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1Latest Papers from Table of Contents or Articles in PressD. A. Landau ; E. Tausch ; A. N. Taylor-Weiner ; C. Stewart ; J. G. Reiter ; J. Bahlo ; S. Kluth ; I. Bozic ; M. Lawrence ; S. Bottcher ; S. L. Carter ; K. Cibulskis ; D. Mertens ; C. L. Sougnez ; M. Rosenberg ; J. M. Hess ; J. Edelmann ; S. Kless ; M. Kneba ; M. Ritgen ; A. Fink ; K. Fischer ; S. Gabriel ; E. S. Lander ; M. A. Nowak ; H. Dohner ; M. Hallek ; D. Neuberg ; G. Getz ; S. Stilgenbauer ; C. J. Wu
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-10-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Transformation, Neoplastic/genetics ; Clone Cells/metabolism/pathology ; DNA Copy Number Variations/genetics ; *Disease Progression ; *Evolution, Molecular ; Exome/genetics ; Genes, myc/genetics ; Humans ; Ikaros Transcription Factor/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis/*genetics/pathology/therapy ; MAP Kinase Signaling System/genetics ; Mutation/*genetics ; Neoplasm Recurrence, Local/*genetics ; Prognosis ; RNA Processing, Post-Transcriptional/genetics ; RNA Transport/genetics ; Ribosomal Proteins/genetics ; Treatment OutcomePublished by: -
2Latest Papers from Table of Contents or Articles in PressBendell, J. C., Varghese, A. M., Hyman, D. M., Bauer, T. M., Pant, S., Callies, S., Lin, J., Martinez, R., Wickremsinhe, E., Fink, A., Wacheck, V., Moore, K. N.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-07-17Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The β-diketonate process for chemical vapor deposition Y1Ba2Cu3O6.5+x is extended to deposition on enlarged areas up to 20 cm2. The films are prepared on monocrystalline SrTiO3 and reveal a surface topography comparable to films by laser ablation. The inductively measured transition temperature Tc is up to 93 K and the transition width is smaller than 1 K; Tc is well reproduced from run to run. The critical current density jc at 77 K attains values as high as 6×106 A/cm2 in zero magnetic field; the current carrying capacity in magnetic fields up to 8 T is presented.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesFink, A. ; Huber, R. ; Widdra, W.
College Park, Md. : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Ethylene adsorption on vicinal, single-domain Ge(100)-(2×1) has been investigated by thermal desorption spectroscopy (TPD) and angle-resolved photoemission (ARUPS) using linearly polarized synchrotron radiation. Thermal desorption experiments show that chemisorbed C2H4 desorbs from Ge(100) nondissociatively around 393 K with a high temperature shoulder which is tentatively assigned to step site desorption. The ethylene saturation coverage is strongly temperature dependent. Adsorption at 90 K saturates at 0.38 monolayer (ML), whereas adsorption at 170 K leads to a saturation coverage of approximately 1 ML. This behavior is explained by an adsorption barrier for coverages exceeding 0.38 ML. ARUP spectra for a dilute and the saturated ethylene monolayer reveal clear differences. Using photoemission selection rules a highly (C2v) symmetric adsorption geometry with a C–C bond axis parallel to the Ge–Ge dimer axis is found for the dilute layer; whereas a reduced C2 adsorption symmetry is found for the saturated ethylene layer. The comparison of photoemission spectra for C2H4 on Ge(100) and Si(100) shows that C2H4 is di-σ bound to the dangling bonds of a single Ge–Ge dimer. For two molecular orbitals, 1b3u and 1b2g, one-dimensional band structures with dispersion widths of 0.5 and 0.39 eV, respectively, along the Ge–Ge dimer rows are found which present a straightforward explanation for the observed symmetry reduction and adsorption behavior. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesTOKARSKA-SCHLATTNER, M. ; FINK, A. ; CASTILLO, F. J. ; CRESPI, P. ; CREVECOEUR, M. ; GREPPIN, H. ; TACCHINI, P.
Oxford, UK : Blackwell Publishing Ltd
Published 1997Staff ViewISSN: 1365-3040Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: The protein pattern of leaf plasma membranes from Arabidopsis thaliana (L.) Landsberg erecta was analysed in order to detect changes induced by acute short-term ozone treatment. Plasma membranes were isolated 0, 3 and 8 h after the end of a 2 h fumigation of the plants with 500 nmol mol−1 of O3. Proteins extracted from plasma membranes were separated by high-performance two-dimensional polyacrylamide gel electrophoresis. Eight hours after the end of fumigation, one new protein appeared and the amounts of two other proteins increased significantly. The reported study is a first step towards the identification of plasmalemma proteins altered by ozone and to a more detailed characterization of structural changes occurring in the plasma membrane after ozone exposure.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesWEISMAN, Z. ; FINK, A. ; ALON, A. ; POLIAK, Z. ; TABACHNIK, E. ; PRISCU, L. ; BENTWICH, Z.
