Secretion of γ-Interferon at the Cellular Level
ANDERSSON, U. ; MARTINEZ-MAZA, O. ; ANDERSSON, J. ; BRITTON, S. ; GAOLER, H. ; LEY, M. ; MODROW, S.
Oxford, UK : Blackwell Publishing Ltd
Published 1984
Oxford, UK : Blackwell Publishing Ltd
Published 1984
| ISSN: |
1365-3083
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|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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| Topics: |
Medicine
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| Notes: |
Using a haemolytic plaque assay for y-interferon (IFN-γ) secretion we found that in vitro Epstein-Barr virus (EBV) exposure of peripheral blood mononuclear cells from EBV immune individuals led to IFN-y secretion, which was apparent wiihin 6 h after virus coniact and peaked 12–24 h after induction. Live, ultraviolel-light-irradiaicd and heat-inactivated virions all caused IFN-γ secretion. In contrast, blood mononuclear cells from EBV non-immune adults or neonates could not be activated to IFN-y production by EBV.
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| Type of Medium: |
Electronic Resource
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| URL: |