A Single Radioimmunological Assay for Serotonin, N-Acetylserotonin, 5-Methoxytryptamine, and Melatonin
Geffard, M. R. ; Puizillout, J. J. ; Delaage, M. A.
Oxford, UK : Blackwell Publishing Ltd
Published 1982
Oxford, UK : Blackwell Publishing Ltd
Published 1982
| ISSN: |
1471-4159
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|---|---|
| Source: |
Blackwell Publishing Journal Backfiles 1879-2005
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| Topics: |
Medicine
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| Notes: |
Abstract: A radioimmunoassay of melatonin using a new iodinated derivative has been developed. Simple chemical treatments have then been designed to convert serotonin, N-acetylserotonin, and 5-methoxytryptamine to melatonin. Thus these four molecules, belonging to the same metabolic pathway, were separately assayed in the same radioimmunological system at the same sensitivity level (0.01 pmol). Some biological results on the circadian variations of melatonin and serotonin in blood, pineal, and miscellaneous brain structures are presented.
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| Type of Medium: |
Electronic Resource
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| URL: |