Search Results - (Author, Cooperation:A. E. Williams)
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1Latest Papers from Table of Contents or Articles in PressFleming-Davies, A. E., Williams, P. D., Dhondt, A. A., Dobson, A. P., Hochachka, W. M., Leon, A. E., Ley, D. H., Osnas, E. E., Hawley, D. M.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-03-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Epidemiology, EvolutionPublished by: -
2Latest Papers from Table of Contents or Articles in PressA. Sinha ; K. R. Hughes ; K. K. Modrzynska ; T. D. Otto ; C. Pfander ; N. J. Dickens ; A. A. Religa ; E. Bushell ; A. L. Graham ; R. Cameron ; B. F. Kafsack ; A. E. Williams ; M. Llinas ; M. Berriman ; O. Billker ; A. P. Waters
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-02-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Culicidae/parasitology ; DNA-Binding Proteins/deficiency/genetics/*metabolism ; Feedback, Physiological ; Female ; Gene Expression Regulation ; Germ Cells/cytology/*growth & development/metabolism ; Malaria/*parasitology ; Male ; Mutation/genetics ; Plasmodium berghei/cytology/*genetics/*physiology ; Protein Transport ; Protozoan Proteins/genetics/*metabolism ; Reproduction, Asexual ; Sexual Development/*genetics ; Transcription, GeneticPublished by: -
3Latest Papers from Table of Contents or Articles in PressB. F. Kafsack ; N. Rovira-Graells ; T. G. Clark ; C. Bancells ; V. M. Crowley ; S. G. Campino ; A. E. Williams ; L. G. Drought ; D. P. Kwiatkowski ; D. A. Baker ; A. Cortes ; M. Llinas
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-02-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; DNA-Binding Proteins/deficiency/genetics/metabolism ; Female ; Gene Expression Regulation/*genetics ; Gene Silencing ; Genes, Protozoan/genetics ; Genome, Protozoan/genetics ; Germ Cells/cytology/*growth & development/metabolism ; Malaria/*parasitology ; Male ; Parasites/cytology/genetics/*physiology ; Plasmodium falciparum/cytology/*genetics/physiology ; Protozoan Proteins/genetics/metabolism ; Reproduction, Asexual ; Sex Differentiation/genetics ; Sexual Development/*genetics ; Transcription, Genetic/*geneticsPublished by: -
4Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Scanning electron microscopy has been used to study normal and abnormal cervical epithelia. Normal columnar epithelium and normal squamous epithelium have been identified and described. Carcinoma in situ has also been examined and characteristic differences in tissue organization and cell morphology have been recognized. The surfaces of normal squamous cells are arranged with interconnecting microridges, whereas the surface epithelium from carcinoma in situ cells is arranged in closly packed microvilli. The significance of these results and the possible potential of the technique in studying the natural history of carcinoma in situ are discussed.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: A measurement of the effect of mildew and leaf blotch on both yield and quality of Lolium multiflorum (cv. Lior) was undertaken in two trials sown in 1966 and 1967.Plots were sprayed with a fungicide at 10-day intervals, and four cuts were taken during the season. Disease assessments were made at the time of cutting. Considerable differences in yield and quality were recorded which could be broadly related to the levels of disease infection in the treatments.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesMaskell, D. J. ; Szabo, M. J. ; Butler, P. D. ; Williams, A. E. ; Moxon, E. R.
Oxford, UK : Blackwell Publishing Ltd
Published 1991Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: A chromosomal locus, lic3, one of several involved in lipopolysaccharide (LPS) biosynthesis by Haemophilus influenzae, was cloned and its DNA sequence determined. Iic3 comprises four closely apposed open reading frames (ORFs). ORF1 includes tandem repeats of the tetramer CAAT and two start codons out of frame with each other are found upstream of the repeats. ORF1 encodes a protein with no known homologues. 0RF2 encodes the UDP-galactose-4-epimerase (galE) gene. ORF3 encodes a hydrophobic protein with no known homologues. 0RF4 encodes the adenylate kinase (adk) gene. A deletion/insertion mutation lacking the 3′ end of ORF1, all of galE, and the 5′ end of ORF3 was constructed in the parent Hib strain (RM7004). These mutants had a galE phenotype, as evidenced by galactose sensitivity, altered LPS when grown in the absence of exogenous galactose, and reduced virulence in infant rats.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Ions which dissociate during their transit of a mass spectrometer analyser tube are said to be meta-stable1. They are noted on the mass scale of the spectrum at a position corresponding to m*, where: mx i 4. 1 -j r ) and Wi is the mass of the ion before dissociation, mz is the mass of the ...Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesSMITH, H. ; WILLIAMS, A. E. ; PEARCE, J. H. ; KEPPIE, J. ; HARRIS-SMITH, P. W. ; FITZ-GEORGE, R. B. ; WITT, K.