Oxford, UK : Blackwell Publishing Ltd
Published 1990Staff ViewISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: In the present study we assessed the effect of leukotriene C4 on ciliary beat frequency in vitro. Chicken tracheas were sliced into thin rings and ciliary activity was viewed microscopically. Ciliary beat frequency was measured through an optical fibre by a fast Fourier transformer analyser and recorded on an oscilloscope. Ciliary beat frequency was measured at one fixed point during 30 min at room temperature in RPMI-HEPES medium alone and in medium containing leukotriene C4 at a range of concentrations (10−6–10−9M). Our results demonstrate that leukotriene C4(10−7 and 10−8M) caused a significant decrease in ciliary beat frequency in all tracheal rings tested (mean decrease of 24%). The specificity and Ca2+ -dependency of leukotriene C4 activity was elucidated by the ability of FPL 55712 (SRS-A specific antagonist), Ca2+ -free medium, calcium channel blockers (nifedipine and verapamil) and the calmodulin inhibitor trifluroperazine to abrogate its effect on ciliary beating.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesFink, A. S. ; Egnor, R. W. ; Kazandjian, G. ; La Morte, G. ; Klonsky, K.
Oxford, UK : Blackwell Publishing Ltd
Published 1985Staff ViewISSN: 1600-0714Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The effect of the increasing degree of human gingival inflammation on adenylate cyclase (basal, fluoride stimulated) and low Km and high Km cAMP phosphodiesterase activities were evaluated in separate studies. Human gingival biopsies were classified by the Löe Bleeding Index as (1) mildly, (2) moderately, and (3) markedly inflamed. Basal and F stimulated adenylate cyclase (cAMP synthesis) activities were found to be unaltered by the increasing degree of inflammation when the data were expressed on either a mg wet wt, or mg protein basis. A significant loss of F stimulated adenylate cyclase (mg protein) activity was observed in the moderately inflamed group when the data were compared with either the mildly or markedly inflamed groups of tissue. The low Km, and high Km cAMP phosphodiesterase activities (cAMP degradation) were found to he unaffected by gingival inflammation. This suggests that neither cAMP synthesis, nor degradation are stimulated in human gingiva by inflammation.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesBRODISH, R. J. ; KUVSHINOFF, B. W. ; FINK, A. S. ; McFadden, D. W. ; TURKELSON, J. ; SOLOMON, T. E.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesBRODISH, R. J. ; KUVSHINOFF, B. W. ; FINK, A. S. ; TURKELSON, J. ; McFADDEN, D. W. ; SOLOMON, T. E.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesFöhlisch, A. ; Feulner, P. ; Hennies, F. ; Fink, A. ; Menzel, D. ; Sanchez-Portal, D. ; Echenique, P. M. ; Wurth, W.
[s.l.] : Macmillian Magazines Ltd.
Published 2005Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Dynamical processes are commonly investigated using laser pump–probe experiments, with a pump pulse exciting the system of interest and a second probe pulse tracking its temporal evolution as a function of the delay between the pulses. Because the time resolution attainable in such ...Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0149-7189Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicinePsychologySociologyType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0022-2828Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0309-1651Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesTacchini, P. ; Fink, A. ; Thiellement, H. ; Greppin, H.
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Late flowering monogenic mutants of Arabidopsis thaliana (L.) Heynh. at the loci co, gi, fca, fve, fwa, fha, fpa, fy and their corresponding wild type, Landsberg erecta, were analysed by two-dimensional gel electrophoresis. All plants were grown under continuous light and proteins were extracted from leaves of the same age (20-day-old). The polypeptide patterns of the mutants at the loci co, gi, fca, fve, fwa, fha, fpa, and Landsberg erecta were identical. The mutant at the fy locus showed a qualitative difference with Landsberg erecta. Crosses were made between this line and the wild type Landsberg erecta. F2 plants, resulting from autopollination of the hybrid, were analysed and showed no cosegregation between the observed protein and the flowering phenotype, indicating that these two lines differ by more than a single mutation.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1436-5081Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1570-1468Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringNotes: Conclusions 1. The installation of a conical transitional segment between a tower (shaft)-type water intake-outlet and penstock affects a significant reduction in head loss in the pump mode, but has virtually no effect on the magnitude of the latter in the pump mode. 2. The existence of a conical transitional element in the pump mode appreciably lowers the discharge velocities of the flow and increases the effective height of the water-passing openings by 1.5–1.7 times when the height of the intake openings h≥0.5dp. 3. The head losses in the intake-outlet decrease in the pump mode of operation with increasing degree of expansion of the transitional diffusor segment.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1434-4475Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1420-8903Keywords: Primary 26D15, 26D20Source: Springer Online Journal Archives 1860-2000Topics: MathematicsNotes: Summary We investigate generalizations of the classical Jensen and Chebyshev inequalities. On one hand, we restrict the class of functions and on the other we enlarge the class of measures which are allowed. As an example, consider the inequality (J)ϕ(∫f(x) dμ) ⩽ A ∫ ϕ(f(x) dμ, d∫ dμ = 1. Iff is an arbitrary nonnegativeL x function, this holds ifμ ⩾ 0,ϕ is convex andA = 1. Iff is monotone the measure μ need not be positive for (J) to hold for all convex ϕ withA = 1. If ϕ has higher monotonicity, e.g., ϕ′ is also convex, then we get a version of (J) withA 〈 1 and measures μ that need not be positive.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1570-1468Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringType of Medium: Electronic ResourceURL: