Dyschromatosis universalis hereditaria
Sethuraman, G. ; D'Souza, M. ; Thappa, D. Mohan ; Srinivas, C. R. ; Smiles, L.
Oxford, UK : Blackwell Science Ltd
Published 2002
Oxford, UK : Blackwell Science Ltd
Published 2002
| ISSN: |
1365-2230
|
|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
|
| Topics: |
Medicine
|
| Notes: |
Summary Dyschromatosis universalis hereditaria is a clinically heterogenous disorder. We report two unrelated Indian patients with dyschromatosis universalis hereditaria, who had generalized and progressive reticulate hyper- and hypo-pigmentation of the skin. The oral mucosa and tongue also showed mottled pigmentation. Intriguingly, the palms and soles were also affected with a diffuse hyper-pigmentation interspersed with spotty de-pigmented macules. Dystrophic nail changes with pterygium formation were seen in one case. Histopathology revealed a variable degree of pigmentary incontinence. Although the precise aetiology of this disorder is not yet known, the clinicopathological findings implicate an inherent abnormality of melanosomes or melanin processing.
|
| Type of Medium: |
Electronic Resource
|
| URL: |