[s.l.] : Nature Publishing Group
Published 1962Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] IN brucellosis of pregnant cows, the predilection of Brucella abortus for foetal rather than adult tissue is well known1. General pathological findings have indicated an especially heavy infection in the foetal cotyledons (placental tissue), the chorion and the purulent foetal fluids2'3, and we ...Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 0035-1466Topics: Linguistics and Literary StudiesNotes: Notes et DocumentsURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1432-0533Keywords: Key words Monocyte ; Scrapie ; Central nervous ; system ; PathogenesisSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The recruitment of monocytes into the scrapie-affected brain was investigated in female mice reconstituted with male bone marrow, using a Y-chromosome-specific probe and F4/80 immunocytochemistry. Recruitment of monocytes could be demonstrated in six out of eight animals and the number of recruited cells correlated with the severity of vacuolation in most, but not all, animals. The proportion of microglia derived from recruited monocytes varied between individual animals, did not correlate with the increase in cellularity (glia) in affected areas of brain and did not affect the length of incubation period. Thus, it is unlikely that the recruitment of monocytes is a pivotal event in the development of early pathological changes in scrapie. The morphology of recruited cells in scrapie lesions, as revealed by F4/80 immunoreactivity, was indistinguishable from that of activated resident microglia.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1432-0533Keywords: Monocyte ; Scrapie ; Central nervous system ; PathogenesisSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The recruitment of monocytes into the scrapie-affected brain was investigated in female mice reconstituted with male bone marrow, using a Y-chromosome-specific probe and F4/80 immunocytochemistry. Recruitment of monocytes could be demonstrated in six out of eight animals and the number of recruited cells correlated with the severity of vacuolation in most, but not all, animals. The proportion of microglia derived from recruited monocytes varied between individual animals, did not correlate with the increase in cellularity (glia) in affected areas of brain and did not affect the length of incubation period. Thus, it is unlikely that the recruitment of monocytes is a pivotal event in the development of early pathological changes in scrapie. The morphology of recruited cells in scrapie lesions, as revealed by F4/80 immunoreactivity, was indistinguishable from that of activated resident microglia.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] We have chosen to study the attachment of tumour cells to the diaphragms of hooded rats. Diaphragms were removed from normal rats and from rats carrying ascites tumour cells (WBPl) (ref. 1). Pieces were mounted on clamp stubs, peritoneum side upward, and either left unwashed or gently washed with ...Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1076-5174Keywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyPhysicsNotes: Certain of the “meta-stable peaks” in mass spectra are abnormally wide. This extra width is shown to be associated with release of kinetic energy during fragmentation. Methods are presented for measuring this energy release and values are given for various transitions in the spectra of aromatic nitro compounds.Additional Material: 3 Ill.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0030-493XKeywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: The mass spectra of guanidine and ten of its derivatives have been studied under both high and low resolution conditions. Evidence was detected for the migration of methyl groups, the formation of intermediate three-membered ring structures and decompositions involving expulsion of N. with release of kinetic energy.Additional Material: 13 Ill.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0030-493XKeywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Benzene, toluene, phenol, diphenyl ether and the three isomeric dihydroxy-benzenes have been examined using an MS-9 mass spectrometer under conditions that allowed only ions having twice the normal amount of kinetic energy to be detected. These ions are, in fact, singly charged ions arising from charge exchange reactions of doubly charged ions of the same mass, occuring in the first field free region of the Spectrometer. It is argued that the spectra obtained yield essentially the distribution of doubly charged ions in the source region. These ‘doubly charged ion’ mass spectra are compared with the normal singly charged ion spectra of the compounds and the implications of the significant differences that are found, are discussed.Additional Material: 4 Ill.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0030-493XKeywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesGoldberg, P. ; Hopkinson, J. A. ; Mathias, A. ; Williams, A. E.
Chichester : Wiley-Blackwell
Published 1970Staff ViewISSN: 0030-493XKeywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: The n-alkanes, propane to heptane, have been studied in a modified MS-9 mass spectrometer under conditions that enabled the daughter ions, resulting from metastable fragmentation processes occurring in the first field free region, to be observed with high sensitivity. The precursor ions in these fragmentations have been identified unambiguously and a general fragmentation scheme for the n-alkanes is proposed. The mass spectrometer incorporated a variable width monitor slit and narrow settings of this slit improved the energy resolution so that fine structure could be observed in some of the ‘metastable peaks’. The implications of this fine structure are discussed.Additional Material: 3 Ill.Type of Medium: Electronic ResourceURL: