Search Results - (Author, Cooperation:A. Brill)
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1Hayakawa, K., Formica, A. M., Nakao, Y., Ichikawa, D., Shinton, S. A., Brill-Dashoff, J., Smith, M. R., Morse, H. C., Hardy, R. R.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-07-10Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
2N. Korin ; M. Kanapathipillai ; B. D. Matthews ; M. Crescente ; A. Brill ; T. Mammoto ; K. Ghosh ; S. Jurek ; S. A. Bencherif ; D. Bhatta ; A. U. Coskun ; C. L. Feldman ; D. D. Wagner ; D. E. Ingber
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-07-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Biomimetic Materials ; Blood Circulation ; Drug Delivery Systems/*methods ; Fibrinolytic Agents/*administration & dosage ; Hemodynamics ; Hemorheology ; Lactic Acid ; Male ; Mesenteric Arteries ; Mesenteric Vascular Occlusion/*drug therapy ; Mice ; Mice, Inbred C57BL ; Microfluidic Analytical Techniques ; Models, Anatomic ; *Nanoparticles ; Polyglycolic Acid ; Pulmonary Embolism/*drug therapy ; Stress, Mechanical ; Thrombosis/*drug therapy/prevention & control ; Tissue Plasminogen Activator/*administration & dosagePublished by: -
3DeMarco, L. G. ; Brill, A. S. ; Crabb, D. G.
College Park, Md. : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The measurements reported below quantify the stability and decay of hydrogen, deuterium, and nitrogen atoms in frozen ammonia above 100 K. The decay of H atoms is observed on a time scale of minutes in the range of 100–110 K and follows first-order kinetics. Analogous decays of D and N atoms are observed in the ranges 105–120 and 140–160 K, respectively. Activation energies for the decay processes range from 0.1 to 0.4 eV. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Brill, A. ; Baram, D. ; Sela, U. ; Salamon, P. ; Mekori, Y. A. ; Hershkoviz, R.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background Mast cells exert profound pleiotropic effects on immune cell reactions at inflammatory sites, where they are most likely influenced not only by the extracellular matrix (ECM) and inflammatory mediators but also by the proximity of activated T lymphocytes. We recently reported that activated T cells induce mast cell degranulation with the release of TNF-α, and that this activation pathway is mediated by lymphocyte function-associated antigen-1 (LFA-1)/intercellular adhesion molecule-1 (ICAM-1) binding.Objective To determine how this contact between the two cell types can modulate mast cell behaviour in an inflammatory milieu by examining the adhesion of mast cells to endothelial cells and ECM ligands in an integrin-dependent manner.Methods Human mast cells (HMC-1) were co-cultured with resting or activated T cells followed by testing their adhesion to endothelial cell and ECM ligands, stromal derived factor-1α (SDF-1α)-induced migration, and western blotting.Results Co-culturing HMC-1 with activated, but not with resting T cells resulted in marked stimulation of mast cell adhesion to vascular cell adhesion molecule-1 and ICAM-1 in a very late antigen-4- and LFA-1-dependent fashion. In addition, activated T cells or T cell membranes promoted HMC-1 adhesion to fibronectin (FN) and laminin. This effect was accompanied by the phosphorylation of extracellular regulated kinase and p38, but not of c-Jun N-terminal kinase. Importantly, the adhesive property of mast cells depended exclusively on the direct contact between the two cell types, since neither supernatants from activated T cells nor separation of the two cell populations with a porous membrane affected mast cell adhesion to FN. Furthermore, similar results were obtained when mast cells were incubated with purified membranes from activated T cells. These results suggest that, in addition to stimulating mast cell degranulation, the proximity of activated T lymphocytes to mast cells can mediate the adhesion of mast cell precursors to the endothelial ligands and ECM. Activated T cells also stimulated SDF-1α-induced mast cell migration.Conclusion This symbiotic relationship between the two types of immune cells may serve to direct mast cells to specific sites of inflammation where their effector functions are required.Type of Medium: Electronic ResourceURL: -
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ISSN: 0029-2397Topics: English, American StudiesHistoryURL: -
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ISSN: 0883-2889Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringType of Medium: Electronic ResourceURL: -
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ISSN: 0883-2889Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringType of Medium: Electronic ResourceURL: -
8Erickson, J.J. ; Eastwold, E.L. ; Parker, J.F. ; Baglan, R.J. ; Larsen, K.H. ; Bertrand Brill, A.
Amsterdam : ElsevierStaff ViewISSN: 0029-554XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1807Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: