Search Results - (Author, Cooperation:A. Dityatev)
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1Latest Papers from Table of Contents or Articles in PressM. Caiazzo ; M. T. Dell'Anno ; E. Dvoretskova ; D. Lazarevic ; S. Taverna ; D. Leo ; T. D. Sotnikova ; A. Menegon ; P. Roncaglia ; G. Colciago ; G. Russo ; P. Carninci ; G. Pezzoli ; R. R. Gainetdinov ; S. Gustincich ; A. Dityatev ; V. Broccoli
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Action Potentials ; Animals ; Animals, Newborn ; Basic Helix-Loop-Helix Transcription Factors/genetics/metabolism ; *Cell Differentiation/genetics/physiology ; Cells, Cultured ; *Cellular Reprogramming/genetics/physiology ; Dopamine/*metabolism/secretion ; Embryo, Mammalian/cytology ; Fibroblasts/*cytology/metabolism ; Gene Expression Profiling ; Homeodomain Proteins/genetics/metabolism ; Humans ; LIM-Homeodomain Proteins ; Mice ; Neurons/*cytology/*metabolism/secretion ; Nuclear Receptor Subfamily 4, Group A, Member 2/genetics/metabolism ; Oligonucleotide Array Sequence Analysis ; Parkinson Disease/pathology ; Patch-Clamp Techniques ; Regenerative Medicine ; Skin/cytology ; Transcription FactorsPublished by: -
2Latest Papers from Table of Contents or Articles in PressMichels, B., Zwaka, H., Bartels, R., Lushchak, O., Franke, K., Endres, T., Fendt, M., Song, I., Bakr, M., Budragchaa, T., Westermann, B., Mishra, D., Eschbach, C., Schreyer, S., Lingnau, A., Vahl, C., Hilker, M., Menzel, R., Kähne, T., Lessmann, V., Dityatev, A., Wessjohann, L., Gerber, B.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-10-25Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1573-9007Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract This article compares four models of amplitude fluctuations in postsynaptic potentials. The convolution of two binomial distributions and the beta model proved the best fit with experimentally obtained data (as compared with the binomial model). The beta model is based on the assumption that the probability of quantal transmitter release is a random variable with a beta distribution. Numbers of quantal generators as estimated by the beta model were found to resemble numbers of morphological identifiable synaptic boutons. Findings from research using this model showed that the binomial parameter n may be interpreted as the number of transmitter release sites functioning with a probability in excess of 0.2. The findings obtained confirm the postulated functional diversity of release sites at interneuronal synapses.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 1573-9007Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Discrete distributions of amplitude of basic EPSP in vertebrate interneuronal synapses were obtained using the maximum likelihood method. Unequal intervals found between the values of calculated densities indicate the quantal nature of the signal. It was shown that quantal levels of nerve impulse transmission due to the structural arrangement of interneuronal connections may be distinguished using a binomial model, approximating as it does to empirical distributions. Systematic discrepancies between empirical and modeled distributions indicate the need to extend the model, however.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1573-9007Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Analysis of discrete distributions of basic EPSP amplitudes at sensorimotor, proprio- and reticulo-motoneuronal synapses in the frog by means of the convolution of two binomial distributions revealed that the number of transmitter release sites operating was greater than that calculated by means of binomial distribution. Probability levels of transmitter release sites responding in unison to nerve impulses are dissimilar (at not more than 0.1–0.3) and remained constant. Interference with the release mechanism induced blockade of release sites. Impairment of the process triggering transmitter release produced a sharp decline in the probability of release sites operating in unison.Type of Medium: Electronic ResourceURL: