Search Results - (Author, Cooperation:A. Bardelli)

Showing 1 - 10 results of 10, query time: 0.17s Refine Results
  1. 1
    A. Prahallad ; C. Sun ; S. Huang ; F. Di Nicolantonio ; R. Salazar ; D. Zecchin ; R. L. Beijersbergen ; A. Bardelli ; R. Bernards
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-01-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal, Humanized ; Antineoplastic Agents/pharmacology/therapeutic use ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cetuximab ; Colorectal Neoplasms/*drug therapy/*enzymology/genetics/pathology ; Drug Resistance, Neoplasm/*drug effects ; Drug Synergism ; Enzyme Activation/drug effects ; Erlotinib Hydrochloride ; Feedback, Physiological/*drug effects ; Female ; HEK293 Cells ; Humans ; Indoles/pharmacology/therapeutic use ; Melanoma/drug therapy/metabolism ; Mice ; Protein Kinase Inhibitors/pharmacology/therapeutic use ; Proto-Oncogene Proteins B-raf/*antagonists & ; inhibitors/chemistry/*genetics/metabolism ; Quinazolines/pharmacology/therapeutic use ; RNA Interference ; Receptor, Epidermal Growth Factor/*agonists/antagonists & inhibitors/metabolism ; Sulfonamides/pharmacology/therapeutic use ; Xenograft Model Antitumor Assays
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-03-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Antineoplastic Agents/*administration & dosage/*pharmacology ; Cell Aging/drug effects ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm/drug effects/genetics ; Female ; Flow Cytometry ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Library ; Humans ; Indoles/administration & dosage/pharmacology ; Melanoma/*drug therapy/enzymology/genetics/pathology ; Mice ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors/metabolism ; Protein Kinase Inhibitors/*administration & dosage/*pharmacology ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors/*genetics/metabolism ; RNA, Small Interfering ; Receptor Protein-Tyrosine Kinases/biosynthesis/genetics/metabolism ; Receptor, Epidermal Growth Factor/biosynthesis/genetics/metabolism ; Receptor, Platelet-Derived Growth Factor beta/biosynthesis/genetics/metabolism ; SOXE Transcription Factors/deficiency/genetics ; Signal Transduction/drug effects ; Sulfonamides/administration & dosage/pharmacology ; Transforming Growth Factor beta/metabolism/pharmacology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2012-06-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; Antibodies, Monoclonal/*pharmacology/therapeutic use ; Antibodies, Monoclonal, Humanized ; Cell Line, Tumor ; Cetuximab ; Colorectal Neoplasms/*drug therapy/*genetics/pathology ; Disease Progression ; Drug Resistance, Neoplasm/*drug effects/genetics ; Genes, ras/genetics ; Humans ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors ; Mutation/*genetics ; Promoter Regions, Genetic/genetics ; Proto-Oncogene Proteins/*genetics ; Receptor, Epidermal Growth Factor/*antagonists & inhibitors ; ras Proteins/*genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Bardelli, A. ; Ponzetto, C. ; Comoglio, P.M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0168-1656
    Keywords:
    HGF/SF ; MET oncogenic ; Signal transduction ; Tyrosine kinase receptor
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0168-1656(94)90002-7

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1432-1920
    Keywords:
    Key words DIDMOAD syndrome ; Wolfram syndrome ; substantia nigra ; Magnetic resonance imaging
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Wolfram syndrome (DIDMOAD) is a rare diffuse neurodegenerative disorder characterised by diabetes insipidus, diabetes mellitus, optic atrophy, deafness, and a wide variety of abnormalities of the central nervous system, urinary tract and endocrine glands. It may be familial or sporadic. Reported features on MRI of the brain are absence of the physiological high signal of the posterior lobe of the pituitary, shrinkage of optic nerves, chiasm and tracts, atrophy of the hypothalamic region, brain stem, cerebellum, and cerebral cortex. We report a 12-year-old girl with a 5-year history without brain stem, cerebellar or cerebral atrophy. MRI showed an unusual feature: a focus of high signal on PD- and T2-weighted images in the right substantia nigra. This is consistent with previously reported neuropathological post-mortem studies, but has never been reported in vivo.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s002340050832

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    1432-1076
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00441754

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1573-2665
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01811419

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    1573-2665
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01804233

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    1573-2665
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Conclusions Type II tyrosinaemia in Italy has no regional preponderance. Neuromotor retardation and/or microcephaly seem to be correlated with the higher values of tyrosine. Enzyme studies have been refused in all patients. Treatment with a low tyrosine diet has been successful when accepted: since in many patients the diagnosis was made rather late, it is not possible to evaluate the results of the diet for the prevention of neuromotor retardation.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01799723

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1573-2665
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Conclusions Our study reports the first comprehensive evaluation of HOGA in an Italian family, and is thus intended to alert Italian ophthalmologists and paediatricians to this potentially treatable condition in children with even apparently mild visual disturbances. The typical fundoscopic findings make diagnosis possible. Extensive epidemiological investigations could be justified to determine the incidence of this disorder in Italy.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01799726

    Articles: DFG German National Licenses