Conversion of Lactococcus lactis from homolactic to homoalanine fermentation through metabolic engineering
Kleerebezem, Michiel ; Schanck, André N. ; Ferain, Thierry ; Hugenholtz, Jeroen ; Delcour, Jean ; de Vos, Willem M. ; Hols, Pascal
[s.l.] : Nature America Inc.
Published 1999
[s.l.] : Nature America Inc.
Published 1999
| ISSN: |
1546-1696
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| Source: |
Nature Archives 1869 - 2009
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| Topics: |
Biology
Process Engineering, Biotechnology, Nutrition Technology
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| Notes: |
[Auszug] We report the engineering of Lactococcus lactis to produce the amino acid l-alanine. The primary end product of sugar metabolism in wild-type L. lactis is lactate (homolactic fermentation). The terminal enzymatic reaction (pyruvate + NADH→l-lactate + NAD+) is performed by l-lactate ...
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| Type of Medium: |
Electronic Resource
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| URL: |