Search Results - (Author, Cooperation:A. Burt)

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  1. 1
  2. 2
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2014-01-25
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cell Lineage/*genetics ; Dog Diseases/*genetics ; Dogs/*genetics ; Founder Effect ; Gene Dosage ; Genome ; Karyotype ; Mutation ; Retroelements ; Venereal Tumors, Veterinary/*epidemiology/*genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    D. E. Neafsey ; R. M. Waterhouse ; M. R. Abai ; S. S. Aganezov ; M. A. Alekseyev ; J. E. Allen ; J. Amon ; B. Arca ; P. Arensburger ; G. Artemov ; L. A. Assour ; H. Basseri ; A. Berlin ; B. W. Birren ; S. A. Blandin ; A. I. Brockman ; T. R. Burkot ; A. Burt ; C. S. Chan ; C. Chauve ; J. C. Chiu ; M. Christensen ; C. Costantini ; V. L. Davidson ; E. Deligianni ; T. Dottorini ; V. Dritsou ; S. B. Gabriel ; W. M. Guelbeogo ; A. B. Hall ; M. V. Han ; T. Hlaing ; D. S. Hughes ; A. M. Jenkins ; X. Jiang ; I. Jungreis ; E. G. Kakani ; M. Kamali ; P. Kemppainen ; R. C. Kennedy ; I. K. Kirmitzoglou ; L. L. Koekemoer ; N. Laban ; N. Langridge ; M. K. Lawniczak ; M. Lirakis ; N. F. Lobo ; E. Lowy ; R. M. MacCallum ; C. Mao ; G. Maslen ; C. Mbogo ; J. McCarthy ; K. Michel ; S. N. Mitchell ; W. Moore ; K. A. Murphy ; A. N. Naumenko ; T. Nolan ; E. M. Novoa ; S. O'Loughlin ; C. Oringanje ; M. A. Oshaghi ; N. Pakpour ; P. A. Papathanos ; A. N. Peery ; M. Povelones ; A. Prakash ; D. P. Price ; A. Rajaraman ; L. J. Reimer ; D. C. Rinker ; A. Rokas ; T. L. Russell ; N. Sagnon ; M. V. Sharakhova ; T. Shea ; F. A. Simao ; F. Simard ; M. A. Slotman ; P. Somboon ; V. Stegniy ; C. J. Struchiner ; G. W. Thomas ; M. Tojo ; P. Topalis ; J. M. Tubio ; M. F. Unger ; J. Vontas ; C. Walton ; C. S. Wilding ; J. H. Willis ; Y. C. Wu ; G. Yan ; E. M. Zdobnov ; X. Zhou ; F. Catteruccia ; G. K. Christophides ; F. H. Collins ; R. S. Cornman ; A. Crisanti ; M. J. Donnelly ; S. J. Emrich ; M. C. Fontaine ; W. Gelbart ; M. W. Hahn ; I. A. Hansen ; P. I. Howell ; F. C. Kafatos ; M. Kellis ; D. Lawson ; C. Louis ; S. Luckhart ; M. A. Muskavitch ; J. M. Ribeiro ; M. A. Riehle ; I. V. Sharakhov ; Z. Tu ; L. J. Zwiebel ; N. J. Besansky
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-01-03
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Anopheles/classification/*genetics ; Base Sequence ; Chromosomes, Insect/genetics ; Drosophila/genetics ; *Evolution, Molecular ; *Genome, Insect ; Humans ; Insect Vectors/classification/*genetics ; Malaria/*transmission ; Molecular Sequence Data ; Phylogeny ; Sequence Alignment
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2015-08-01
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; CRISPR-Cas Systems ; *Clustered Regularly Interspaced Short Palindromic Repeats ; *Containment of Biohazards ; Endonucleases/metabolism ; *Genetic Engineering ; *Genetic Research ; Genome ; *Organisms, Genetically Modified ; *Safety
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Alex Kluber, Timothy A. Burt, Cecilia Clementi
    National Academy of Sciences
    Published 2018
    Staff View
    Publication Date:
    2018-09-12
    Publisher:
    National Academy of Sciences
    Print ISSN:
    0027-8424
    Electronic ISSN:
    1091-6490
    Topics:
    Biology
    Medicine
    Natural Sciences in General
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    C. A. Rebbeck ; A. M. Leroi ; A. Burt
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-01-22
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Coyotes/genetics ; Dog Diseases/*genetics/metabolism/pathology ; Dogs/genetics ; Gene Transfer, Horizontal ; *Genome, Mitochondrial ; *Mitochondria/genetics/metabolism ; Phylogeny ; Polymorphism, Genetic ; Selection, Genetic ; Sequence Analysis, DNA ; Venereal Tumors, Veterinary/*genetics/*metabolism/pathology ; Wolves/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2011-04-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Animals, Genetically Modified ; Anopheles gambiae/*genetics ; Deoxyribonucleases, Type II Site-Specific/genetics ; Female ; Genes, Reporter/genetics ; *Genetic Engineering ; Genotype ; Insect Vectors/*genetics ; Male ; Molecular Sequence Data ; Mosquito Control/*methods ; Saccharomyces cerevisiae Proteins/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Burt, A. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1977
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract— Choline kinase (ATP:cholinephosphotransferase; EC 2.7.1.32) activity was measured in preparations of lumbar spinal cord from rats ranging in development from 12 days of gestation to 46 days of age. The enzyme activity was measured with a radiochemical assay procedure suitable for whole tissue preparations which are rich in ATP-metabolizing enzymes. Total choline kinase activity was further differentiated into hemicholinium-3 (HC-3) sensitive and HC-3 insensitive components. The specific activity of choline kinase (unhibited) increased 3-fold during the prenatal period and subsequently decreased to relatively low levels by birth. There was no significant change in choline kinase activity throughout the postnatal period. The ontogenetic patterns for the HC-3 sensitive and HC-3 insensitive components of choline kinase activity had transient peaks in activity during the prenatal period; however, these peaks in specific activity for the 2 components were 2–3 days out of phase temporally. HC-3 insensitive activity reached a peak at 18 days of gestation while the HC-3 sensitive activity peaked at 2CL21 days of gestation. In the 10-day-old rat, the apparent choline Km values were 0.56 and 0.16 MM for the total activity, 0.58 and 0.13 mM for the HC-3 insensitive activity, and 0.47 for the HC-3 sensitive activity.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    El-Refaie, A M Ahmed ; Burt, A D

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Aims : The pathogenesis of rejection following liver transplantation is not fully understood. It has been postulated that mast cells may play a role in acute and chronic rejection of a number of other solid organ grafts. The aim of this study was to assess the possible role of mast cells and c-Kit+ cells in acute and chronic liver allograft rejection.Methods and results : Biopsy specimens from (i) ‘time zero’ grafts with a minimal degree of perfusion injury (controls), (ii) transplanted livers with different grades of acute rejection, and (iii) transplanted livers with end-stage chronic rejection, were stained immunohistochemically using monoclonal anti-mast cell tryptase and polyclonal anti-c-Kit antibodies. Tryptase- and c-Kit-positive cell densities were assessed by image analysis. Tryptase-postive mast cell densities (P 〈 0.001) were strongly correlated with acute liver allograft rejection grades and chronic liver allograft rejection. Furthermore, a similarly strong relationship was found between c-Kit+ cell densities and increasing rejection grade (P 〈 0.001).Conclusions : Tryptase- and c-Kit-positive mast cells form part of the inflammatory infiltrate in both acute and chronic liver allograft rejection, and may be important effector cells in these processes.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    BURT, A. ; GOUDIE, R. B.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1979
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Thyroglobulin was found by the immunoperoxidase technique in routine histological sections of biopsies from all of 30 proven cases of well differentiated papillary or follicular thyroid carcinoma examined, in one of 20 anaplastic thyroid tumours and in none of 49 other tumours examined. Immunohistological demonstration of thyroglobulin in thyroidal or extrathyroidal tumours is of diagnostic value in confirming that the thyroid is the tissue of origin. Well differentiated tumours lacking thyroglobulin probably do not arise from thyroid epithelium.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Burt, A D

    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Published 1999
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Koeppen, H K W ; Wright, B D ; Burt, A D ; Quirke, P ; McNicol, A M ; Dybdal, N O ; Sliwkowski, M X ; Hillan, K J

    Oxford, UK : Blackwell Science Ltd
    Published 2001
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Using a standardized immunohistochemical assay we have evaluated 575 primary neoplasms of different histogenesis to determine the incidence of HER2 overexpression in some of the most common categories of human solid neoplasms. This study addresses the variable incidence of HER2 overexpression previously published for some tumour types.〈section xml:id="abs1-2"〉〈title type="main"〉Methods and results:The immunohistochemical staining was performed on paraffin sections of surgical specimens and a well-defined scoring system based upon numbers of HER2 receptors expressed on the cell surface was applied. Overexpression of HER2 as defined as a HER2 score of equal or greater than 2 was seen in breast cancer (22%), pulmonary adenocarcinoma (28%), colorectal adenocarcinomas (17%), pulmonary squamous (11%) and gastric adenocarcinomas (11%). As expected, the proportion of cases with a HER2 score of 3 was highest in breast cancer. Contrary to published results prostate and pancreas adenocarcinomas showed a very low incidence of HER2 overexpression.〈section xml:id="abs1-3"〉〈title type="main"〉Conclusions:Overexpression of HER2 is detected immunohistochemically in a proportion of epithelial neoplasms of diverse histogenesis in addition to ductal breast cancer. The standardized format of the assay will allow comparative analyses of studies performed at different institutions.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Courtier, Burt A.

    Tokyo : Periodicals Archive Online (PAO)
    Published 1994
    Articles: DFG German National Licenses
  16. 16
    Aithal, G. P. ; Haugk, B. ; Das, S. ; Card, T. ; Burt, A. D. ; Record, C. O.

    Oxford, UK : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background : Reports that up to 26% of subjects with psoriasis develop cirrhosis have led to a recommendation of serial liver biopsies after each cumulative dose of 1500 mg of methotrexate.Aim : To evaluate the progression of liver injury in patients with psoriasis and the impact of monitoring by liver biopsy on their management.Methods : One hundred and twenty-one liver biopsies from 66 subjects (aged 11–79 years) with psoriasis, receiving a median cumulative dose of 3206 mg of methotrexate over a period of 280.5 weeks, were evaluated.Results : The assessment of advanced fibrosis according to the Ishak system (≥ 4) correlated perfectly with that of the Scheuer system (≥ 3) and poorly with that of the Roenigk scale (≥ 3b) (r2 = 1.0 and 0.31, respectively). Two of 24 pre-treatment biopsies showed advanced fibrosis and both subjects were heavy drinkers. The cumulative probabilities of advanced fibrosis (Ishak ≥ 4) were 0%, 2.6%, 2.6%, 8.2% and 8.2% at cumulative doses of 1500, 3000, 4500, 5000 and 6000 mg, respectively. None of the subjects developed cirrhosis during follow-up or discontinued therapy on the basis of liver biopsy findings.Conclusions : Advanced hepatic fibrosis with low-dose methotrexate therapy is much less frequent than previously reported. Pre-treatment or monitoring liver biopsies in accordance with the current guidelines have little impact on patient management.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Bradley, R. ; Burt, A. J. ; Read, D. J.

    [s.l.] : Nature Publishing Group
    Published 1981
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Calluna seeds were collected from plants growing on heavy metal-contaminated spoil at Parys Mountain, Anglesey, North Wales, and from natural heathland at Stanton Moor, Derbyshire, England. Seedlings of both races were grown aseptically on water agar and then transferred to sterile soil in Petri ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    BURT, A. W. A. ; THOMAS, D. C.

    [s.l.] : Nature Publishing Group
    Published 1961
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Mineral balance of herbage3, low sodium intakes4, and increased ruminal ammonia production5 from the appreciable amounts of soluble nitrogenous constituents of spring herbage have all been suggested as precipitating factors, but none of these has been consistently implicated in clinical cases of ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    COOPER, P. D. ; BURT, A. M. ; WILSON, J. N.

    [s.l.] : Nature Publishing Group
    Published 1958
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Medium was pumped at a known rate from a reservoir to a culture vessel kept at 37 C. (20.1. Pyrex aspirators), which overflowed at a constant level into a cooled receiver and was harvested once weekly. Culture vessel and receiver were gassed with mixed carbon dioxide, oxygen and nitrogen and ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20