦0.85 andP T ≦40 GeV/c, 1.0≦|η|≦1.8), for η meson production (3≦P T ≦6 GeV/c, |η|≦0.85) and for charged particle production (P T ≦10 GeV/c, 1.0≦|η|≦1.8). Results are compared with the predictions of QCD calculations.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1434-6052
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract We analyze the energy density distribution in harronic final states as a function of their total transverse energy measured in the segmented central calorimeter of the UA2 detector. The energy dependence of collective shape variables is investigated. The data, collected at the CERN $$\bar p$$ p Collider at $$\sqrt s = 630$$ GeV, exhibit strong variations in all these variables over the transverse energy range between 15 and 210 GeV, corresponding to substantial modifications in the structure of multihadronic final states. The evolution of the energy density distribution and of the collective shape variables shows a clear transition between two extreme dynamical regimes, respectively dominated byp T -limited phase space and by collimated two-jet configurations. A study of the relative populations of two-and three-jet systems reveals two different sources of configurations having three distinct lobes in the pattern of the energy-flow. A first component, steeply falling with energy, receives substantial contributions from soft parton collisions at lower transverse energies. Above 60 GeV a new hard component emerges, characterized by an approximately constant rate with respect to the dominant two-jet structures.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses