Search Results - (Author, Cooperation:A. C. Martin)
-
1Latest Papers from Table of Contents or Articles in PressB. Chaneton ; P. Hillmann ; L. Zheng ; A. C. Martin ; O. D. Maddocks ; A. Chokkathukalam ; J. E. Coyle ; A. Jankevics ; F. P. Holding ; K. H. Vousden ; C. Frezza ; M. O'Reilly ; E. Gottlieb
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-10-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Line, Tumor ; Cell Proliferation ; Enzyme Activation/drug effects ; Enzyme Activators/pharmacology ; Glucose/metabolism ; Glycine/metabolism/pharmacology ; Humans ; *Ligands ; Pyruvate Kinase/genetics/*metabolism ; Pyruvic Acid/metabolism ; Recombinant Proteins/metabolism ; Serine/*metabolism/pharmacologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2015-01-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Apoptosis ; *Cell Polarity ; Drosophila melanogaster/*cytology/*embryology ; Epithelial Cells/*cytology ; Epithelium/*embryology ; *MorphogenesisPublished by: -
3Latest Papers from Table of Contents or Articles in PressBhuiyan, M. U., Snelling, T. L., West, R., Lang, J., Rahman, T., Borland, M. L., Thornton, R., Kirkham, L.-A., Sikazwe, C., Martin, A. C., Richmond, P. C., Smith, D. W., Jaffe, A., Blyth, C. C.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-03-17Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Respiratory medicine, EpidemiologyPublished by: -
4Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-04-26Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: palaeontology, evolutionPublished by: -
5Latest Papers from Table of Contents or Articles in PressM. A. Lancaster ; M. Renner ; C. A. Martin ; D. Wenzel ; L. S. Bicknell ; M. E. Hurles ; T. Homfray ; J. M. Penninger ; A. P. Jackson ; J. A. Knoblich
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-09-03Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Brain/anatomy & histology/cytology/*growth & development/*pathology ; Cerebral Cortex/cytology/embryology/growth & development/pathology ; Humans ; Induced Pluripotent Stem Cells/cytology/pathology ; Mice ; Microcephaly/*pathology ; *Models, Biological ; Neural Stem Cells/cytology/pathology ; Neurogenesis ; Neurons/cytology/pathology ; Organoids/*cytology/embryology/*growth & development/pathology ; Tissue Culture Techniques/*methodsPublished by: -
6Articles: DFG German National LicensesWadhams, G. H. ; Martin, A. C. ; Porter, S. L. ; Maddock, J. R. ; Mantotta, J. C. ; King, H. M. ; Armitage, J. P.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: TlpC is encoded in the second chemotaxis operon of Rhodobacter sphaeroides. This protein shows some homology to membrane-spanning chemoreceptors of many bacterial species but, unlike these, is essential for R. sphaeroides chemotaxis to all compounds tested. Genomic replacement of tlpC with a C-terminal gfp fusion demonstrated that TlpC localized to a discrete cluster within the cytoplasm. Immunogold electron microscopy also showed that TlpC localized to a cytoplasmic electron-dense region. Correct TlpC–GFP localization depended on the downstream signalling proteins, CheW3, CheW4 and CheA2, and was tightly linked to cell division. Newly divided cells contained a single cluster but, as the cell cycle progressed, a second cluster appeared close to the initial cluster. As elongation continued, these clusters moved apart so that, on septation, each daughter cell contained a single TlpC cluster. The data presented suggest that TlpC is either a cytoplasmic chemoreceptor responding to or integrating global signals of metabolic state or a novel and essential component of the chemotaxis signalling pathway. These data also suggest that clustering is essential for signalling and that a mechanism may exist for targeting and localizing proteins within the bacterial cytoplasm.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesWadhams, G. H. ; Warren, A. V. ; Martin, A. C. ; Armitage, J. P.
Oxford, UK : Blackwell Publishing Ltd
Published 2003Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: Components of bacterial chemosensory pathways which sense via transmembrane receptors have been shown to localize to the cell poles. Many species, however, have operons encoding multiple putative chemosensory pathways, some including putative cytoplasmic receptors. In-genome fusions to single or multiple genes encoding components of two chemosensory pathways in Rhodobacter sphaeroides, cheOp2 and cheOp3, revealed that while sensory transducing proteins associated with transmembrane receptors and encoded on cheOp2 were targeted to the cell poles, the proteins associated with putative cytoplasmic receptors and encoded on cheOp3 were all targeted to a cytoplasmic cluster. No proteins were localized to both sites. These data show that bacteria target components of related pathways to different sites in the cell, presumably preventing direct cross-talk between the different pathways, but allowing a balanced response between extracellular and cytoplasmic signals. It also indicates that there is intracellular organization in bacterial cells, with specific proteins targeted and localized to cytoplasmic regions.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Our work used gelatine gum arabic and haemoglobin-gum arabic coacervates prepared by a method similar to that reported by Dervichian5. To prepare the gelatine coacervates, equal volumes of 1 per cent solutions of gelatine and gum arabic were mixed and brought to a pH range of 2-5-4-0 by adding ...Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] UNDER the above heading in NATURE of July 10, p. 49, Dr. C. W. Stiles gives a summary of the argument in support of a proposition to re-open the case of Simia before the International Commission on Zoological Nomenclature. Although in agreement with most of the general principles enumerated in ...Type of Medium: Electronic ResourceURL: