Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system - Liou, H.-C.; Baltimore, D. (Elsevier)
The interplay between proteins of the NF-ηB/rel and IηB families is a tightly regulated process that ensures appropriate responses to specific environmental and developmental signals. Various mechanisms are utilized in regulating NF-ηB/rel and IxB activities, some unique to this transcription factor system. All of these regulatory strategies converge towards one purpose, namely the controlled nuclear translocation of activated NF-ηB/rel protein complexes. The variety of rel-related and ankyrin repeat containing subunits makes regulation of this system both rich and complicated.
http://dx.doi.org/10.1016/0955-0674(93)90014-H
Keywords: W; WW-YZ